Julia Gorgun

ORCID: 0000-0002-4595-9659
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About
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Celiac Disease Research and Management
  • Microtubule and mitosis dynamics
  • Gastric Cancer Management and Outcomes
  • DNA Repair Mechanisms
  • Gastroesophageal reflux and treatments
  • Digestive system and related health
  • MRI in cancer diagnosis
  • Lung Cancer Treatments and Mutations
  • Eosinophilic Esophagitis
  • 14-3-3 protein interactions
  • Inflammatory Bowel Disease
  • Neurological Disease Mechanisms and Treatments
  • Colorectal Cancer Treatments and Studies
  • HER2/EGFR in Cancer Research
  • Intestinal and Peritoneal Adhesions
  • Pharmacological Effects of Natural Compounds
  • Microscopic Colitis
  • Barrier Structure and Function Studies
  • Protein Tyrosine Phosphatases
  • Ubiquitin and proteasome pathways

Belarusian Medical Academy of Post-Graduate Education
2009-2019

Tubulin is a heterodimer of α and β subunits, both existing as isotypes differing in amino acid sequence encoded by different genes. Specific tubulin have associations with cancer that are not well understood. Previous studies found βII-tubulin expressed number transformed cells this isotype cell nuclei non-microtubule form. The association βII expression its nuclear localization progression has previously been addressed. We here used monoclonal antibody to examine patients colorectal whose...

10.3390/cells8010025 article EN cc-by Cells 2019-01-07

Claudin-2 is a trans-membrane protein-component of tight junctions in epithelial cells. Elevated claudin-2 expression has been reported colorectal cancer (CRC). The aim this study was to investigate the patterns human CRC samples and analyze its association with clinical characteristics treatment outcome. TMAs primary tumors from two cohorts metastatic (mCRC) were used. IHC staining evaluated semi-quantitative manner different regions cell types. also analyzed by immunofluorescence cultures...

10.1007/s00428-017-2263-3 article EN cc-by Virchows Archiv 2017-11-13

Aim . The aim of this literature review is to generalize existing approaches the pathogenetic treatment gastritis as a basis for prevention gastric cancer, well submit resolution scientific symposium that brought together gastroenterologists from number CIS countries. Background H. pylori infection widespread in proportion infected adults population ranges 60 % over 90 %. This causes high incidence chronic and other diseases associated with pylori. In 2012, cancer was recognized 3rd leading...

10.22416/1382-4376-2018-28-4-7-14 article EN cc-by-nc-nd Russian Journal of Gastroenterology Hepatology Coloproctology 2018-09-01

Gluten-dependency of clinical manifestations, serological and histological abnormalities is the key feature celiac disease (CD) [1].That means, that in most CD patients, all symptoms as well mucosal atrophy are potentially reversible after gluten exclusion based on this fact, gluten-free diet (GFD) main treatment option.Classical conception could be described presence symptoms, CDmarkers intestinal mucosa which resolve GFD reappear renewal intake or continue to exist patients a...

10.12691/ijcd-2-1-9 article EN International Journal of Celiac Disease 2016-05-05
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