A5061416905- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Eosinophilic Esophagitis
- Inflammatory mediators and NSAID effects
- Liver Disease Diagnosis and Treatment
- Infant Health and Development
- Urticaria and Related Conditions
- Pancreatitis Pathology and Treatment
- Anesthesia and Pain Management
- Gastric Cancer Management and Outcomes
- Potassium and Related Disorders
- Liver Diseases and Immunity
- Gallbladder and Bile Duct Disorders
- Microscopic Colitis
- Diet, Metabolism, and Disease
- Digestive system and related health
- Business and Economic Development
- Congenital gastrointestinal and neural anomalies
- Myofascial pain diagnosis and treatment
- Hypertrophic osteoarthropathy and related conditions
- Neuropeptides and Animal Physiology
- Antiplatelet Therapy and Cardiovascular Diseases
- Biliary and Gastrointestinal Fistulas
- Chemical synthesis and pharmacological studies
Federal Almazov North-West Medical Research Centre
2019-2025
Ministry of Health of the Russian Federation
2020-2022
North-Western State Medical University named after I.I. Mechnikov
2013-2019
Northwestern State University
2016
The course of Gastroesophageal reflux disease (GERD), which is a widespread disease, aggravated by combination with other diseases, including functional pathology the gastrointestinal tract, for example, dyspepsia or irritable bowel syndrome (IBS). This affects not only clinical features but also effectiveness GERD therapy, when there are cases incomplete response to proton pump inhibitors (PPIs). And doctor faced choice drugs complex treatment GERD. For in case and IBS it necessary consider...
Introduction. Despite the high prevalence of functional dyspepsia (FD), question effective treatment this pathology remains open. This underlines relevance new approaches in FD and introduction drug Dyspevict® (acotiamide), a prokinetic with mechanism action, into clinical practice to alleviate symptoms improve quality life patients FD. Aim. Evaluate efficacy safety use acotiamide postprandial distress syndrome (PDS). Materials methods . 389 were randomized 1:1 ratio two groups. Patients...
Objective of the Review: to discuss most common adverse events from use non-steroidal anti-inflammatory drugs (NSAID) for GIT: NSAID-induced esophago-, gastroduodeno- and enteropathy, possible management various therapies in order minimize risks this pathology. Key Points. NSAIDs are efficient analgetics products widely used clinical setting. prescribed mostly patients with chronic joint spine conditions. As a lot who take comorbid, they have frequent reactions drugs, including NSAIDs, need...
Gastrointestinal motility disorders can be a leading pathogenetic factor contributing to the development of many common gastroenterological diseases. Motor mechanism both organic pathology (developmental abnormalities, acquired diseases, etc.), and functional gastrointestinal diseases associated with impaired nervous, humoral, metabolic local regulation. (the latter are quite in clinical practice). Correction digestive is determined by an understanding mechanisms its complex regulation,...
Цель обзора: рассмотрение современных представлений о механизмах действия и результатов исследований нимесулида, в частности фармакокинетики лекарственной формы нимесулида с улучшенными характеристиками дезинтеграции, вносящими существенный вклад реализацию лечебного эффекта, а также новых ЦОГ-независимых эффектов нимесулида.Основные положения.К достоинствам следует отнести высокую биодоступность, эффективность обезболивания, выраженный противовоспалительный эффект.Высокая скорость...
Gallstone disease (GSD) is currently one of the most common diseases gastrointestinal tract, especially among people working age, and has a clear tendency to increase expand age range towards rejuvenation. To date, possible links in pathogenesis cholelithiasis have been well studied described, risk factors clinical manifestations which asymptomatic course cholelithiasis, often noted at first latent stage disease, important. It this that preventive conservative treatment allows patients avoid...
Chronic gastritis represents a significant challenge for most clinicians, not only because it is the prevalent disease of digestive system, but also due to morphologic changes induces, which can progress from inflammation atrophy and dysplasia. These are particularly relevant in context cancer prevention. Helicobacter pylori infection recognized as common etiological factor associated with chronic atrophic gastritis. Nevertheless, even successful anti-Helicobacter therapy does always result...
Введение. Последними исследованиями и руководствами неалкогольная жировая болезнь печени признается междисцип-линарной проблемой на стыке гастроэнтерологии, кардиологии эндокринологии. Возросший в последние годы интерес к неалкогольной жировой болезни как самому распространенному хроническому заболеванию определяет эту патологию вносящую вклад развитие прогрессирование сердечно-сосудистых заболеваний сахарного диабета 2-го типа. Проведенные исследования последовательно раскрывают сложные...
Metabolic-associated fatty liver disease or metabolic dysfunction-associated steatotic is a common chronic characterized by increased fat accumulation in the and underlying dysfunction. In occurrence of this disease, cardiometabolic factors are important: dyslipidemia, impaired carbohydrate metabolism, insulin resistance, which increase as dysfunction- associated progresses most often contribute to development cardiovascular pathology. Currently, multisystem with obesity, type 2 diabetes,...
Constipation is a disorder that affects large number of people and has negative impact on quality life. one the common reasons for seeking medical help from an outpatient doctor. The problem constipation can often be multifactorial, with important causes being low fiber in diet, decreased fluid intake physical inactivity. For some patients, not chronic problem, but may occur at point their lives, usually lasts limited period time serious solution to which changes diet lifestyle, or short...
Введение. Гастроэзофагеальная рефлюксная болезнь – многофакторное заболевание, которое достаточно часто встречается в клинической практике. Высокая распространенность, четкая тенденция к увеличению заболеваемости не только России, но и во всех странах мира, хроническое рецидивирующее течение существенное влияние на качество жизни пациентов, сложность их ведения при гастроэзофагеальной рефлюксной болезни, особенно коморбидных выделяют ее среди других видов патологии органов пищеварения....
Nonsteroidal anti-inflammatory drugs (NSAIDs) have a strong analgesic and effects are widely used in clinical practice. Patients with chronic disorders of the joints, particular spine, main consumers NSAIDs. However, risk factors for side-effects should be taken into consideration treatment NSAIDs, especially patients old age. The careful control taking account developing gastrointestinal cardiovascular events is needed.Нестероидные противовоспалительные препараты (НПВП) обладают мощным...
Objective of the Review: To analyse contemporary idea use nonsteroidal anti-inflammatory drugs (NSAIDs) in cardiovascular comorbidities. Key Points. Adverse class-mediated side effects NSAIDs complicate these pathologies. Moderate Nimesulide selectivity is a cause low risks blood pressure destabilization, vascular catastrophes (acute myocardial infarction, stroke), other thrombotic complications recorded clinical trials. Conclusion. These characteristics allow recommending comorbidities,...
Non-alcoholic fatty liver disease (NAFLD) is recognized as an interdisciplinary problem at the intersection of therapy, gastroenterology and endocrinology. In recent years, there has been a significant increase in interest NAFLD accomplice cardiovascular (CVD) type 2 diabetes mellitus (DM2). The article discusses mechanisms development progression diseases depending on risk factors comorbidity, including clinical case. proven clear association with obesity, DM 2, CVD suggests that these...
The prevention of thromboembolism is the leading goal in management atrial fibrillation (AF) patients. Oral anticoagulants (OAC) has been using treatment AF patients for a long time according modern clinical recommendations. Recently, new direct oral (NOAC) have increasingly used and thrombo-embolism However, problem bleeding anticoagulated (primarily gastrointestinal tract) still unresolved. authors analyzed results evidence-based medicine assessing risk with NOACs. (For citation: Bakulin...
It is known that gastritis, gastroduodenitis and peptic ulcer belong to the group of acid-dependent diseases, which occupy a significant proportion among digestive system diseases. Despite use proton pump inhibitors in therapy, discovery an important role H. pylori infection genesis these diseases development eradication schemes, urgency problem persists due formidable complications (bleeding, perforation). The modern therapeutic concept treatment (including gastroduodenitis) provides active...
У статті висвітлено підходи до організації системи державного регулювання фінансового ринку в умовах вітчизняної розбалансованості та неконкурентоспрможності фінансово-кредитної України на міжнародній арені з викривленням ринкових механізмів неефективністю діючих фінансових інститутів; розглянуто механізм Україні реформування кризового стану економіки країни; розкрито можливості запровадження мегарегулятора розрізі Концепції перебудовою інфраструктури корпоративного управління для...
In recent years, functional disorders of the gastrointestinal tract (GIT) are quite common. The most significant dyspepsia (FD), which is widespread in population. addition, clinical practice outpatient doctors, proportion combined variants or overlap several types a combination with organic pathology has increased. So, according to systematic reviews, course gastroesophageal reflux disease (GERD) and FD occurs at least one third patients. At same time, changes picture GERD, complicates...