- Probiotics and Fermented Foods
- Oral microbiology and periodontitis research
- Microbial Metabolites in Food Biotechnology
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Bacterial biofilms and quorum sensing
- Silk-based biomaterials and applications
- Food Quality and Safety Studies
- Fermentation and Sensory Analysis
- Tissue Engineering and Regenerative Medicine
- Insect and Pesticide Research
- Bone Tissue Engineering Materials
- Insect and Arachnid Ecology and Behavior
- Mycotoxins in Agriculture and Food
- Listeria monocytogenes in Food Safety
- Salivary Gland Disorders and Functions
- Genetically Modified Organisms Research
- Proteoglycans and glycosaminoglycans research
- Collagen: Extraction and Characterization
- Biochemical and Structural Characterization
- Dental Health and Care Utilization
Ankara University
2014-2025
This study aimed to develop and evaluate a CpG oligodeoxynucleotide (CpG ODN)-adjuvanted trivalent inactivated Salmonella vaccine including S. enterica subsp. Enterica serovar Typhimurium, Enteritidis, serotype Infantis, for its immunogenic efficacy in chickens. The immunomodulatory effects of various ODNs were assessed based on proinflammatory cytokine secretion the expression levels CD80, CD86, MHC-II chicken cell lines HD11 DT40. According results, D35 3CG PO, MB, 1466 Acore K3 which...
Mastitis is one of the most important and multi-factorial diseases affecting dairy cows. This study was conducted to evaluate effect postbiotics secreted by lactic acid bacteria on mastitis. Within this aim, a total 10 raw milk samples healthy cows were processed for isolation microbiota-derived bacteria. Following protocol, 24 isolates showing phenotypic characters similar Lactobacillus species specific MRS agar selected screened their antibacterial activity against mastitis-causing...
Introduction: This present study aimed to isolate beneficial bacteria from honey bee pollen microbiota and investigate the metabolite profiles of postbiotics exhibiting anti-microbial anti-oxidant properties. Methodology: Pour plate technique was used (Apis mellifera L.) samples. Different colonies grown on agar plates were selected screened for their activity against important pathogens using well diffusion assay. The isolates that exhibited remarkable inhibitory effects all tested...
Tissue engineering and regenerative medicine have evolved into a different concept, the so-called clinical tissue engineering. Within this context, synthesis of next-generation inorganic-organic hybrid constructs without use chemical crosslinkers emerges with great potential for treating bone defects. Here, we propose sophisticated approach synthesizing cost-effective boron (B)- silicon (Si)-incorporated collagen/hair keratin (B-Si-Col-HK) cryogels help sol-gel reactions. In approach,...
Previous studies have indicated that the exopolysaccharides of lactic acid bacteria exhibit antibiofilm activity against non-oral by preventing their initial adhesion to surfaces and downregulating expression genes responsible for biofilm formation. The aims this study were (1) characterize (EPSs)
Abstract Extracellular nanovesicles, particularly exosomes, can deliver their diverse bioactive biomolecular content, including miRNAs, proteins, and lipids, thus providing a context for investigating the capability of exosomes to induce stem cells toward lineage‐specific tissue regeneration. In this study, it is demonstrated that rat subventricular zone neural cell‐derived (rSVZ‐NSCExo) control neural‐lineage specification human mesenchymal (hMSCs). Microarray analysis shows miRNA content...
To satisfy the increasing demand for protein supply of growing global population, cultivated meat is being garnered significant attention that can meet consumer needs with a reduced impact on planet nowadays. Due to nascent industry, there are still many hurdles overcome such as cost reduction. This study aims investigate effect microbiota-derived postbiotics reduce need growth factors (GFs) or fetal bovine serum (FBS), main drivers this technology. For purpose, postbiotic Biftek-1 (B-1) was...
Postbiotics offer better properties than probiotics. This study investigated the antimicrobial activity of Lactiplantibacillus plantarum EIR/IF-1 postbiotics against pH-adaptive bacteria, namely Prevotella denticola, Fusobacterium nucleatum, and Streptococcus sanguinis. Cell-free culture media L. were used as in either crude (acidic) or neutralized form to also understand non-pH-dependent potential. Minimum inhibitory concentration (MIC), minimum bactericidal (MBC), viable cell counts...
Abstract Mesenterocin, a small anti‐ listerial peptide of 3.5 kDa produced by Leuconostoc mesenteroides subsp. OZ at the end exponential growth was inactivated proteolytic enymes, stable to cold storage (4 °C for 3 d), heat, organic solvents and surfactants, exhibited maximum bactericidal mode activity in pH range 10. Although Leu. harboured plasmids ranging size from 3.6 9.7 kbp, no evidence obtained indicating that mesenterocin under control extrachromosomal because loss bacteriocin...
Abstract To improve the hydrophobic character of silk and impart iodine complex ion adsorption, surface woven fabric is enriched by different functional groups through grafting N ‐vinylpyrrolidone (NVP), ethylene glycol dimethacrylate (EGDMA), their mixtures (NVP–EGDMA). The dominant fibrous texture enables an efficient graft copolymerization in terms high yield (>30%) after applying a mild degumming process. structural morphological alterations are evidenced with attenuated total...
Her yıl milyonlarca insanın ölümüne sebep olan kanser, kardiyovasküler hastalıklardan sonra en tehlikeli hastalık grubu olarak kabul edilmektedir. Kanser tedavisi amacıyla radyoterapi, kemoterapi ve immünoterapi gibi yöntemler yaygın uygulanmaktadır. Ancak, mevcut tedavi yöntemlerinin hastada olumsuz yan etkilere neden olması ek yaklaşımlarına duyulan ihtiyacı artırmaktadır. Mikrobiyotanın insan sağlığı üzerine etkilerine yönelik çalışmalar son yıllarda hız kazanmıştır. Kanser-mikrobiyota...
Honey is known to be a natural food product with antibacterial and wound-healing properties. Among its different types, some attributed more medical applications including Manuka honey. In this study, wound healing-related parameters were systematically investigated on two types of Turkish honey (Chestnut Anzer), in comparison Chestnut had considerable amount hydrogen peroxide (5 μg/mL) whereas Anzer did not contain any. Additionally, the highest acidity among all tested samples (24.50...