- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- IL-33, ST2, and ILC Pathways
- Gastrointestinal disorders and treatments
- Pediatric health and respiratory diseases
- Child Nutrition and Feeding Issues
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Mast cells and histamine
- Esophageal and GI Pathology
- Noise Effects and Management
- Food Safety and Hygiene
- Urticaria and Related Conditions
- Folate and B Vitamins Research
- Consumer Attitudes and Food Labeling
- Respiratory and Cough-Related Research
- Air Quality and Health Impacts
- Monoclonal and Polyclonal Antibodies Research
- Potassium and Related Disorders
- Insects and Parasite Interactions
- Pharmaceutical industry and healthcare
- Celiac Disease Research and Management
University of Virginia
2016-2025
Johns Hopkins Medicine
2015-2024
Johns Hopkins University
2015-2024
University of Virginia Health System
2019-2022
Virginia Commonwealth University Medical Center
2021
University of Baltimore
2013-2021
Charlottesville Medical Research
2020
Johns Hopkins Hospital
2012
Disease activity and severity of eosinophilic esophagitis (EoE) dictate therapeutic options management, but the decision-making process for determining varies among practitioners. To reduce variability in practice patterns help clinicians monitor clinical course disease an office setting, we aimed to create international consensus scoring index EoE.
Three COVID-19 vaccines have received FDA-authorization and are in use the United States, but there is limited head-to-head data on durability of immune response elicited by these vaccines. Using a quantitative assay we studied binding IgG antibodies BNT162b2, mRNA-1273 or Ad26.COV2.S an employee cohort over span out to 10 months. Age sex were explored as modifiers. Of 234 subjects vaccine cohort, 114 six Ad26.COV2.S. levels measured between seven 20 days after second vaccination similar...
Introduction Eosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This inflammatory disorder affects up to 50 per 100,000 individuals in United States and Europe yet limited treatment options. While transcriptome EoE has been reported, few studies have examined genetics among cohort including both adult pediatric populations. To identify potentially overlooked biomarkers biopsies that may be promising targets for...
Abstract Background Recent studies have shown deposition of immunoglobulin G4 (IgG4) and food proteins in the esophageal mucosa eosinophilic esophagitis (EoE) patients. Our aims were to assess whether co‐localization IgG4 major cow's milk (CMPs) was associated with EoE disease activity investigate enriched proximity deposits. Methods This study included adult subjects ( n = 13) non‐EoE controls 5). Esophageal biopsies immunofluorescence stained for CMPs. Co‐localization paired samples from...
Sauer, Bryan G. MD, MSc, FACG; Barnes, Barrett H. MD; McGowan, Emily C. PhD Author Information