Fadime Kıran

ORCID: 0000-0002-4536-2959
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Oral microbiology and periodontitis research
  • Microbial Metabolites in Food Biotechnology
  • Genomics and Phylogenetic Studies
  • Gut microbiota and health
  • Protein Hydrolysis and Bioactive Peptides
  • Antimicrobial Peptides and Activities
  • Essential Oils and Antimicrobial Activity
  • Bee Products Chemical Analysis
  • Bacterial biofilms and quorum sensing
  • Silk-based biomaterials and applications
  • Food Quality and Safety Studies
  • Fermentation and Sensory Analysis
  • Tissue Engineering and Regenerative Medicine
  • Insect and Pesticide Research
  • Bone Tissue Engineering Materials
  • Insect and Arachnid Ecology and Behavior
  • Mycotoxins in Agriculture and Food
  • Listeria monocytogenes in Food Safety
  • Salivary Gland Disorders and Functions
  • Genetically Modified Organisms Research
  • Proteoglycans and glycosaminoglycans research
  • Collagen: Extraction and Characterization
  • Biochemical and Structural Characterization
  • Dental Health and Care Utilization

Ankara University
2014-2025

This study aimed to develop and evaluate a CpG oligodeoxynucleotide (CpG ODN)-adjuvanted trivalent inactivated Salmonella vaccine including S. enterica subsp. Enterica serovar Typhimurium, Enteritidis, serotype Infantis, for its immunogenic efficacy in chickens. The immunomodulatory effects of various ODNs were assessed based on proinflammatory cytokine secretion the expression levels CD80, CD86, MHC-II chicken cell lines HD11 DT40. According results, D35 3CG PO, MB, 1466 Acore K3 which...

10.1016/j.psj.2025.105024 article EN cc-by-nc-nd Poultry Science 2025-03-01

Mastitis is one of the most important and multi-factorial diseases affecting dairy cows. This study was conducted to evaluate effect postbiotics secreted by lactic acid bacteria on mastitis. Within this aim, a total 10 raw milk samples healthy cows were processed for isolation microbiota-derived bacteria. Following protocol, 24 isolates showing phenotypic characters similar Lactobacillus species specific MRS agar selected screened their antibacterial activity against mastitis-causing...

10.1080/1828051x.2021.1958077 article EN cc-by Italian Journal of Animal Science 2021-01-01

Introduction: This present study aimed to isolate beneficial bacteria from honey bee pollen microbiota and investigate the metabolite profiles of postbiotics exhibiting anti-microbial anti-oxidant properties. Methodology: Pour plate technique was used (Apis mellifera L.) samples. Different colonies grown on agar plates were selected screened for their activity against important pathogens using well diffusion assay. The isolates that exhibited remarkable inhibitory effects all tested...

10.3855/jidc.16921 article EN cc-by The Journal of Infection in Developing Countries 2023-04-30

Tissue engineering and regenerative medicine have evolved into a different concept, the so-called clinical tissue engineering. Within this context, synthesis of next-generation inorganic-organic hybrid constructs without use chemical crosslinkers emerges with great potential for treating bone defects. Here, we propose sophisticated approach synthesizing cost-effective boron (B)- silicon (Si)-incorporated collagen/hair keratin (B-Si-Col-HK) cryogels help sol-gel reactions. In approach,...

10.1021/acsabm.1c00805 article EN ACS Applied Bio Materials 2021-09-06

Previous studies have indicated that the exopolysaccharides of lactic acid bacteria exhibit antibiofilm activity against non-oral by preventing their initial adhesion to surfaces and downregulating expression genes responsible for biofilm formation. The aims this study were (1) characterize (EPSs)

10.3390/microorganisms10112200 article EN cc-by Microorganisms 2022-11-07

Abstract Extracellular nanovesicles, particularly exosomes, can deliver their diverse bioactive biomolecular content, including miRNAs, proteins, and lipids, thus providing a context for investigating the capability of exosomes to induce stem cells toward lineage‐specific tissue regeneration. In this study, it is demonstrated that rat subventricular zone neural cell‐derived (rSVZ‐NSCExo) control neural‐lineage specification human mesenchymal (hMSCs). Microarray analysis shows miRNA content...

10.1002/adbi.202101317 article EN Advanced Biology 2022-03-28

To satisfy the increasing demand for protein supply of growing global population, cultivated meat is being garnered significant attention that can meet consumer needs with a reduced impact on planet nowadays. Due to nascent industry, there are still many hurdles overcome such as cost reduction. This study aims investigate effect microbiota-derived postbiotics reduce need growth factors (GFs) or fetal bovine serum (FBS), main drivers this technology. For purpose, postbiotic Biftek-1 (B-1) was...

10.3390/su152316164 article EN Sustainability 2023-11-21

Postbiotics offer better properties than probiotics. This study investigated the antimicrobial activity of Lactiplantibacillus plantarum EIR/IF-1 postbiotics against pH-adaptive bacteria, namely Prevotella denticola, Fusobacterium nucleatum, and Streptococcus sanguinis. Cell-free culture media L. were used as in either crude (acidic) or neutralized form to also understand non-pH-dependent potential. Minimum inhibitory concentration (MIC), minimum bactericidal (MBC), viable cell counts...

10.3390/microbiolres14030098 article EN cc-by Microbiology Research 2023-09-18

Abstract Mesenterocin, a small anti‐ listerial peptide of 3.5 kDa produced by Leuconostoc mesenteroides subsp. OZ at the end exponential growth was inactivated proteolytic enymes, stable to cold storage (4 °C for 3 d), heat, organic solvents and surfactants, exhibited maximum bactericidal mode activity in pH range 10. Although Leu. harboured plasmids ranging size from 3.6 9.7 kbp, no evidence obtained indicating that mesenterocin under control extrachromosomal because loss bacteriocin...

10.1002/jobm.201000240 article EN Journal of Basic Microbiology 2011-02-07

Abstract To improve the hydrophobic character of silk and impart iodine complex ion adsorption, surface woven fabric is enriched by different functional groups through grafting N ‐vinylpyrrolidone (NVP), ethylene glycol dimethacrylate (EGDMA), their mixtures (NVP–EGDMA). The dominant fibrous texture enables an efficient graft copolymerization in terms high yield (>30%) after applying a mild degumming process. structural morphological alterations are evidenced with attenuated total...

10.1002/macp.202400039 article EN Macromolecular Chemistry and Physics 2024-04-13

Her yıl milyonlarca insanın ölümüne sebep olan kanser, kardiyovasküler hastalıklardan sonra en tehlikeli hastalık grubu olarak kabul edilmektedir. Kanser tedavisi amacıyla radyoterapi, kemoterapi ve immünoterapi gibi yöntemler yaygın uygulanmaktadır. Ancak, mevcut tedavi yöntemlerinin hastada olumsuz yan etkilere neden olması ek yaklaşımlarına duyulan ihtiyacı artırmaktadır. Mikrobiyotanın insan sağlığı üzerine etkilerine yönelik çalışmalar son yıllarda hız kazanmıştır. Kanser-mikrobiyota...

10.18614/deutip.1400790 article TR Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi 2024-06-13

Honey is known to be a natural food product with antibacterial and wound-healing properties. Among its different types, some attributed more medical applications including Manuka honey. In this study, wound healing-related parameters were systematically investigated on two types of Turkish honey (Chestnut Anzer), in comparison Chestnut had considerable amount hydrogen peroxide (5 μg/mL) whereas Anzer did not contain any. Additionally, the highest acidity among all tested samples (24.50...

10.24925/turjaf.v12i10.1826-1834.6869 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2024-10-15
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