- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- SARS-CoV-2 and COVID-19 Research
- Mitochondrial Function and Pathology
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Infectious Encephalopathies and Encephalitis
Universidad Autónoma de Zacatecas "Francisco García Salinas"
2020-2022
Introduction During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the virus hijacks mitochondria causing damage of its membrane and release mt-DNA into circulation which can trigger innate immunity generate an inflammatory state. In this study, we explored importance peripheral blood as early predictor evolution in patients with COVID-19 to evaluate association between concentration severity disease patient’s outcome. Methods A total 102 (51 cases 51 controls) were...
To determine the percentage of positivity close contacts coronavirus disease 19 (COVID-19) patients to depict importance asymptomatic infections in patient-to-patient transmission COVID-19.One hundred subjects were included. Nineteen index COVID-19 cases and 81 traced screened for 2 severe acute respiratory syndrome (SARS-CoV-2) using real-time reverse transcription-polymerase chain reaction. Immunoglobulin M G against SARS-CoV-2 evaluated by rapid test.Thirty-four (42%) study positive...
Chronic hyperglycemia increases the risk of developing severe COVID-19 symptoms, but related mechanisms are unclear. A mean glucose level upon hospital admission >166 mg/dl correlates positively with acute respiratory distress syndrome in patients hyperglycemia. The objective this study was to evaluate relationship between sustained and outcome hospitalized COVID-19. We also evaluated effect high concentrations on expression angiotensin-converting enzyme 2 (ACE2). carried out a case-control...
Since the appearance of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 China, diabetes mellitus (DM) and hyperglycemia patients infected with SARS-CoV, represent independent predictors mortality. Therefore, metabolic control has played a major role prognosis these patients. In current pandemic disease 19 (COVID-19), multiple studies have shown that DM is one main comorbidities associated COVID-19 higher risk complications death. The incidence prevalence death related or...