С. А. Алексеенко
A5068383279- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Diet and metabolism studies
- Atomic and Subatomic Physics Research
- Inflammatory Bowel Disease
- Probiotics and Fermented Foods
- Metabolism and Genetic Disorders
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal disorders and treatments
- Geomagnetism and Paleomagnetism Studies
- Microscopic Colitis
- Microbial Metabolites in Food Biotechnology
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Congenital gastrointestinal and neural anomalies
- Magnetic confinement fusion research
- Liver Disease and Transplantation
- Pharmacological Effects of Natural Compounds
- Veterinary medicine and infectious diseases
- Digestive system and related health
Far Eastern State Medical University
2019-2025
Ministry of Health of the Russian Federation
2019-2024
National Medical Association
2021
Research Institute of Fundamental and Clinical Immunology
1997
Russian Academy of Sciences
1972
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The purpose of the first multidisciplinary Consensus: to comprehensively analyze pathophysiological, clinical, and pharmacotherapeutic aspects syndrome increased epithelial permeability (SPEP) as one basic mechanisms development human pathology. Consensus presents structure three main levels cytoprotection: preepithelial, subepithelial, intercellular tight contacts in tissues endothelium is considered detail. clinical sections are devoted role SPEP diseases digestive system,...
INTRODUCTION: The safety of Helicobacter pylori eradication treatments and to what extent adverse events (AEs) influence therapeutic compliance in clinical practice are hardly known. Our aim was assess the frequency, type, intensity, duration AEs, their impact on compliance, for most frequently used “European Registry management.” METHODS: Systematic prospective noninterventional registry European gastroenterologists (27 countries, 300 investigators) management H. infection routine practice....
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Aim. The clinical guidelines are intended to supplement specialty decision-making for improved aid quality in patients with gastritis and duodenitis though acknowledging the latest evidence principles of evidencebased medicine. Key points. Gastritis is an inflammatory disease stomach mucosa, a separate definition acute chronic gastritis. Chronic cohort diseases uniting typical morphology persistent infiltration, impaired cellular renewal emergent intestinal metaplasia, atrophy epithelial...
Aim. The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and internists to advance the treatment prevention of gastroenterological diseases in adults children therapies with probiotics, prebiotics, synbiotics their enriched functional foods. Key points. Probiotics live microorganisms that sustain health host when supplied adequate amounts. Prebiotics include human-indigestible but accessible gut microbiota substances...
Aim . The clinical guidelines are intended to provide information support for making decisions by gastroenterologists, general practitioners and internists that will improve the quality of medical care patients with non-alcoholic fatty liver disease, taking into account latest data principles evidence-based medicine. Key points Clinical contain about current views on etiology, risk factors pathogenesis nonalcoholic peculiarities its course. Also given recommendations methods laboratory...
Aim : bring to the attention of practitioners indications for anti-Helicobacter therapy, methods and procedure diagnostics eradication therapy Н . pylori infection. Key points Chronic gastritis caused by infection, including asymptomatic persons, may be considered as an indication Н. etiological opportunistic screening gastric cancer prevention. Indications, obligatory include peptic ulcer, MALT lymphoma, early (EGC) with endoscopic resection. H. primary 13 C-urea breath test, stool antigen...
The multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group (EHMSG) is conducted in 27 countries Europe. data from Russian part of registry for management pylori infection (European Registry on infection, protocol: “Hp-EuReg”) allows us to analyze real clinical practice diagnosis treatment H. compare it with international recommendations. Materials methods. A comparative analysis entered register research centers “Hp-EuReg”, period 2013...
Aim: to present modern methods of diagnosis and treatment chronic pancreatitis for gastroenterologists, general practitioners physicians. Chronic (CP) is a long-term inflammatory disease the pancreas, manifested by irreversible morphological changes in parenchyma pancreatic ducts, which cause pain and/or persistent impairment function. Current concept on etiology CP reflected TIGAR-O classification. The criteria establishing include typical attacks abdominal clinical laboratory signs...
Aim . To optimize the choice of treatment strategies by physicians and gastroenterologists to improve prevention small intestinal bacterial overgrowth (SIBO) in adults. Key points SIBO is a condition characterized an increased amount and/or abnormal composition microbiota intestine. Clinically, syndrome manifested nonspecific gastroenterological complaints development malabsorption syndrome. Most often, associated with various chronic non- infectious diseases (both gastrointestinal tract,...
Abstract Background Management of Helicobacter pylori ( H. ) infection requires co‐treatment with proton pump inhibitors (PPIs) and the use antibiotics to achieve successful eradication. Aim To evaluate role dosage PPIs duration therapy in effectiveness eradication treatments based on ‘European Registry management’ (Hp‐EuReg). Methods Hp‐EuReg is a multicentre, prospective, non‐interventionist, international registry routine clinical practice management by European gastroenterologists. All...
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Aim: to discuss current views on the clinical significance, diagnostic opportunities, and therapeutic approaches in treatment of small intestinal bacterial overgrowth (SIBO) as an important component gut microbiota function assessment, assess awareness physicians opportunities diagnosis this disease patients Federal districts Russian Federation, well present proceedings Expert Council held December 16, 2023 Moscow. Key points. SIBO is a common syndrome often associated with irritable bowel...
Aim: to optimize outcomes of the treatment and prevention gastrointestinal diseases in adults children. Key points. The Methodological Guidelines contain sections on terminology, classification, mechanisms action, requirements for sale Russian Federation, proving efficacy safety probiotics, prebiotics, synbiotics metabiotics, as well functional foods enriched with them. An overview relevant data allowing include these drugs products an d children is presented. Conclusion. clinical...
Aim. To provide practical recommendations on the use of probiotics for treatment and prevention gastroenterological diseases in adults. General provisions. Probiotics are living microorganisms that benefit health host when administered adequate amounts. The main functions include support colonisation resistance, metabolism food substrates utilisation end metabolites, production necessary macro-organism, as well regulation local adaptive immune responses. can be registered Russian Federation...
Several methods are available to diagnose Helicobacter pylori infection. Our objective was evaluate the tests used for both initial diagnosis and confirmation of eradication after treatment in Europe.The European Registry on management infection is an international, multicentre, prospective, non-interventional registry aiming pylori-infected patients Europe. Countries with at least 100 cases registered from June 2013 April 2021, a validated diagnostic method were analysed. Data quality...
This document was produced with the support of National Medical Association for Study Comorbidities (NASС). In 2021 first multidisciplinary Consensus on pathophysiological and clinical aspects Increased Epithelial Permeability Syndrome published. The proposed guidelines are developed basis this Consensus, by same team experts. Twenty-eight Practical Guidelines Physicians statements were adopted Expert Council using "delphic" method. Such main groups epithelial protective drugs as proton pump...
The human body, like any other, is an intermediate component of the nitrogen cycle in nature. Consuming from external environment form various compounds, body processes it into ammonia - one final products exchange nitrogen-containing substances [1], which removed urea. most active producers are organs with high amino acids and biogenic amines nerve tissue, liver, intestine, muscles. In a state equilibrium, adult consumes releases about 15 g per day, temporary or permanent disruption balance...
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ABSTRACT Background The influence of indications for Helicobacter pylori investigation on prescriptions and effectiveness is unknown. aim the study was to assess impact H. prescriptions, effectiveness, compliance, tolerance. Methods International, prospective, non‐interventional registry management infection by European gastroenterologists (Hp‐EuReg). Treatment‐näive patients registered from 2013 2023 at e‐CRF AEG‐REDCap were analyzed. assessed modified intention‐to‐treat analysis. Results...
Aim: to provide the basic points of Expert Panel Russian Gastroenterological Association with discussion measures improve diagnostics, treatment and management chronic gastritis patients. Key points. In Federation in 2021 more than 30 million patients diagnosed “Gastritis duodenitis” were recorded (K29 accordance International Classification Diseases-10). H. pylori incidence rate population has reduced presently is about 40 %. pattern -associated still dominated though percent after...