- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Dental Research and COVID-19
- Orthodontics and Dentofacial Orthopedics
- Dental materials and restorations
- Temporomandibular Joint Disorders
- Oral and Maxillofacial Pathology
- Dental Anxiety and Anesthesia Techniques
- Dental Education, Practice, Research
- Bone and Dental Protein Studies
- Salivary Gland Disorders and Functions
- Oral and gingival health research
- HIV/AIDS oral health manifestations
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Dental Radiography and Imaging
- Laser Applications in Dentistry and Medicine
- Medical and Biological Sciences
- Dental Erosion and Treatment
- Infective Endocarditis Diagnosis and Management
- Endodontics and Root Canal Treatments
- Alkaline Phosphatase Research Studies
- Oral and Craniofacial Lesions
- dental development and anomalies
- Immunodeficiency and Autoimmune Disorders
University of Pisa
2016-2025
Azienda Ospedaliera Universitaria Pisana
2020-2024
Ospedale Santa Chiara
2018
STMicroelectronics (Czechia)
1999
Little is known about the effect of removable orthodontic appliances on oral colonisation by mutans streptococci (MS). In present study, frequency isolation and serotype distribution MS were evaluated in two groups children, one undergoing therapy with other not subjected to any kind treatment, respectively. Streptococci isolated from dental plaque samples both children identified as basis their morphological biochemical properties then serotyped an enzyme immuno-assay using monoclonal...
The aim of this study was to assess the level salivary immunoglobulins and periodontal status in smokers non-smokers.Unstimulated saliva 30 subjects (mean age 24.2 ± 3.5 years) who were (test group) 25.3 3.8 non-smokers (control collected centrifugated; IgA, IgG, IgM measured with colorimetric immunoenzymatic method. Moreover, following clinical parameters recorded for each subject: plaque index (PI), gingival (GI), probing depth (PD), attachment (CAL).A significantly (p< 0.05) lower Ig...
Aim . The purpose of the present study was to evaluate clinical defects and etiological factors potentially involved in onset MIH a pediatric sample. Methods 120 children, selected from university dental clinic, were included: 60 children (25 boys 35 girls; average age: 9.8 ± 1.8 years) with formed test group (27 33 10.1 2 without constituted control group. Distribution severity evaluated, questionnaire used investigate variables; chi-square, univariate, multivariate statistical tests...
The purpose of this study was to evaluate the sensitivity teeth with MIH in children before and after use a tooth mousse containing casein phosphopeptide amorphous calcium phosphate (CPP-ACP).Forty patients, both males females, aged from 8 13 years old that had molar hypersensitivity were included study. In test group (20 subjects), CPP-ACP used while fluoride toothpaste control group. Dental mechanical thermal stimuli evaluated (T0) 120 days beginning treatment (T1).In group, decreased...
Background/Objectives: The present study evaluated the effectiveness of a prevention protocol involving oral hygiene, instructions, and motivation in patients eligible for hematopoietic stem cell transplantation (HSCT). Methods: Consecutive scheduled HSCT were enrolled. All received complete dental examination aimed at assessing periodontal health status through charting registration levels plaque inflammation. Subsequently, professional hygiene care instructed on motivated toward...
The in vitro activities of human beta-defensin 3 (hBD-3) alone or combined with lysozyme, metronidazole, amoxicillin, and chlorhexidine were investigated the oral bacteria Streptococcus mutans, sanguinis, sobrinus, Lactobacillus acidophilus, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis. hBD-3 showed bactericidal activity against all bacterial species tested. effect was enhanced when peptide used combination antimicrobial agents mentioned above.
The human beta defensin 3 (hBD3) is widely expressed in the oral cavity and exerts strong antibacterial immunomodulatory activities. Hence, we hypothesized that hBD3 could play a protective role maintenance of periodontal homeostasis, it be found gingival crevicular fluid (GCF) healthy individuals those with periodontitis at levels correlating degree health. By using an ELISA assay to quantify GCF, demonstrated peptide present easily detectable majority individuals, but drastically reduced...
Abstract This study investigated the microbial level of Streptococcus mutans and Lactobacillus spp. during an orthodontic treatment, compare data with untreated control subjects. Sixty young adult subjects were selected (average 20.5, DS 1.62), among which 40 underwent treatment (20 treated self-ligating brackets 20 conventional brackets) controls. Plaque Index, salivary flow buffering capacity saliva assessed before beginning treatment. Then counts obtained by using in-office bacteria test....
Nano-hydroxyapatite (nano-HAp) is a biomaterial which finding increasing application in dentistry due to its osteogenic properties and biocompatibility. The aim of the present study review clinical applications nano-HAp dentistry. A literature search was performed PubMeD Scopus. In total, 154 articles were retrieved. Following title abstract analysis, 122 excluded. Further 6 excluded through full-text analysis. systematic conducted on 26 articles. 3 studies, employed for tissue...
The recognition that periodontal diseases are associated with specific pathogens has led to interest in the use of antibacterial drugs for inhibition these microorganisms. On bases, present study was aimed at evaluating tissue distribution new macrolide antibiotic azithromycin patients subjected oral surgery chronic inflammatory both marginal and periapical periodontium.Thirty-two were treated 500 mg/day orally 3 consecutive days, drug concentrations plasma, saliva, normal gingiva,...
People with Down syndrome, a frequent genetic disorder in humans, have increased risk of health problems associated this condition. One clinical feature syndrome is the prevalence and severity periodontal disease comparison general population. Because saliva plays an important role maintaining oral health, present study salivary proteome subjects was investigated to explore modifications respect healthy subjects. Whole 36 subjects, divided age groups 10-17 yr 18-50 yr, analyzed by top-down...
Aim. To investigate and compare the efficiency of two appliances for molar distalization: bone-anchored distal screw (DS) traditional tooth-supported jet (DJ) distalization anchorage loss. Methods. Tests (18 subjects) were treated with a DS controls DJ. Lateral cephalograms obtained before at end analysed. Shapiro Wilk test, unpaired t-test, Wilcoxon rank-sum test applied according to values distribution. The α level was fixed 0.05. Results. Maxillary first molars successfully distalized...
Pulpotomy is the surgical removal of entire coronal pulp with preservation radicular vitality. The purpose this retrospective study was to evaluate clinical and radiographic success pulpotomy primary molars using two materials, biodentine calcium hydroxide. Records 400 in 360 paediatric participants (mean age: 7.5 ± 1.6 years, ranging from 5 9 years) dental caries who required therapy were included study. Biodentine used on 200 teeth, hydroxide (CH) another as a material. Clinical evaluation...
During the months of March and April 2020, Italy saw an exponential outbreak COVID-19 epidemic. Dental practitioners were particularly limited in their routine activity, sole performance urgent treatments was strongly encouraged during peak A survey among dental professionals performed between 6th 13th April, order to evaluate status practice Italy.An online anonymous questionnaire administered retrieve data on procedures performed, preventive measures adopted, predictions future changes...
The tissue penetration of azithromycin, the prototype a new class macrolide antibiotics named azalides, was studied in patients undergoing surgery for third-molar removal. Drug concentrations plasma, saliva, and periodontal tissues were evaluated 28 treated with azithromycin 500 mg/day per os 3 consecutive days. Samples blood, gingiva, alveolar bone collected during oral surgery, 12 hours, 2.5, 4.5, 6.5 days after last dosing, concentration measured microbiologically by using Micrococcus...