José R. Vargas-Rodríguez

ORCID: 0000-0002-4585-2982
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Mitochondrial Function and Pathology
  • Diabetes and associated disorders
  • Inflammasome and immune disorders
  • Infectious Encephalopathies and Encephalitis
  • Nutrition and Health in Aging
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients

Universidad Autónoma de Zacatecas "Francisco García Salinas"
2020-2022

Introduction During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the virus hijacks mitochondria causing damage of its membrane and release mt-DNA into circulation which can trigger innate immunity generate an inflammatory state. In this study, we explored importance peripheral blood as early predictor evolution in patients with COVID-19 to evaluate association between concentration severity disease patient’s outcome. Methods A total 102 (51 cases 51 controls) were...

10.3389/fcimb.2021.754708 article EN cc-by Frontiers in Cellular and Infection Microbiology 2021-12-16

To determine the percentage of positivity close contacts coronavirus disease 19 (COVID-19) patients to depict importance asymptomatic infections in patient-to-patient transmission COVID-19.One hundred subjects were included. Nineteen index COVID-19 cases and 81 traced screened for 2 severe acute respiratory syndrome (SARS-CoV-2) using real-time reverse transcription-polymerase chain reaction. Immunoglobulin M G against SARS-CoV-2 evaluated by rapid test.Thirty-four (42%) study positive...

10.1016/j.ajic.2020.10.002 article EN cc-by-nc-nd American Journal of Infection Control 2020-10-07

Chronic hyperglycemia increases the risk of developing severe COVID-19 symptoms, but related mechanisms are unclear. A mean glucose level upon hospital admission >166 mg/dl correlates positively with acute respiratory distress syndrome in patients hyperglycemia. The objective this study was to evaluate relationship between sustained and outcome hospitalized COVID-19. We also evaluated effect high concentrations on expression angiotensin-converting enzyme 2 (ACE2). carried out a case-control...

10.3390/jpm12050805 article EN Journal of Personalized Medicine 2022-05-17

Since the appearance of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 China, diabetes mellitus (DM) and hyperglycemia patients infected with SARS-CoV, represent independent predictors mortality. Therefore, metabolic control has played a major role prognosis these patients. In current pandemic disease 19 (COVID-19), multiple studies have shown that DM is one main comorbidities associated COVID-19 higher risk complications death. The incidence prevalence death related or...

10.3389/fmed.2021.758414 article EN cc-by Frontiers in Medicine 2022-01-13
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