A5047447973- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Pediatric health and respiratory diseases
- Dental materials and restorations
- Infant Nutrition and Health
- Medical and Biological Sciences
- Dental Research and COVID-19
- Dental Radiography and Imaging
- Oral Health Pathology and Treatment
- Engineering Technology and Methodologies
- Legal and Regulatory Analysis
- Oral health in cancer treatment
- Photodynamic Therapy Research Studies
- Dental Implant Techniques and Outcomes
- Dental Trauma and Treatments
- Probiotics and Fermented Foods
- Laser Applications in Dentistry and Medicine
- Digestive system and related health
- Dental Anxiety and Anesthesia Techniques
- Salivary Gland Disorders and Functions
- Healthcare Systems and Public Health
- Medical and Biological Ozone Research
- Bone Tissue Engineering Materials
- Hydrogen's biological and therapeutic effects
- Medical Device Sterilization and Disinfection
Moscow State University of Medicine and Dentistry
2016-2024
Ministry of Health of the Russian Federation
2019-2024
Aim. To determine the trends of primary antibiotic resistance Helicobacter pylori strains isolated from patients living in Moscow. Materials and methods. As part a clinical laboratory study, 123 gastric biopsy specimens H. pylori-infected were analyzed 2015 to 2024. infection was verified by rapid urease test 13C-urease breath test. The anaerobic culture technique used. After identifying pure culture, its susceptibility four antibacterial agents (amoxicillin – AMC, clarithromycin CLR,...
The study reveals the polymer-crosslinker interactions and functionality of hydrophilic nanofibers for antibacterial wound coatings. Coaxial electrospinning leverages a drug encapsulation protocol core-shell fiber composite with core derived from polyvinyl alcohol polyethylene glycol amorphous silica (PVA-PEG-SiO2), shell originating graphene oxide (PVA-GO). Crosslinking GO SiO2 initiates hydrogel transition upon contact moisture, which aims to optimize release. effect hydrogel-inducing...
BACKGROUND: Autogenous material is currently one of the most common and effective materials used for bone grafting. In recent years, based on extracted teeth have attracted attention. When analyzing modern articles, all authors agree that before using autogenous dentinal material, it necessary to carry out antiseptic treatment prevent possible complications.
 AIM: A comparison was made various agents blocks with subsequent osteoplastic operations in pre-implantation period.
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Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became main cause of tooth loss in adult population. Herbal medicines have a variety pharmacological properties, so development introduction new forms for treatment inflammatory is an urgent task today. Purpose – experimental evaluation effectiveness use herbal “Tonzinal” “CM-1” relation to priority pathogenes. Materials methods: studies, basis experiment was system cultivation microorganisms real time...
Aim . To determine possible alternative algorithms for root canal disinfection through the combined use of chemical and physiotherapeutic irrigation techniques under in vitro conditions. Materials methods Single-root teeth removed according to orthodontic indications were used as a substrate formation biofilm. The mixed biofilm is carried out several stages, successively introducing following strains: Streptococcus sanguinis; Fusobacterium nucleatum; Porphyromonas gingivalis. Cultivation was...
Introduction. Lactoferrin is a cationic monomeric glycoprotein produced by acinar cells and glands, present in different places of the mucous membrane concentrations. In connection with development various variants hygienic medicinal products for treatment inflammatory diseases oral cavity based on lactoferrin, there was need an objective assessment its antibacterial antibiofilms properties, followed analysis preservation activity isolation this protein from substrate storage.Aim - to...
Background. The widespread global increase in the incidence of periodontitis and role its pathogens comorbid pathology systemic complications determines need to create new molecular genetic systems for diagnosis use metagenomic bioinformatic analysis methods. Aims methods microbiological genodiagnostics prove etiological key periodontal Filifactor alocis Porphyromonas gingivalis, characterizing degree progression chronic periodontitis, association with a pathological process (type 2 diabetes...
В статье обсуждаются возможности применения фитокомпозиционных сборов в аспекте проведения лечебных и профилактических мероприятий полости рта после хирургического, химиолучевого ортопедического этапов лечения при онкологических заболеваниях челюстно-лицевой области. Цель исследования — экспериментальное обоснование противомикробной эффективности предложенной фитокомпозиции сравнении с известной отношении консорционных групп приоритетных микробных агентов гнойного воспаления коррекции...
As a result of the study, it was found that removal dental plaque using low-frequency ultrasound and ozonized contact medium in chronic generalized catarrhal gingivitis young people can significantly improve state microbiocenosis gingival sulcus. The preservation main resident species is noted, occasional transient disappear frequency isolation aggressive representatives beta-hemolytic streptococci periodontopathogenic decreases. When ozonated water for deposits, efficiency eradication...
Relevance. Development of a chronic periodontal disease is associated with forming microbic biofilms therefore the research anti-biofilm activity drugs allows to expand possibilities their effective use for treatment. Purpose . Determination antimicrobic components (ciprofloxacin, tinidazolum) combined drug (Сiphran ST) on planktonic and biofilm forms pathogens in comparison amoxicillin/clavulanate. Materials methods The pilot study influence executed technique automated cultivation vitro...
The aim of this study was to conduct a clinical and laboratory evaluate the effectiveness endodontic root canal treatment using self-adapting files system (SAF) in complex patients with chronic apical periodontitis. 3% sodium hypochlorite solution used as irrigation agent all groups which included 20 treated conventional manual tools, 21 receiving ultrasonic activation irrigant 26 SAF system. Root biofilm structure studied by scanning electron microscopy (SEM) Quantum 3D microscope (USA)....
The study is devoted to the of effect water ozonated with help short-wave ultraviolet radiation, used in removal dental plaque and hydromassage gums, on microbiota periodontal pockets.Examination treatment 102 patients aged 35–55 years a diagnosis chronic generalized periodontitis moderate severity was carried out. results microbiological studies indicate high efficiency using radiation gums complex severity. pockets after use ozonized showed significant decrease frequency detection...
The aim of the work was to study antibacterial effectiveness anodic dissolution copper electrodes in endodontic treatment teeth with root canals obliterated by more than half length root. included two stages: experimental and clinical. In an using automatic cultivation microorganisms liquid nutrient media, it found that a silver-copper electrode effective respect clinical isolate P. Intermedi C. Albicans, as well mixed culture pathogenic Streptococcus sanguis + Enterococcus faecium –...
BACKGROUND: One of the possible ways to improve quality dental treatment with obliterated root canals is use transcanal direct current exposure. AIM: The aim study was investigate comparative antibacterial activity anodic dissolution copper and silver-copper electrodes used in endodontic teeth experiment. MATERIALS AND METHODS: An experimental performed by implementing a technique for automatic cultivation microorganisms liquid culture media. We clinical isolates individual strains bacteria...
Relevance. Despite the broader indications for use of fluoroquinolones and imidazoles in dentistry, particularly complex treatment periodontitis, sensitivity principal causative agents specifically anaerobic periodontopathogens, remains inadequately studied. Purpose. Is to justify a combination fluoroquinolone (ciprofloxacin) nitroimidazole (tinidazole) chemotherapeutic using modern vitro culture monitoring methods. To provide rationale from group nitroimidazoles utilising contemporary...
Во многих областях медицины применяется метод фотодинамической терапии (ФДТ). Он основан на доставке фотосенсибилизаторов (ФС) в патологические клетки и облучении их светом с длиной волны диапазоне максимального поглощения ФС, что приводит к избирательной клеточной гибели. Актуальным остается вопрос создания таких форм которые обеспечат его максимально эффективную доставку внутрь клеток. Нами разработана новая липосомная форма ФС основе куркуминоидов, повышающая биодоступность. Исследована...
Изучали особенности изменения антимикробного действия фитопрепаратов в комплексе с белком лактоферрином отношении микробных культур. Проверяли гипотезу о возможности профилактического применения данного комплекса патогенов, инициирующих развитие инфекционных заболеваний полости рта. Заранее подготовленную бактериальную взвесь инокулировали питательный бульон предварительным добавлением лактоферрина, а также без него, и добавляли исследуемые образцы фитокомпозиций. В ходе автоматического...
The assessment of the effect disinfectants on microbiota and rationale for choice drugs processing dentures prostheses themselves remains open needs to be carefully studied. For example, chemical preparations group quaternary ammonium derivatives (HR) mixed microbial biofilms formed by representatives oral has not been studied sufficiently, despite their wide practical use. purpose is carry out a comparative in vitro activity relation sanitary significant strains microorganisms number...
Relevance. Determining the antimicrobial activity of disinfectants and their impact on conditionally pathogenic microbiota (CPM), as well justifying selection agents for treating dental impressions prostheses, remains an unresolved issue requiring thorough research. The effects quaternary ammonium compounds (QAC) various microorganisms, particularly regarding effective dilution in practice, are not well-studied despite widespread use. Objective. To compare alkaline combined disinfectants,...
The modulation of the composition oral microbiome in cancer patients is a significant approach to preventing and managing complications from chemotherapy radiation. use mouthwashes first treatment option rehabilitate these patients. Aim: This study evaluated characteristics impact phytocomplexes on dynamics formation mixed microbial consortium comprising potential agents infectious oncological processes. Methods: work carried out an experimental assessment antimicrobial properties ‘Mukosept’...
Совокупность прочностных характеристик титановых сплавов, в частности Ti6Al4V, и выраженные биоактивные свойства покрытия из оксида титана представляют значительный интерес для их совместного использования медицинских конструкциях, что обусловливает необходимость изучения антиадгезивных антимикробных свойств. Приоритетное значение данная проблема приобретает при протезировании суставов (тазобедренного, коленного), сложном челюстно-лицевой области (при огнестрельных осколочных ранениях), а...
Laboratory rationale of application a complex effect ultrasound treatment, and photo-activated disinfection in experiments vitro using strains anaerobic microaerophilic microorganisms isolated from patients with chronic forms pulpitis periodontitis.Microbiologic study root canal was carried out bacteriologic method (2 species obligatory-anaerobic 2 -microaerophilic streptococci). Evaluation the treatment complexwith system on microflora bioreactor. Study biofilms tooth (52 individuals)...
The aim of the work was to study antioxidant efficiency anodic dissolution silver-copper and copper electrodes, cases near-canal endodontic effects in Tocom disease, relation mixed cultural transgenic pathogens infected with root diseases when examining chronic forms pulpitis. results showed that both electrodes has a pronounced and, general, unidirectional antibacterial effect. It found electrode more effect on cultures pathogenic microorganisms S. constellatus + F. nucleatum Streptococcus...