A5027834011- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Pancreatitis Pathology and Treatment
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Gut microbiota and health
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Veterinary medicine and infectious diseases
- Microscopic Colitis
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Digestive system and related health
- Clostridium difficile and Clostridium perfringens research
- Healthcare Systems and Public Health
- COVID-19 Clinical Research Studies
- Pharmacological Effects of Natural Compounds
- Alcohol Consumption and Health Effects
- Mycobacterium research and diagnosis
- Pancreatic and Hepatic Oncology Research
- Intestinal and Peritoneal Adhesions
Ministry of Health of the Russian Federation
2016-2025
Moscow State University of Medicine and Dentistry
2015-2024
Chinese University of Hong Kong
2023
Sechenov University
2022
Sanofi (United States)
2022
Sanofi (Germany)
2022
Ministerium für Soziales und Integration Baden-Württemberg
2022
Sanofi (Italy)
2022
Medizinisch Wissenschaftliche Verlagsgesellschaft (Germany)
2022
Endocrinology Research Center
2022
The microbial community of the human gut has a crucial role in sustaining host homeostasis. High-throughput DNA sequencing delineated structural and functional configurations metagenomes world populations. microbiota Russian population is particular interest to researchers, because Russia encompasses uniquely wide range environmental conditions ethnogeographical cohorts. Here we conduct shotgun metagenomic analysis samples from 96 healthy adult subjects, which reveals novel structures....
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Aim . Current recommendations of the Russian Gastroenterological Association are developed to acquaint medical practitioners with modern diagnostics, treatment and trends in rational drug therapy for gastroesophageal reflux disease (GERD). General provisions Incidence rate GERD Federation varies from 11.3 23.6%. is diagnosed history laboratory examination evidence. Esophagogastroduodenoscopy (EGDS) allows detection esophagitis various severity cylindrical epithelial metaplasia esophagus. The...
The purpose of the first multidisciplinary Consensus: to comprehensively analyze pathophysiological, clinical, and pharmacotherapeutic aspects syndrome increased epithelial permeability (SPEP) as one basic mechanisms development human pathology. Consensus presents structure three main levels cytoprotection: preepithelial, subepithelial, intercellular tight contacts in tissues endothelium is considered detail. clinical sections are devoted role SPEP diseases digestive system,...
Aim . These clinical recommendations present up-to-date methods for the diagnosis and treatment of peptic ulcer. The are intended gastroenterologists general practitioners. General provisions. Peptic ulcer (PU) represents a chronic relapsing disease occurring with alternating periods exacerbation remission. main manifestation is formation defect (ulcer) in wall stomach duodenum. Most cases pathogenetically associated infection H. pylori PU can be an independent or represent symptomatic...
Aim . Current clinical recommendations accentuate current methods for the diagnosis and treatment of irritable bowel syndrome (IBS). Key points. IBS is a functional disorder manifested with recurrent, at least weekly, abdominal pain following attributes (any two leastwise): link to defecation, its frequency or stool shape. The symptoms are expected persist minimum three months in total six-month follow-up. Similar other gastrointestinal (GI) disorders, can be diagnosed basing on patient...
Aim: present clinical guidelines, aimed at general practitioners, gastroenterologists, cardiologists, endocrinologists, comprise up-to-date methods of diagnosis and treatment non-alcoholic fatty liver disease. Key points. Nonalcoholic disease, the most wide-spread chronic is characterized by accumulation fat more than 5 % hepatocytes presented two histological forms: steatosis nonalcoholic steatohepatitis. Clinical guidelines provide current views on pathogenesis disease as a multisystem...
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The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global healthcare, underscoring importance of exploring virus's effects on infected individuals beyond treatments and vaccines. Notably, recent findings suggest that can infect gut, thereby altering gut microbiota. This study aimed to analyze microbiota composition differences between patients experiencing mild severe symptoms. We conducted 16S rRNA metagenomic sequencing fecal samples from 49 43 cases upon...
Objective The concept of using naturally occurring compounds such as polyenylphosphatidylcholine (PPC) an adjunctive therapy to treat non-alcoholic fatty liver disease (NAFLD) and alleviate or reverse hepatic steatosis appears a very attractive option for protection. We aim evaluate if PPC can effectively improve the ultrasonographic features NAFLD in routine clinical practice Russian patients with cardiometabolic comorbidities. Design This 24-week, observational, prospective study was...
Aim. The clinical guidelines are intended to supplement specialty decision-making for improved aid quality in patients with gastritis and duodenitis though acknowledging the latest evidence principles of evidencebased medicine. Key points. Gastritis is an inflammatory disease stomach mucosa, a separate definition acute chronic gastritis. Chronic cohort diseases uniting typical morphology persistent infiltration, impaired cellular renewal emergent intestinal metaplasia, atrophy epithelial...
Objective Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal results function tests. Earlier research showed that polyenylphosphatidylcholine (PPC) has hepatoprotective effects and thus can be used for treatment NAFLD prevention its progression. Accordingly, aim this observational study was to evaluate if PPC administered as adjunctive therapy in routine clinical practice effectively improve tests Russian patients with associated metabolic comorbidities. Design A...
Abstract Background The recent data on the prevalence of Helicobacter pylori ( H. ) infection in Russia are limited. aim study was to compare ambulatory settings 2017 and 2019 years. Materials Methods Subjects visiting primary care centers were invited take part study. status assessed by 13 C‐urea breath test (UBT). Data subjects' demography, previous treatment exposure, place residence collected all federal districts calendar years processed centrally. Results 19,875 subjects available for...
The present paper aims to systematize data concerning the prevalence and risk of dental erosion (DE) in adult patients with gastroesophageal reflux disease (GERD) compared controls.Core electronic databases, i.e., MEDLINE/PubMed, EMBASE, Cochrane, Google Scholar, Russian Science Citation Index (RSCI), were searched for studies assessing DE GERD publication dates ranging from 1 January 1985 20 2022. Publications detailed descriptive statistics (the total sample size GERD, controls (if...
The article analyzes modern scientific publications on plant-based meat substitutes. authors discuss a growing interest in diets and alternatives the prospects of using soy-based products. Objective. To analyze substitutes, including issues their contents, production, safety. Materials Methods. literature search analysis were conducted MedLine/PubMed, Cochrane, Google Scholar, RSCI, WHO, Food Agriculture Organization United Nations (FAO) databases for 2010—2024. Results. review shows that...
The majority of metagenomic studies are based on the study bacterial biota. At same time, COVID-19 pandemic has prompted interest in both individual fungal pathogens and communities (i.e., mycobiome) as a whole. Here, this work, we investigated human gut mycobiome during COVID-19. Stool samples were collected from patients at two time points: admission to hospital (the first point) discharge second point). results revealed that Geotrichum sp. is more represented group with Therefore,...
Aim. To determine the trends of primary antibiotic resistance Helicobacter pylori strains isolated from patients living in Moscow. Materials and methods. As part a clinical laboratory study, 123 gastric biopsy specimens H. pylori-infected were analyzed 2015 to 2024. infection was verified by rapid urease test 13C-urease breath test. The anaerobic culture technique used. After identifying pure culture, its susceptibility four antibacterial agents (amoxicillin – AMC, clarithromycin CLR,...
Aim : to present the results of an Expert Consensus on standardization indications for surgical treatment gastroesophageal reflux disease (GERD). Materials and methods . The issues GERD were discussed by 39 experts – leading gastroenterologists surgeons from 7 cities Russia, representing 17 institutions. list questions discussion was formed initiative group sent experts. reviewed recent literature, including existing clinical guidelines consensuses, assessed evidence base suggested...
Aim . The clinical guidelines are intended to provide information support for making decisions by gastroenterologists, general practitioners and internists that will improve the quality of medical care patients with non-alcoholic fatty liver disease, taking into account latest data principles evidence-based medicine. Key points Clinical contain about current views on etiology, risk factors pathogenesis nonalcoholic peculiarities its course. Also given recommendations methods laboratory...