Olga P. Nyssen
A5089741986- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Gastric Cancer Management and Outcomes
- Veterinary medicine and infectious diseases
- Eosinophilic Esophagitis
- Celiac Disease Research and Management
- Microscopic Colitis
- Intestinal and Peritoneal Adhesions
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Microbial Metabolites in Food Biotechnology
- Adrenal Hormones and Disorders
- Liver Diseases and Immunity
- Phytochemistry and Bioactive Compounds
- Evaluation and Performance Assessment
- Mental Health via Writing
- Mycobacterium research and diagnosis
- Nosocomial Infections in ICU
- Electronic Health Records Systems
- Colorectal Cancer Treatments and Studies
- Pregnancy and Medication Impact
- Paleopathology and ancient diseases
- Natural Language Processing Techniques
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2016-2025
Universidad Autónoma de Madrid
2011-2025
Hospital Universitario de La Princesa
2011-2025
Instituto de Salud Carlos III
2024
Montavid Thermodynamic Research Group
2020
Medical Research Network
2018
University Gastroenterology
2018
Queen Mary University of London
2013-2014
Amarin (United Kingdom)
2011
The best approach for Helicobacter pylori management remains unclear. An audit process is essential to ensure clinical practice aligned with standards of care.International multicentre prospective non-interventional registry starting in 2013 aimed evaluate the decisions and outcomes H. by European gastroenterologists. Patients were registered an e-CRF AEG-REDCap. Variables included demographics, previous eradication attempts, prescribed treatment, adverse events outcomes. Data monitoring was...
INTRODUCTION: Antibiotic resistance is one of the main factors that determine efficacy treatments to eradicate Helicobacter pylori infection. Our aim was evaluate effectiveness first-line and rescue against H. in Europe according antibiotics resistance. METHODS: Prospective, multicenter, international registry on management (European Registry Management). All infected culture-diagnosed adult patients registered Spanish Association Gastroenterology-Research Electronic Data Capture from 2013...
Aliment Pharmacol Ther 2012; 35: 275–283 Summary Background Ciclosporin has proven to be effective in patients with corticosteroid‐refractory ulcerative colitis (UC). When therapy this drug fails, infliximab can considered avoid colectomy. The efficacy and safety of sequential approach remain unknown. Aim To assess the profile treatment after failure ciclosporin a flare UC. Methods Retrospective review medical records UC who did not respond received salvage within month discontinuing...
Background: Bacterial antibiotic resistance changes over time depending on multiple factors; therefore, it is essential to monitor the susceptibility trends reduce impact effectiveness of various treatments. Objective: To conduct a time-trend analysis Helicobacter pylori antibiotics in Europe. Methods: The international prospective European Registry Management (Hp-EuReg) collected data all infected adult patients diagnosed with culture and antimicrobial testing positive results that were...
INTRODUCTION: The safety of Helicobacter pylori eradication treatments and to what extent adverse events (AEs) influence therapeutic compliance in clinical practice are hardly known. Our aim was assess the frequency, type, intensity, duration AEs, their impact on compliance, for most frequently used “European Registry management.” METHODS: Systematic prospective noninterventional registry European gastroenterologists (27 countries, 300 investigators) management H. infection routine practice....
There has been resurgence in the use of bismuth quadruple therapy (proton pump inhibitor, bismuth, tetracycline and metronidazole) for treating Helicobacter pylori infection thanks to a three-in-one single-capsule formulation.To evaluate effectiveness safety therapy.Data were collected multicentre, prospective registry clinical practice gastroenterologists on management H. infection, where patients registered at Asociación Española de Gastroenterologia REDCap database an electronic case...
Managing Helicobacter pylori infection requires constant decision making, and each is open to possible errors.The aim was evaluate common mistakes in the eradication of H. pylori, based on "European Registry management".European management an international multicentre prospective noninterventional registry evaluating decisions outcomes by European gastroenterologists routine clinical practice.Countries recruiting more than 1000 patients were included (26,340 patients). The most (percentages)...
non-bismuth sequential therapy (SEQ) was suggested as a first-line anti-
Adherence to Helicobacter pylori (H. pylori) eradication treatment is a cornerstone for achieving adequate efficacy.
Abstract Introduction Gastric cancer (GC) is one of the most lethal malignancies worldwide. Helicobacter pylori primary cause GC; therefore, its eradication reduces risk developing this neoplasia. There extensive evidence regarding quadruple therapy with relevance to European population. However, in Latin America, data are scarce. Furthermore, there limited information about rates achieved by antibiotic schemes and American populations. Objective To compare effectiveness standard triple...
Bismuth quadruple therapies (BQTs) including bismuth, a proton pump inhibitor (PPI) and two antibiotics have been shown to be highly effective for treating
Aim: To evaluate the prescriptions patterns, effectiveness, and safety of adding probiotics to Helicobacter pylori eradication therapy, in Europe. Design: International, prospective, non-interventional registry clinical practice European gastroenterologists. Data were collected quality reviewed until March 2021 at AEG-REDCap. The effectiveness was evaluated by modified intention-to-treat analysis, differentiating geographic areas. Adverse events (AE) categorized as mild, moderate, severe....
The management of Helicobacter pylori (H. pylori) infection encompasses different diagnostic and therapeutic procedures. A survey was developed to investigate further factors the clinical practice concerning H. that are currently not collected within European Registry on Management (Hp-EuReg). distributed among Spanish Hp-EuReg investigators, members Gastroenterology Association, through social media. Overall, 128 investigators from all regions participated (79% centers enrolling patients in...
Treatment is indicated for all Helicobacter pylori infections. However, the best approach H. management remains unclear. eradication data from Hp-EuReg on treatment-naive patients in Slovenia 2013 to 2023 were included. The regimens prescribed, number of attempts, effectiveness, adherence, and safety analyzed. effectiveness was assessed by modified intention treat (mITT). Eight Slovenian medical institutions contributed 4016 Hp-EuReg. Of these, 18% did not undergo confirmatory...