- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Liver Disease Diagnosis and Treatment
- Influenza Virus Research Studies
- Healthcare Systems and Public Health
- Diet, Metabolism, and Disease
- Galectins and Cancer Biology
- Microbial Metabolites in Food Biotechnology
- Cardiovascular Disease and Adiposity
- Inflammatory mediators and NSAID effects
- Esophageal and GI Pathology
- Trace Elements in Health
- Digestive system and related health
- Diabetes and associated disorders
- Gastric Cancer Management and Outcomes
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Orthopedic Infections and Treatments
- Esophageal Cancer Research and Treatment
- Therapeutic Uses of Natural Elements
- Infrared Thermography in Medicine
- Heavy Metal Exposure and Toxicity
- Eicosanoids and Hypertension Pharmacology
Chita State Academy of Medicine
2012-2025
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation
2024
Ministry of Health of the Russian Federation
2018-2023
Helicobacter pylori (HP) is one of the most common infections and recognized as a gastric pathogen in humans, leading to development gastritis all infected individuals. The etiological role HP formation peptic ulcer (PU) cancer (GC) has been noted. prevalence differs different regions, ethnic, social age groups. article summarizes publications on frequency infection countries, changes epidemiological situation world recent years, noted decrease positivity Japan, Korea, China, Australia. Risk...
Justification The participants of the round table on diagnosis and treatment acid - Helicobacter-dependent diseases, held November 20, 2020 at XXIII congress Scientific Society Gastroenterologists Russia within framework XV National Congress Therapists (Authors) having discussed status issue, decided need to harmonize measures pool efforts reduce incidence H. pylori infection by approaching medical community with this Memorandum.
Aim: to assess the effectiveness of mebeverine 200 mg BID in patients with post-cholecystectomy gastrointestinal spasm not requiring surgical treatment. Materials and methods. 218 were included 16 clinical centers 14 cities Russia. All had spasms, treatment received (Duspatalin®) BID. The observational assessment period lasted from moment their inclusion into study up 6 weeks post inlusion. therapy results evaluated using visual analog scales (GPA 11-point numeric rating scale) by patient...
The erosive ulcerous affections of gastrointestinal tract in patients with cardiovascular diseases occur frequently and are conditioned by both ischemia organs digestion against the background reduced cardiac output intake low doses acetylsalicylic acid combined anti-coagulants. bleeding can be first only manifestation gastroduodenal pathology. treatment prevention aspirin-induced gastropathy provides for implementation eradication Helicobacter pylori infection, application cyto-protectors...
Резюме.В статье представлены данные по распространенности гастроэзофагеальной рефлюксной болезни (ГЭРБ
The mechanisms of the gastroesophageal reflux disease (GERD) development and its complications are analyzed on tissue cell levels. That’s why studying polymorphism interleukin (IL) genes is important. Genotypes IL1β-511Т/Т, IL1β31С/С IL1RN2/2 (receptor antagonist IL1) associate with high risk complicated course GERD disease. Researching pro-inflammatory cytokines patients having changes in gastric mucosa it was determined that genotype IL1β-511Т/Т associated deeper local level IL1β....
Background: The aim of our study was to determine the role sphingolipids, which control proliferation and apoptosis, in placenta pregnant women with pregnancy-associated breast cancer (PABC) after chemotherapy compared healthy patients. Methods: We analyzed (by PCR method) gene expression key sphingolipid metabolism enzymes (sphingomyelinases (SMPD1 SMPD3), acid ceramidase (ASAH1), ceramide synthases (CERS 1–6), sphingosine kinase1 (SPHK1), sphingosine-1-phosphate lyase 1 (SGPL1), receptors...
Summary. Thirty three medical records and postmortem examination reports of patients died from influenza A virus (H1N1sw2009) in October November, 2009, the Transbaikal Territory were analyzed. The divided into two groups. first group consisted 22 with obesity second 11 normal body weight. There was no difference between groups age, gender structure, duration disease. Causes death pneumonia progressive respiratory failure. rate acute distress syndrome similar both Thrombosis various...
Objective. To study the frequency of presence Helicobacter pylori (HP), effectiveness eradication treatment, factors that determine failure treatment among doctors in Chita. Material and methods. The involved 164 people aged 19 to 73 years (average age 45.34 ± 13.15 years), including 93 71 patients not related medical activities. HP infection 112 was investigated by determining antigen (AH) feces. 98 were examined for DNA gastric biopsies A2142G, A2143G, T2717C mutations bacterial genome,...
Objective. To determine the prevalence of Helicobacter pylori (HP) in doctors Chita, to identify clinical manifestations infection, endoscopic, ultrasound and morphological changes stomach, conduct eradication treatment with an assessment its effectiveness, resistance HP clarithromycin develop tactics for HP-associated diseases region. Material methods. 70 Chita were examined, including 55 women 15 men, average age 47.04±12.76 years (20 persons 39 younger, 33 40–59 years, 17 people 60 older;...
Aims . To study the CYP2C19(681A/G) polymorphism among population of Trans-Baikal Territory in comparison with data other regions Russia and world. Materials methods. The involved 132 people (81 women 53 men). median age was 47 (18; 72) years. Genotyping 681G/A polymorphic locus CYP2C19 gene performed by polymerase chain reaction. Results. prevalence CYP2C19(681G/G) 105 (79.6%), CYP2C19(681G/A) — 25 (18.9%) CYP2C19(681A/A) 2 participants (1.5%). Allele A position 681 found 14.2%. is less...