A5001874084- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Dental Research and COVID-19
- Oral Health Pathology and Treatment
- Dental Radiography and Imaging
- Medical and Biological Sciences
- Pediatric health and respiratory diseases
- Sinusitis and nasal conditions
- Infective Endocarditis Diagnosis and Management
- Dental materials and restorations
- Oral health in cancer treatment
- Salivary Gland Disorders and Functions
- Dental Implant Techniques and Outcomes
- Laser Applications in Dentistry and Medicine
- HIV/AIDS oral health manifestations
- Orthopedic Infections and Treatments
- Infant Nutrition and Health
- Engineering Technology and Methodologies
- Otolaryngology and Infectious Diseases
- Osteomyelitis and Bone Disorders Research
- Dental Trauma and Treatments
- Photodynamic Therapy Research Studies
- Medical and Biological Ozone Research
- Infectious Diseases and Tuberculosis
- Dental Health and Care Utilization
Moscow State University of Medicine and Dentistry
2014-2024
Ministry of Health of the Russian Federation
2017-2024
Clinical Hospital No. 8
2018
State Research Institute of Highly Pure Biopreparations
2018
First Pavlov State Medical University of St. Petersburg
2018
National Research Institute of Public Health named after N.A. Semashko
2000
Aim. To determine the trends of primary antibiotic resistance Helicobacter pylori strains isolated from patients living in Moscow. Materials and methods. As part a clinical laboratory study, 123 gastric biopsy specimens H. pylori-infected were analyzed 2015 to 2024. infection was verified by rapid urease test 13C-urease breath test. The anaerobic culture technique used. After identifying pure culture, its susceptibility four antibacterial agents (amoxicillin – AMC, clarithromycin CLR,...
Presents a modern understanding of the role periodontophatogenic bacteria types: Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans), Tannerella forsythia (Bacteroides forsythus) and Porphyromonas gingivalis as indicators periodontitis emergence development risk. Therminological definitions are given factors, markers risk periodontium inflammatory diseases that show level importance their association with disease well quantitative evaluation these associations.
Since periodontitis and type 2 diabetes mellitus are complex diseases, a thorough understanding of their pathogenesis requires knowing the relationship these pathologies with other disorders environmental factors. In this study, representability subgingival periodontal microbiome 46 subjects was studied by 16S rRNA gene sequencing shotgun pooled samples. We examined 15 patients chronic (CP), associated (CPT2DM), 16 healthy (Control). The severity generalized in both groups (CP CPT2DM)...
Periodontal diseases, especially those with polymicrobial etiology, are often associated type 2 diabetes mellitus, proceeding more severely and affecting the course of mellitus. Recently, this feature has been ability periodontopathogen microflora to cause not only a local infectious process in oral cavity, but also interact human immune system induce various systemic effects. We investigated changes salivary cytokine profile patients chronic periodontitis, observed statistically significant...
Relevance . The current theory of specific bacterial biofilm fails explain why a part patients experiences inflammatory periodontal diseases while the absence detected types “red complex” bacteria. Purpose To clarify microbiological and immunological mechanisms influence viral consortium in etiology pathogenesis diseases. Materials methods Articles survey with elements metanalisis. Literature review based on discussion research results topic 48 sources including 33 foreign ones. Results...
Виром полости рта человека — составная часть микробиома как сообщества микроорганизмов, населяющих полость рта, включает вирусы эукариот, персистирующие в организме человека, и прокариот (бактериофаги). выполняет важнейшие физиологические функции по защите организма от патогенов через контроль состава микробиома, влияние на формирование биопленок, иммуномодулирующие эффекты, играет огромную роль эволюции целом, но нередко служит источником тяжелых заболеваний. Среди вирусов, ведущая развитии...
Aim. Comparative study of frequency detection genetic markers resistance to antibiotics forming in anaerobic bacteria under the conditions mixed biofilms a clinical setting and comparison data phenotypic genotypic methods study. Materials methods. 66 strains biofilm with PCR were studied: Streptococcus sanguinis, salivarius, Staphylococcus aureus, epidermidis, Enterococcus faecalis, Klebsiella pneumoniae, Pseudomonas aeruginosa pathogens - Porphyromonas gingivalis, Tannerella forsythia,...
Relevance . Plastic and reconstructive surgery of the missing outer ear is not always successful may cause complications. Prosthetic reconstruction using silicone ectoprostheses (epitheses) an alternative solution to this problem. Purpose – study aimed verify clinical microbiological protocol prosthetic rehabilitation patients with a auricle temporary epitheses during implant osseointegration placed for final magnet-bar retention system assessment effe ctiveness. Materials methods The...
Gingivitis and periodontitis are chronic inflammatory diseases of the periodontal tissue in humans caused by both environmental genetic factors. The human cytokine genes that regulate immune response may play an important role development these diseases. aim this study is to analyze allele status eight associate it with inflammation humans. A total 296 unrelated males Russian origin were studied. significant association theIL1BandIL6 minor alleles gingivitis was found. In addition, we found...
Aim. To determine the relationship between surface roughness and topography of basic dental polymethyl methacrylate polymer polished by different methods microbial adhesion microorganisms (Porphyromonas gingivalis, Fusobacterium nucleatum Streptococcus sanguis) fungi (Candida albicans) causing periodontal diseases. Methods. Surface was studied atomic force microscopy; microbiological were used to study bacteria Candida diseases surfaces samples methods. Results. It shown that sanguis had...
Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became main cause of tooth loss in adult population. Herbal medicines have a variety pharmacological properties, so development introduction new forms for treatment inflammatory is an urgent task today. Purpose – experimental evaluation effectiveness use herbal “Tonzinal” “CM-1” relation to priority pathogenes. Materials methods: studies, basis experiment was system cultivation microorganisms real time...
Принимая во внимание высокую распространенность частичного и полного отсутствия зубов, а также несовершенство существующих съемных зубных протезов, актуальным направлением современной стоматологии является совершенствование стоматологического ортопедического лечения, в связи с чем был разработан базисный наноструктурный конструкционный материал Нолатек («ВладМиВа», Белгород), основа которого представляет сополимеры полиэфиров метакриловой и диметакриловой кислот, модифицированных композитом,...
3 Федеральное государственное бюджетное
The identification of viable, previously undetectable types of microbes in human atherosclerotic plaques provides new evidence of direct and indirect participation of microbiota in the etiopathogenesis of non-infectious human diseases. Purpose of the study. Isolation determination composition of viable microbes in atherosclerotic comparative analysis with the microbiota oral fluid in patients chronic generalized periodontitis (CP) coronary artery disease (CAD). Materials methods. Fragments...
Aim . To determine possible alternative algorithms for root canal disinfection through the combined use of chemical and physiotherapeutic irrigation techniques under in vitro conditions. Materials methods Single-root teeth removed according to orthodontic indications were used as a substrate formation biofilm. The mixed biofilm is carried out several stages, successively introducing following strains: Streptococcus sanguinis; Fusobacterium nucleatum; Porphyromonas gingivalis. Cultivation was...
Introduction. Lactoferrin is a cationic monomeric glycoprotein produced by acinar cells and glands, present in different places of the mucous membrane concentrations. In connection with development various variants hygienic medicinal products for treatment inflammatory diseases oral cavity based on lactoferrin, there was need an objective assessment its antibacterial antibiofilms properties, followed analysis preservation activity isolation this protein from substrate storage.Aim - to...
В статье обсуждаются возможности применения фитокомпозиционных сборов в аспекте проведения лечебных и профилактических мероприятий полости рта после хирургического, химиолучевого ортопедического этапов лечения при онкологических заболеваниях челюстно-лицевой области. Цель исследования — экспериментальное обоснование противомикробной эффективности предложенной фитокомпозиции сравнении с известной отношении консорционных групп приоритетных микробных агентов гнойного воспаления коррекции...
The review is devoted to the analysis of modern ideas about role bacteria Filifactor alocis in etiology chronic periodontitis. study these bacteria, discovered 1985, complicated by difficulty their detection with cultural methods. According researches, F.alocis good reason can be included red complex periodontal pathogens as most important a synergist such key pathogen Porphyromonas gingivalis, well frequent satellite Fusobacterium nucleatum and, somewhat less frequently, Aggregatibacter...
The aim of the research is choice optimal material for temporary unremovable dentures supported by isoelastic implants. objectives are to study stress-strain state structures consisting milled on implants finite element method and make a comparative assessment microbial adhesion materials long-term in vitro. We made model bridges from three units: supporting first premolar, second molar. examined different elements’ combinations crestal implants, basal natural tooth. compared bridges’...
Means of antiseptic effects on the microflora oral cavity in treatment periodontitis are constantly being improved connection with non-guaranteed results and polyetiology disease. A microbiological study was conducted to substantiate antimicrobial effect drug Krezacin denta different concentrations relation a number periodontopathogens fungi genus Candida. The active substances dent 3% or 5% metronidazole. bioreactor automatic determination optical density culture presence drugs. An...