Vicent Hernández
A5087537356- Inflammatory Bowel Disease
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Diverticular Disease and Complications
- Genetic factors in colorectal cancer
- Diagnosis and treatment of tuberculosis
- Bladder and Urothelial Cancer Treatments
- Autoimmune and Inflammatory Disorders
- Colorectal Cancer Surgical Treatments
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
- Pregnancy and Medication Impact
- Celiac Disease Research and Management
- Tuberculosis Research and Epidemiology
- Gastrointestinal disorders and treatments
- Pancreatitis Pathology and Treatment
- Immunodeficiency and Autoimmune Disorders
- Biosimilars and Bioanalytical Methods
- Pharmaceutical studies and practices
- Esophageal Cancer Research and Treatment
University Hospital Complex Of Vigo
2016-2025
Servicio Gallego de Salud
2015-2025
Galicia Sur Biomedical Foundation
2017-2025
Universitat de València
2003-2024
Complexo Hospitalario Universitario A Coruña
2012-2021
University of Atlántico
2021
Universidad Autónoma de Madrid
2019
Hospital Universitario de La Princesa
2019
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2013-2019
Sociedad Española de Patología Digestiva
2019
Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies for colorectal-cancer screening in the average-risk population.
Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. reasons for these changes remain unknown. aim this study was to investigate whether an East–West gradient the IBD Europe exists. Design A prospective, uniformly diagnosed, population based inception cohort patients 31 centres from 14 Western and eight European countries covering a total background approximately 10.1 million people created. One-third had previous experience with cohorts. Patients were...
The Epi-IBD cohort is a prospective population-based inception of unselected patients with inflammatory bowel disease from 29 European centres covering background population almost 10 million people. aim this study was to assess the 5-year outcome and course Crohn's (CD).Patients were followed up prospectively time diagnosis, including collection their clinical data, demographics, activity, medical therapy, surgery, cancers deaths. Associations between outcomes multiple covariates analysed...
Objectives: to assess the salivary flow rate, pH, and buffer capacity of healthy volunteers, their relationships with age, gender, obesity, smoking, alcohol consumption, establish lower-end value normal (oligosialia).Methods: a prospective study was conducted in 159 volunteers (age > 18 years, absence medical conditions that could decrease flow).Unstimulated whole saliva collected during ten minutes, rate (ml/min), bicarbonate concentration (mmol/l) were measured using Radiometer ABL 520.The...
Few population-based cohort studies have assessed the disease course of ulcerative colitis [UC] in era biological therapy and widespread use immunomodulators. The aim this study was to assess 5-year outcome patients with UC Epi-IBD cohort.In a prospective, inception unselected UC, were followed up from time their diagnosis, which included collection clinical data, demographics, activity, medical therapy, rates surgery, cancers, deaths. Associations between outcomes multiple covariates...
Aliment Pharmacol Ther 2012; 35: 275–283 Summary Background Ciclosporin has proven to be effective in patients with corticosteroid‐refractory ulcerative colitis (UC). When therapy this drug fails, infliximab can considered avoid colectomy. The efficacy and safety of sequential approach remain unknown. Aim To assess the profile treatment after failure ciclosporin a flare UC. Methods Retrospective review medical records UC who did not respond received salvage within month discontinuing...
The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes environmental factors towards a more "westernised" standard living. aim this study was investigate differences exposure prior diagnosis and Western European IBD patients. EpiCom cohort population-based, prospective inception 1560 unselected patients from 31 countries covering background population 10.1 million. At the time were asked complete an 87-item questionnaire concerning factors....
The aim of the present study was to validate IBD (inflammatory bowel diseases) incidence reported in 2010 ECCO-EpiCom (European Crohn's and Colitis Organization-Epidemiological Committee) inception cohort by including a second independent from participating centers 2011 an Australian center investigate whether there is difference between Eastern Western European countries Australia.Fourteen 5 9 one Australia participated cohort. Patients' data regarding disease type, socio-demographic...
OBJECTIVES: Specific microRNA (miRNA) signatures in biological fluids can facilitate earlier detection of the tumors being then minimally invasive diagnostic biomarkers. Circulating miRNAs have also emerged as promising biomarkers for colorectal cancer (CRC) screening. In this study, we investigated performance a specific signature miRNA plasma samples to design robust predictive model that distinguish healthy individuals from those with CRC or advanced adenomas (AA) diseases. METHODS: Case...
The development programm UNIFI has shown promising results of ustekinumab in ulcerative colitis [UC] treatment which should be confirmed clinical practice. We aimed to evaluate the durability, effectiveness, and safety UC real life.Patients included prospectively maintained ENEIDA registry, who received at least one intravenous dose due active [Partial Mayo Score [PMS]>2], were included. Clinical activity effectiveness defined based on PMS. Short-term response was assessed Week 16.A total 95...
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe main epidemiological and clinical characteristics at diagnosis evolution disease, explore use drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 Spain were included followed-up for 1 year. (3) Results: We identified 3611 incident cases during 108 hospitals...
BackgroundThe EpiCom cohort is a prospective, population-based, inception of inflammatory bowel disease (IBD) patients from 31 European centers covering background population 10.1 million. The aim this study was to assess the 1-year outcome in cohort.
Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and externally validate a model, COLONPREDICT, clinical laboratory variables.This prospective cross-sectional study included consecutive gastrointestinal symptoms referred colonoscopy between March 2012 September 2013 derivation cohort 2014 2015 validation cohort. In cohort, we assessed...
Many diseases that affect modern humans fall in the category of complex diseases, thus called because they result from a combination multiple aetiological and pathogenic factors. Regardless organ or system affected, present major challenges diagnosis, classification, management. Current forms therapy are usually applied an indiscriminate fashion based on clinical information, but even most advanced drugs only benefit limited number patients to variable unpredictable degree. This 'one measure...
OBJECTIVES: To determine the prevalence of recurrence gallstone pancreatitis, its clinical features, and presence prognostic factors recurrence. METHODS: From January 1, 2000 to August 31, 2003, 233 patients admitted with acute pancreatitis (AGP) were prospectively studied. Patients divided into two groups: recurrent nonrecurrent group. Clinical, analytical, radiological, parameters, severity (Atlanta criteria) assessed, along performance cholecystectomy or endoscopic sphincterotomy (ES)....
To assess the fecal immunochemical test (FIT) accuracy for colorectal cancer (CRC) and advanced neoplasia (AN) detection in CRC screening.We performed a multicentric, prospective, double blind study of diagnostic tests on asymptomatic average-risk individuals submitted to screening colonoscopy. Two stool samples were collected hemoglobin concentration was determined first sample (FIT1) highest level both (FITmax) using OC-sensor™. Areas under curve (AUC) AN calculated. The best FIT1 FITmax...