A5050879856- Air Quality and Health Impacts
- Noise Effects and Management
- Climate Change and Health Impacts
- Indoor Air Quality and Microbial Exposure
- Asthma and respiratory diseases
- Air Quality Monitoring and Forecasting
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Vehicle emissions and performance
- Pediatric health and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infection Control and Ventilation
- COVID-19 and Mental Health
- Dental Research and COVID-19
- Occupational exposure and asthma
- Healthcare and Environmental Waste Management
- Zoonotic diseases and public health
- Chemokine receptors and signaling
- Atherosclerosis and Cardiovascular Diseases
- Inflammasome and immune disorders
- Macrophage Migration Inhibitory Factor
- Contact Dermatitis and Allergies
- Long-Term Effects of COVID-19
- Odor and Emission Control Technologies
- Environmental Impact and Sustainability
Centre for Palaeogenetics
2024-2025
Karolinska Institutet
2011-2025
Public Health Agency of Sweden
2019-2022
Stockholm County Council
2012-2015
The University of Melbourne
2011
Chronic obstructive pulmonary disease (COPD) will soon be the third most common cause of death globally. Despite smoking cessation, neutrophilic mucosal inflammation persistently damages airways and fails to protect from recurrent infections. This maladaptive excess is also refractory glucocorticosteroids (GC). Here, we identify serum amyloid A (SAA) as a candidate mediator GC in COPD. Extrahepatic SAA was detected locally COPD bronchoalveolar lavage fluid, which correlated with IL-8...
Objective: We set out to profile the immune mechanisms active in treatment-naive oligoarticular JIA (oJIA) improve understanding of its immunopathogenesis, identify potential biomarkers that can aid diagnosis, predictions and correlate with clinical disease parameters. Methods: Using Olink proteomics (Inflammation Panel), we defined compared inflammation profiles 38 plasma 62 synovial fluid (SF) oJIA samples, samples from healthy age- sex-matched controls (HC), 12 SF non-arthritic 26 knee...
Asthma is a disease affecting many locations throughout the airway. Most studies have used spirometry as primary assessment of airway obstruction, method that may be less sensitive in regard to peripheral obstruction. The aim this study was elucidate associations between asthma phenotypes based on age onset and duration symptoms, (i) (ii) small involvement measured by impulse oscillometry (IOS) adolescence.Children adolescents taking part BAMSE, prospective birth cohort study, performed at 8...
The world’s challenges of climate change, damage to ecosystems, and social health inequalities require changes in human behaviours at every level organisation, among governments, business, communities, individuals. An important question is how behaviour change can be enabled supported the scale speed required. research reported this paper describes lessons for good practice changing contexts modify a triple win health, equity environmental sustainability. Authors synthesised learning from...
The traffic microenvironment has been shown to be a major contributor the total personal exposure of black carbon (BC), and is key local actions aiming at reducing health risks associated with such exposure. main aim study was get better understanding determinants traffic-related BC in an urban environment. Personal ambient levels monitored while walking, cycling traveling by bus or car along four streets alternative routes simultaneously. Monitoring performed during morning afternoon peak...
The benefits of improved air quality on asthma remain understudied.
Short-term studies of health effects from ambient air pollution usually rely on fixed site monitoring data or spatio-temporal models for exposure characterization, but the relation to personal is often not known.
Objectives The aim of the study was to determine exposure–response relationships in salmon‐processing workers. Methods Cross‐shift FEV1, acute respiratory symptoms, and exposure total protein, parvalbumin endotoxin were main variables measured during one workweek. Exposure–response analyzed by Generalized Estimation Equations cross‐week data multiple regressions day‐to‐day data. Results Exposure levels higher those workers who reported use water hose. GEE showed negative coefficients for...
<i>Background/Aim:</i> To protect susceptible subjects from exposure to horse allergen, a Swedish national report recommended distance of at least 500 m between homes and stables other areas with horses. The aim this project was study indoor outdoor levels allergen in relation tracks. <i>Methods:</i> Indoor outdoorsamples were collected Petri dishes 49 sites different housing near track for trotting In the apartments, placed on bookshelf living room height...
Background. The presence of horse allergen in public places is not well-known, unlike for instance cat and dog allergens, which have been studied extensively. aim was to investigate the schools what extent influence number children with regular contact on indoor levels. Methods. Petri dishes were used collect airborne dust samples during one week classrooms. In some cases, vacuumed also collected. All extracted, frozen analysed Equ cx content shortly after sampling, re-analysed six years...
Background: Dust from indoor environments consists of animal allergens, pollen, endotoxins, and other substances which may exacerbate symptoms in sensitive individuals. In prospective cohort studies, dust is often collected order to assess allergen exposure possible relationships health outcomes. Typically, large numbers samples are kept frozen until further analysis, sometimes several years later. To date, there insufficient knowledge about what happens the its contents during storage....
Abstract Epidemiologic studies on health effects of air pollution usually rely time-series ambient monitoring data or spatially modelled levels. Little is known how well these estimate residential outdoor and indoor We investigated the agreement measured black carbon (BC) levels outdoors indoors with fixed-site calculated using a Gaussian dispersion model. One-week BC measurements were conducted for 15 families living in central Stockholm. Time-series from urban background street-level...
There is limited knowledge about how asthma affects sickness absence in young adulthood. To examine and different phenotypes affect among adults potential modifying factors. A secondary aim was to estimate productivity losses related for asthma. The study included 2,391 participants from the Swedish population-based cohort BAMSE. Information on asthma, phenotypes, lifestyle factors were collected questionnaires clinical examinations at ∼24 years of age (2016–2019). >14 days obtained a...
Background and Aims: Urban populations are exposed to a complex mixture of air pollution, including volatile organic compounds (VOC), nitrogen oxides polycyclic aromatic hydrocarbons (PAH), which carcinogenic or may be seen as indicators co-emitted carcinogens. The aim the present study was measure personal exposure pollutants in Stockholm, Sweden, time-trends, compare levels with concentrations at outdoor reference sites. Methods: Forty participants, 20-50 years age, randomly selected among...