A5047662427- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Supercapacitor Materials and Fabrication
- Porphyrin and Phthalocyanine Chemistry
- Advanced battery technologies research
- Advanced Battery Materials and Technologies
- Electrocatalysts for Energy Conversion
- Melanoma and MAPK Pathways
- Catalytic Processes in Materials Science
- Synthesis and biological activity
- Quinazolinone synthesis and applications
- Crystallography and molecular interactions
- Metal-Catalyzed Oxygenation Mechanisms
- Lignin and Wood Chemistry
- Photosynthetic Processes and Mechanisms
- Advanced Battery Technologies Research
- Tryptophan and brain disorders
- Ionic liquids properties and applications
- Photochemistry and Electron Transfer Studies
- Nanomaterials for catalytic reactions
- Flame retardant materials and properties
- HIV/AIDS drug development and treatment
- Luminescence and Fluorescent Materials
- Hepatitis C virus research
- Catalysis for Biomass Conversion
University of Science and Technology of China
2020-2024
Chinese Academy of Sciences
2023-2024
State Key Laboratory of Biotherapy
2023
Sichuan University
2023
Hefei National Center for Physical Sciences at Nanoscale
2020-2022
Merck & Co., Inc., Rahway, NJ, USA (United States)
2011-2021
Microscale (United States)
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2020
Southwest Jiaotong University
2018
Changsha University of Science and Technology
2018
Zn–Mn batteries with two-electron conversion reactions simultaneously on the cathode and anode harvest a high voltage plateau energy density. However, zinc faces dendrite growth parasitic side while Mn2+/MnO2 reaction involves oxygen evolution possesses poor reversibility. Herein, novel nanomicellar electrolyte using methylurea (Mu) has been developed that can encapsulate ions in nanodomain structure to guide homogeneous deposition of Zn2+/Mn2+ form controlled release under an external...
Rapid initiation of apoptosis can be induced by photodynamic therapy, depending on the cell line and sensitizer employed. In this study, we evaluated responses to two structurally related photosensitizing agents, using P388 murine leukemia in culture. Photodamage mediated tin etiopurpurin involved lysosomes mitochondria yielded a rapid apoptotic response; nuclei were observed within 60 min after PDT. A drug analog, octaethylpurpurin amidine, targeted lysosomes, membranes; not until 24 h...
Constitutive activation of ERK1/2 occurs in various cancers, and its reactivation is a well-described resistance mechanism to MAPK inhibitors. ERK inhibitors may overcome the limitations inhibitor blockade. The dual SCH772984 has shown promising preclinical activity across BRAFV600/RAS-mutant cancer cell lines human xenografts.We have developed an orally bioavailable inhibitor, MK-8353; conducted studies demonstrate activity, pharmacodynamic endpoints, dosing, schedule; completed study...
Low-cost and quasi-solid-state polyelectrolyte hydrogel accommodating a superhigh concentration of CH<sub>3</sub>COOK has been prepared for supercapacitors with high ionic conductivity electrochemical window.
The green synthesis of ionic gels using alternative feedstock enables the preparation sustainable materials and devices.
Pt@TiO 2 /graphene nanocomposite catalysts have been synthesized with boosted catalytic performance for methanol oxidation.
Chitin is a natural biomass material with wide sources and high application potential, but the solvents for dissolving chitin are very limited. In this work, ternary alkaline deep eutectic (DESs) containing amino acids, urea, 1,8-diazabicyclo [5.4.0] undec-7-ene (DBU) were prepared, which can successfully achieve dissolution of be recycled. By adjusting type acids amount DBU, maximum solubility reach 6.0 wt %. addition, unlike reported acidic DES system, new not only efficiently extracted...
Dicobalt(II) cofacial bisporphyrins anchored by dibenzofuran (DPD) and xanthene (DPX) are efficient electrocatalysts for the four-electron reduction of oxygen to water despite their ca. 4 Å difference in metal–metal distances, suggesting that considerable longitudinal 'Pac-Man' flexibility pillared platforms is origin similar catalytic reactivity these structurally disparate systems.
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTDirect Observation of the "Pac-Man" Effect from Dibenzofuran-Bridged Cofacial BisporphyrinsYongqi Deng, Christopher J. Chang, and Daniel G. NoceraView Author Information Department Chemistry, 6-335 Massachusetts Institute Technology 77 Avenue Cambridge, 02139-4307 Cite this: Am. Chem. Soc. 2000, 122, 2, 410–411Publication Date (Web):December 31, 1999Publication History Received16 August 1999Published online31 December inissue 1 January...
Abstract Aqueous zinc ion hybrid supercapacitors (ZHSCs) have attracted considerable attention owing to the bivalent nature, high abundance, and stability in water‐based system of zinc. High energy density superb power output can be achieved simultaneously by integrating a battery‐type electrode capacitive‐type electrode. However, there are still many issues that remain, including but not only hydrogen evolution reaction, dendrite growth, dramatic capacity loss at low temperatures. Herein,...
The aqueous zinc-ion hybrid supercapacitor (ZHSC) is a prospective energy storage device for next-generation wearable electronics due to its high safety, low cost, and density. However, the preparation of gel electrolytes reported in literature complex time-consuming, which limits their application practice. Herein, we developed robust stretchable eutectogel electrolyte through one-step gelation process situ without introducing additional initiators cross-linkers. consists ternary deep...
A novel polyzwitterionic eutectogel made with a DES (ChCl–EG–urea), zwitterionic sulfobetaine, and Zn(ClO 4 ) 2 high ion conductivity has been used as an electrolyte for quasi-solid state zinc batteries efficient suppression of dendrite growth.
A novel low-cost eutectic electrolyte of Zn(CH 3 COO) 2 /CH COOLi/urea has been prepared for high-voltage and super-stable zinc hybrid batteries with non-flammability sustainability.
A high-strength lignin-based composite adhesive has been prepared by the reaction of lignin and furfural in a green DES, excellent flame retardance, thermal insulating, photothermal properties.
A generally applicable Suzuki methodology for the synthesis of β-derivatized porphyrins has been developed starting from bromoporphyrin 1, which is converted into an air- and water-stable boronate derivative. Metal-mediated cross-coupling latter compound with various aryl bromides furnishes β-arylporphyrins 2 yields similar to those reported derivatization at meso-position. The utility method was demonstrated preparation structural characterization bis-porphyrin 3, directly linked β-positions rings.
An unusually slow electron transfer takes place in the porphyrinato complex 1 (M = Ni, Zn). The rate of this proton-coupled is influenced by a salt bridge which benzoate ions are bound to amidinium group, even solvents with high dielectric constant, such as DMSO.
Abstract Biodegradable hydrogel electrolytes are particularly attractive in the fabrication of all‐solid‐state supercapacitors due to environmental benignity and avoiding leakage. The introduction “water‐in‐salt” (WIS) into hydrogels will further broaden electrochemical stability window aqueous significantly. Meanwhile, addition an organic co‐solvent can effectively overcome inevitable salt precipitation extend temperature adaptability. Herein, situ cross‐linking approach was demonstrated...
Checkpoint inhibitors have demonstrated unprecedented efficacy and are evolving to become standard of care for certain types cancers. However, low overall response rates often hamper the broad utility potential these breakthrough therapies. Combination therapy strategies currently under intensive investigation in clinic, including combination PD-1/PD-L1 agents with IDO1 inhibitors. Here, we report discovery a class heme-binding featuring unique amino-cyclobutarene motif, which was discovered...