A5082957093- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Oral Health Pathology and Treatment
- Dental Research and COVID-19
- Salivary Gland Disorders and Functions
- Dental Radiography and Imaging
- Orthopedic Infections and Treatments
- Osteomyelitis and Bone Disorders Research
- Infective Endocarditis Diagnosis and Management
- Laser Applications in Dentistry and Medicine
- Sinusitis and nasal conditions
- Dental Implant Techniques and Outcomes
- Pediatric health and respiratory diseases
- Medical and Biological Sciences
- HIV/AIDS oral health manifestations
- Engineering Technology and Methodologies
- Photodynamic Therapy Research Studies
- Infectious Diseases and Tuberculosis
- Human Health and Disease
- Dental Anxiety and Anesthesia Techniques
- Biochemical effects in animals
- Bacterial Identification and Susceptibility Testing
- Infant Nutrition and Health
- Bone Tissue Engineering Materials
Moscow State University of Medicine and Dentistry
2008-2024
Ministry of Health of the Russian Federation
2020-2024
Creative Commons
2019
Presents a modern understanding of the role periodontophatogenic bacteria types: Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans), Tannerella forsythia (Bacteroides forsythus) and Porphyromonas gingivalis as indicators periodontitis emergence development risk. Therminological definitions are given factors, markers risk periodontium inflammatory diseases that show level importance their association with disease well quantitative evaluation these associations.
The study reveals the polymer-crosslinker interactions and functionality of hydrophilic nanofibers for antibacterial wound coatings. Coaxial electrospinning leverages a drug encapsulation protocol core-shell fiber composite with core derived from polyvinyl alcohol polyethylene glycol amorphous silica (PVA-PEG-SiO2), shell originating graphene oxide (PVA-GO). Crosslinking GO SiO2 initiates hydrogel transition upon contact moisture, which aims to optimize release. effect hydrogel-inducing...
The aim of this study is to the colonization subgingival biofilm (SGB) with periodontopathogenic bacteria species and endothelium-dependent vasodilation in patients coronary heart disease concomitant periodontitis.Forty-five cardiovascular diseases (CVDs) were examined - 28 women (62%) 17 men (38%) aged 53-76 years, including 15 acute myocardial infarction (AMI), exertional angina (pectoris), chronic periodontitis (CP) without CVD. Dental cardiological health conditions determined, a...
The aim of the study was development approaches to improve effectiveness antibiotic therapy in dental practice on basis determining sensitivity pathogenic microorganisms antibiotics different groups.The included determination microbial complexes from wound exudate periodontal pocket and apical abscess macrolides, quinolones, penicillins, lincosamides 5-nitroimidazole. A survey dentists clinics patients identify cause frequency use possible adverse reactions also conducted.Dentists prefer...
Aim. Comparative study of frequency detection genetic markers resistance to antibiotics forming in anaerobic bacteria under the conditions mixed biofilms a clinical setting and comparison data phenotypic genotypic methods study. Materials methods. 66 strains biofilm with PCR were studied: Streptococcus sanguinis, salivarius, Staphylococcus aureus, epidermidis, Enterococcus faecalis, Klebsiella pneumoniae, Pseudomonas aeruginosa pathogens - Porphyromonas gingivalis, Tannerella forsythia,...
Relevance . Plastic and reconstructive surgery of the missing outer ear is not always successful may cause complications. Prosthetic reconstruction using silicone ectoprostheses (epitheses) an alternative solution to this problem. Purpose – study aimed verify clinical microbiological protocol prosthetic rehabilitation patients with a auricle temporary epitheses during implant osseointegration placed for final magnet-bar retention system assessment effe ctiveness. Materials methods The...
Aim. To determine the relationship between surface roughness and topography of basic dental polymethyl methacrylate polymer polished by different methods microbial adhesion microorganisms (Porphyromonas gingivalis, Fusobacterium nucleatum Streptococcus sanguis) fungi (Candida albicans) causing periodontal diseases. Methods. Surface was studied atomic force microscopy; microbiological were used to study bacteria Candida diseases surfaces samples methods. Results. It shown that sanguis had...
Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became main cause of tooth loss in adult population. Herbal medicines have a variety pharmacological properties, so development introduction new forms for treatment inflammatory is an urgent task today. Purpose – experimental evaluation effectiveness use herbal “Tonzinal” “CM-1” relation to priority pathogenes. Materials methods: studies, basis experiment was system cultivation microorganisms real time...
Aim . To determine possible alternative algorithms for root canal disinfection through the combined use of chemical and physiotherapeutic irrigation techniques under in vitro conditions. Materials methods Single-root teeth removed according to orthodontic indications were used as a substrate formation biofilm. The mixed biofilm is carried out several stages, successively introducing following strains: Streptococcus sanguinis; Fusobacterium nucleatum; Porphyromonas gingivalis. Cultivation was...
Background. The widespread global increase in the incidence of periodontitis and role its pathogens comorbid pathology systemic complications determines need to create new molecular genetic systems for diagnosis use metagenomic bioinformatic analysis methods. Aims methods microbiological genodiagnostics prove etiological key periodontal Filifactor alocis Porphyromonas gingivalis, characterizing degree progression chronic periodontitis, association with a pathological process (type 2 diabetes...
Relevance. Development of a chronic periodontal disease is associated with forming microbic biofilms therefore the research anti-biofilm activity drugs allows to expand possibilities their effective use for treatment. Purpose . Determination antimicrobic components (ciprofloxacin, tinidazolum) combined drug (Сiphran ST) on planktonic and biofilm forms pathogens in comparison amoxicillin/clavulanate. Materials methods The pilot study influence executed technique automated cultivation vitro...
The aim of the work was to study antibacterial effectiveness anodic dissolution copper electrodes in endodontic treatment teeth with root canals obliterated by more than half length root. included two stages: experimental and clinical. In an using automatic cultivation microorganisms liquid nutrient media, it found that a silver-copper electrode effective respect clinical isolate P. Intermedi C. Albicans, as well mixed culture pathogenic Streptococcus sanguis + Enterococcus faecium –...
BACKGROUND: One of the possible ways to improve quality dental treatment with obliterated root canals is use transcanal direct current exposure. AIM: The aim study was investigate comparative antibacterial activity anodic dissolution copper and silver-copper electrodes used in endodontic teeth experiment. MATERIALS AND METHODS: An experimental performed by implementing a technique for automatic cultivation microorganisms liquid culture media. We clinical isolates individual strains bacteria...
Изучали особенности изменения антимикробного действия фитопрепаратов в комплексе с белком лактоферрином отношении микробных культур. Проверяли гипотезу о возможности профилактического применения данного комплекса патогенов, инициирующих развитие инфекционных заболеваний полости рта. Заранее подготовленную бактериальную взвесь инокулировали питательный бульон предварительным добавлением лактоферрина, а также без него, и добавляли исследуемые образцы фитокомпозиций. В ходе автоматического...
Relevance. Determining the antimicrobial activity of disinfectants and their impact on conditionally pathogenic microbiota (CPM), as well justifying selection agents for treating dental impressions prostheses, remains an unresolved issue requiring thorough research. The effects quaternary ammonium compounds (QAC) various microorganisms, particularly regarding effective dilution in practice, are not well-studied despite widespread use. Objective. To compare alkaline combined disinfectants,...
Совокупность прочностных характеристик титановых сплавов, в частности Ti6Al4V, и выраженные биоактивные свойства покрытия из оксида титана представляют значительный интерес для их совместного использования медицинских конструкциях, что обусловливает необходимость изучения антиадгезивных антимикробных свойств. Приоритетное значение данная проблема приобретает при протезировании суставов (тазобедренного, коленного), сложном челюстно-лицевой области (при огнестрельных осколочных ранениях), а...
Laboratory rationale of application a complex effect ultrasound treatment, and photo-activated disinfection in experiments vitro using strains anaerobic microaerophilic microorganisms isolated from patients with chronic forms pulpitis periodontitis.Microbiologic study root canal was carried out bacteriologic method (2 species obligatory-anaerobic 2 -microaerophilic streptococci). Evaluation the treatment complexwith system on microflora bioreactor. Study biofilms tooth (52 individuals)...
The article presents an overview of the use photodynamic therapy in modern dentistry based on literature sources. Various types photosensitizers are presented, action which has a good effect course process periodontal pockets. conclusion is made about vantages using this method treatment inflammatory diseases, as well microbiota, positive patients.
The aim of the work was to study antioxidant efficiency anodic dissolution silver-copper and copper electrodes, cases near-canal endodontic effects in Tocom disease, relation mixed cultural transgenic pathogens infected with root diseases when examining chronic forms pulpitis. results showed that both electrodes has a pronounced and, general, unidirectional antibacterial effect. It found electrode more effect on cultures pathogenic microorganisms S. constellatus + F. nucleatum Streptococcus...