Alfredo J. Lucendo
A5056364928- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- Inflammatory Bowel Disease
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- IL-33, ST2, and ILC Pathways
- Gastroesophageal reflux and treatments
- Celiac Disease Research and Management
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Autoimmune and Inflammatory Disorders
- Child Nutrition and Feeding Issues
- Digestive system and related health
- Pregnancy and Medication Impact
- Immunodeficiency and Autoimmune Disorders
- COVID-19 Clinical Research Studies
- Diagnosis and treatment of tuberculosis
- Veterinary medicine and infectious diseases
- Hidradenitis Suppurativa and Treatments
- Clinical Nutrition and Gastroenterology
- Pancreatitis Pathology and Treatment
- Food Allergy and Anaphylaxis Research
- Microbial Metabolites in Food Biotechnology
- Gastrointestinal Bleeding Diagnosis and Treatment
Hospital General de Tomelloso
2016-2025
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2016-2025
Hospital Universitario de La Princesa
2019-2025
Instituto de Salud Carlos III
2018-2025
Centro de Investigación Biomédica en Red
2017-2025
Northwestern University
2024
Cincinnati Children's Hospital Medical Center
2024
Children's Hospital of Philadelphia
2024
Icahn School of Medicine at Mount Sinai
2024
University of Cincinnati
2024
Consensus diagnostic recommendations to distinguish GORD from eosinophilic oesophagitis (EoE) by response a trial of proton pump inhibitors (PPIs) unexpectedly uncovered an entity called 'PPI-responsive oesophageal eosinophilia' (PPI-REE). PPI-REE refers patients with clinical and histological features EoE that remit PPI treatment. Recent evolving evidence, mostly adults, shows at baseline are clinically, endoscopically histologically indistinguishable have significant overlap in terms Th2...
Dupilumab, a fully human monoclonal antibody, blocks interleukin-4 and interleukin-13 signaling, which have key roles in eosinophilic esophagitis.
Background & AimsSwallowed topical-acting corticosteroids are recommended as first-line therapy for eosinophilic esophagitis (EoE). Asthma medications not optimized esophageal delivery sometimes effective, although given off-label. We performed a randomized, placebo-controlled trial to assess the effectiveness and tolerability of budesonide orodispersible tablet (BOT), which allows drug be delivered esophagus in adults with active EoE.MethodsWe double-blind, parallel study 88 EoE Europe....
Abstract Introduction Microscopic colitis is a chronic inflammatory bowel disease characterised by normal or almost endoscopic appearance of the colon, watery, nonbloody diarrhoea and distinct histological abnormalities, which identify three subtypes, collagenous colitis, lymphocytic incomplete microscopic colitis. With ongoing uncertainties new developments in clinical management there need for evidence‐based guidelines to improve medical care patients suffering from this disorder. Methods...
Background: The long-term effects of COVID-19 remain largely unclear. This study aims to investigate post-acute health consequences and mortality one year after hospital discharge. Methods: All surviving adult patients who were discharged admission due acute in the first wave pandemic underwent a comprehensive interview. Functional assessment was performed aged over 65. Clinical records reviewed causes assessed. Results: A total 587 with from hospital, including 266 321 emergency room....
Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder. Swallowed topical-acting corticosteroids are effective in bringing active EoE into remission. However, it not clear whether these drugs for long-term maintenance of remission.We performed double-blind trial to compare the efficacy and safety 2 dosages budesonide orodispersible tablet (BOT) vs placebo maintaining remission EoE. Maintenance was defined as absence clinical histologic relapse no premature withdrawal any reason....
Eosinophilic esophagitis (EE) is an emerging disease caused by dense infiltration of the esophageal epithelium eosinophilic leucocytes. It originated from local hypersensitivity to food or airborne allergens. Although physiopathologic mechanisms illness have not been fully discovered, EE a loss immunologic tolerance esophagus, meaning that it should be considered as active organ. In our study, we investigated capacity using immunohistochemistry and stereology, determine cellular density...