A5031214697- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Hernia repair and management
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Pathogenesis and Treatment of Hiccups
- Cardiovascular Syncope and Autonomic Disorders
- Eosinophilic Disorders and Syndromes
- Diverticular Disease and Complications
- Restless Legs Syndrome Research
- Parkinson's Disease Mechanisms and Treatments
- Transplantation: Methods and Outcomes
- Gastrointestinal disorders and treatments
- Dermatology and Skin Diseases
- Renal function and acid-base balance
- Whipple's Disease and Interleukins
- Musculoskeletal pain and rehabilitation
Hospital Universitario 12 De Octubre
2009-2021
Research Institute Hospital 12 de Octubre
2009-2020
Background & AimsSwallowed topical-acting corticosteroids are recommended as first-line therapy for eosinophilic esophagitis (EoE). Asthma medications not optimized esophageal delivery sometimes effective, although given off-label. We performed a randomized, placebo-controlled trial to assess the effectiveness and tolerability of budesonide orodispersible tablet (BOT), which allows drug be delivered esophagus in adults with active EoE.MethodsWe double-blind, parallel study 88 EoE Europe....
Abstract α‐Synuclein inclusions have been identified in the brain and some parts of enteric nervous system Parkinson's disease cases. We aimed to assess these gastric mucosa samples from patients with symptomatic disease. Random biopsies were performed by gastroscopy 28 29 age‐ sex‐matched controls. Gastroscopy was start enteral levodopa ( l ‐dopa) therapy cases for diagnostic purposes controls (gastroesophageal reflux, anemia, abdominal pain main indications). The clinical definition made a...
Background: High-resolution manometry (HRM) is a breakthrough in the morphological study of gastroesophageal junction (GEJ) and its degrees disruption.Objectives: a) Assessment risk factors involved disruption GEJ patients with reflux (GER) symptoms; b) relationship between type GER demonstrated by 24 hours pH-monitoring; c) identification alterations manometric parameters related to morphology GEJ.Methods: One hundred fifteen symptoms studied HRM classified (type I: Normal; II: Sliding;...
lung transplantation (LTx) is a viable option for most patients with end-stage diseases. Esophageal motor disorders (EMD) are frequent in candidates LTx, but there very little data about changes esophageal motility post-LTx.the aim of our study was to assess by high resolution manometry (HRM) both pre-LTx and six months post-LTx without organ rejection.HRM (Manoscan®) performed 57 post-LTx. HRM plots were analyzed according the Chicago classification 3.0.EMD found 33.3% 49.1% post-LTx,...
Constanza Ciriza-de-los-R?os, Fernando Canga-Rodr?guez-Valc?rcel, David Lora-Pablos, Javier De-La-Cruz-B?rtolo, Isabel Castel-de-Lucas, and Gregorio Castellano-Tortajada. J Neurogastroenterol Motil 2015;21:370-9. https://doi.org/10.5056/jnm14110
Introduction: There exits a great variability in the manometric findings between patients with anal incontinence (AI) and healthy subjects.The correlation pressures of canal AI is not exact by wide rank normal values.Objectives: Prospective study to evaluate differences rectal sensitivity AI, chronic constipation (CC) subjects.Material methods: Ninety four 36 CC 15 subjects were included.The following data obtained: age, sex, resting pressure, length (ACL), squeeze maximum pressure (SMP),...
IntroductionActivation of mast cells causes alteration in epithelial and neuromuscular function, is involved visceral hypersensitivity dysmotility gastrointestinal functional disorders. ObjectivesPrimary: Evaluate differences basal serum tryptase (BST) between patients with irritable bowel syndrome (IBS) healthy controls.Secondary: BST depending on IBS subtype (diarrhea: IBS-D; constipation: IBS-C), comorbidities correlations severity quality life. Material methodsProspective control-case...
Chronic constipation is a complex and multifactorial problem. We present the case of 53-year-old woman with life-long complicated by solitary rectal ulcer. In these cases it always necessary to evaluate presence evacuation disorder, both functional (dyssynergic defecation) anatomical. An exhaustive clinical history physical examination that includes dynamic are essential. Currently, anorectal manometry study choice for evaluation accompanied balloon expulsion test. When results techniques...