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Carolina P. Hernández-Fuentes

ORCID: 0000-0002-4522-4740
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About
Contact & Profiles
A5061013114
Research Areas
  • Renin-Angiotensin System Studies
  • Receptor Mechanisms and Signaling
  • Mitochondrial Function and Pathology
  • Hormonal Regulation and Hypertension
  • ATP Synthase and ATPases Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Cardiovascular Function and Risk Factors
  • Pulmonary Hypertension Research and Treatments
  • Metabolism, Diabetes, and Cancer
  • Signaling Pathways in Disease
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Parkinson's Disease Mechanisms and Treatments

Advanced Center for Chronic Diseases
 2017-2022

University of Chile
 2017-2022

 Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells
OPENALEX - Publications 
Valentina Parra Roberto Bravo Ignacio Norambuena‐Soto Carolina P. Hernández-Fuentes Andrés G. Gómez-Contreras and 5 more Hugo Verdejo Rosemarie Mellado Mario Chiong Sergio Lavandero Pablo Castro

10.1016/j.bbadis.2017.07.018 article EN publisher-specific-oa Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2017-07-22
 Down Syndrome Critical Region 1 Gene, Rcan1 , Helps Maintain a More Fused Mitochondrial Network
OPENALEX - Publications 
Valentina Parra Francisco Altamirano Carolina P. Hernández-Fuentes Dan Tong V.O. Kyrychenko and 7 more David Rotter Zully Pedrozo Joseph A. Hill Verónica Eisner Sergio Lavandero Jay W. Schneider Beverly A. Rothermel

The regulator of calcineurin 1 (RCAN1) inhibits CN (calcineurin), a Ca2+-activated protein phosphatase important in cardiac remodeling. In humans, RCAN1 is located on chromosome 21 proximity to the Down syndrome critical region. hearts and brains Rcan1 KO mice are more susceptible damage from ischemia/reperfusion (I/R); however, underlying cause not known.Mitochondria key mediators I/R damage. goal these studies was determine impact mitochondrial dynamics function.Using both neonatal...

10.1161/circresaha.117.311522 article EN Circulation Research 2018-01-23
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