- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Liver Disease and Transplantation
- Eosinophilic Esophagitis
- Diet, Metabolism, and Disease
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Inflammatory mediators and NSAID effects
- Phonocardiography and Auscultation Techniques
- Therapeutic Uses of Natural Elements
- Child Nutrition and Feeding Issues
- Microscopic Colitis
- Diabetes and associated disorders
- Congenital gastrointestinal and neural anomalies
- Alcohol Consumption and Health Effects
- Medical and Agricultural Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Digestive system and related health
- Clostridium difficile and Clostridium perfringens research
- Human Health and Disease
- Veterinary medicine and infectious diseases
- Liver Diseases and Immunity
- Cardiovascular Syncope and Autonomic Disorders
Moscow State University of Medicine and Dentistry
2013-2023
Ministry of Health of the Russian Federation
2018-2021
Objective The concept of using naturally occurring compounds such as polyenylphosphatidylcholine (PPC) an adjunctive therapy to treat non-alcoholic fatty liver disease (NAFLD) and alleviate or reverse hepatic steatosis appears a very attractive option for protection. We aim evaluate if PPC can effectively improve the ultrasonographic features NAFLD in routine clinical practice Russian patients with cardiometabolic comorbidities. Design This 24-week, observational, prospective study was...
Objective Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal results function tests. Earlier research showed that polyenylphosphatidylcholine (PPC) has hepatoprotective effects and thus can be used for treatment NAFLD prevention its progression. Accordingly, aim this observational study was to evaluate if PPC administered as adjunctive therapy in routine clinical practice effectively improve tests Russian patients with associated metabolic comorbidities. Design A...
Aim . The clinical guidelines are intended to provide information support for making decisions by gastroenterologists, general practitioners and internists that will improve the quality of medical care patients with non-alcoholic fatty liver disease, taking into account latest data principles evidence-based medicine. Key points Clinical contain about current views on etiology, risk factors pathogenesis nonalcoholic peculiarities its course. Also given recommendations methods laboratory...
Purpose of the study. To evaluate effectiveness and safety use rebamipide as part triple eradication therapy (ET) scheme Helicobacter pylori infection. Materials methods. A prospective, randomized comparative study included 94 patients with uncomplicated H. pylori-associated stomach / duodenal ulcer. In process randomization, are divided into three groups depending on intended therapy. The first group (n=36) received a classical first-line ET (omeprazole 20 mg twice day, amoxicillin 1000...
Previous research conducted in Russia showed that the number of patients with non-alcoholic fatty liver disease (NAFLD) and associated metabolic comorbidities is large. We an observational study to describe management NAFLD syndrome Russia.A total 2843 adult from 174 medical sites across 6 federal districts newly diagnosed NAFLD, who had at least one four comorbidities, namely overweight/obesity, hypertension, type 2 diabetes mellitus, hypercholesterolaemia, received phosphatidylcholine...
Peptic ulcer disease (PUD) is a chronic polyetiological recurrent of gastroduodenal region. In most cases, the pathogenesis PU caused by imbalance between aggressive factors and protective gastric or duodenal mucosa. Helicobacter pylori (H. ) infection use non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, are major causative leading to PUD development. 65% ulcers 80% were found be associated with H. infection. turn, NSAIDs account for 30% 15% ulcers. About 0.1–1% all PUs...
The objective of the study was to evaluate prevalence Clostridium difficile-associated diarrhoea (CDAD) among hospitalised patients with antibiotic-associated (AAD) in general and by specific types medical care hospital units. A prospective, cross-sectional, non-interventional, multicentre study. main inclusion criteria were: patient age ≥ 18 years, stay at least 48 h, current antibiotic therapy or within previous 30 days, loose stools (Bristol stool 5–7 frequency 3 ≤ 24 consecutive hours...
Over the past decade, a large number of major studies have been published analysing efficacy including probiotics in eradication therapy regimens Helicobacter pylori (H. pylori) infection. One catalysts for scientific activity this direction is undoubtedly negative trend associated with decrease effectiveness classical observed all over world. To date, results several meta-analyses show that addition certain strains to standard increases efficiency as well reduces frequency side effects...
Aim. To identify the role of impaired motor function gastrointestinal tract (GIT) in overlap functional disorders (FD).
 Materials and methods. Thirty-two abdominal FD patients were followed up, with a predominance women aged 33.76.1 years (75%). Men 31.85.6 25%. All had symptoms GIT established according to Rome IV criteria, endoscopy, ultrasound. In addition, underwent 2-hour pH-metry electromyography organs using bipolar silver electrodes surface area 0.50.6 cm2. The...
Chronic gastritis is a group of chronic diseases that are morphologically characterized by persistent inflammatory infiltrate and impaired cellular turnover with the development intestinal metaplasia, atrophy, epithelial dysplasia in gastric mucosa. Numerous studies have shown Helicobacter pylori (H. pylori) infection absolutely dominant etiological factor CG worldwide. Given this fact, Expert Council latest Maastricht VI 2022 consensus recommended H. to be treated as pathogen, which always...
The purpose of the review is to acquaint general practitioners, therapists, gastroenterologists with possibilities diagnosing functional disorders gastrointestinal tract associated constipation, as well draw attention need for additional examination methods a comprehensive assessment in patients constipation on pathogenesis. Functional an urgent problem today due its prevalence among different age groups, negative impact quality life, variability clinical forms diseases this symptom. modern...