Natalia García‐Morales
A5101464912- Inflammatory Bowel Disease
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Global Cancer Incidence and Screening
- Celiac Disease Research and Management
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Eosinophilic Disorders and Syndromes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Diagnosis and treatment of tuberculosis
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Dysphagia Assessment and Management
- Pancreatitis Pathology and Treatment
- Stoma care and complications
- Biosimilars and Bioanalytical Methods
- Colorectal Cancer Treatments and Studies
- Pharmaceutical studies and practices
University Hospital Complex Of Vigo
2020-2025
Servicio Gallego de Salud
2022-2025
Galicia Sur Biomedical Foundation
2022-2025
Complexo Hospitalario Universitario A Coruña
2020-2024
Universidade de Santiago de Compostela
2021-2023
Vanderbilt University
2022
Hospital Universitari i Politècnic La Fe
2016-2020
INTRODUCTION: Antibiotic resistance is one of the main factors that determine efficacy treatments to eradicate Helicobacter pylori infection. Our aim was evaluate effectiveness first-line and rescue against H. in Europe according antibiotics resistance. METHODS: Prospective, multicenter, international registry on management (European Registry Management). All infected culture-diagnosed adult patients registered Spanish Association Gastroenterology-Research Electronic Data Capture from 2013...
The role of computer-aided detection in identifying advanced colorectal neoplasia is unknown.To evaluate the contribution to colonoscopic neoplasias as well adenomas, serrated polyps, and nonpolypoid right-sided lesions.Multicenter, parallel, randomized controlled trial. (ClinicalTrials.gov: NCT04673136).Spanish cancer screening program.3213 persons with a positive fecal immunochemical test.Enrollees were randomly assigned colonoscopy or without detection.Advanced was defined adenoma and/or...
Abstract Background Poor adherence to clinical practice guidelines for eosinophilic esophagitis (EoE) has been described and the diagnostic delay of disease continues be unacceptable in many settings. Objective To analyze impact improved knowledge provided by successive international on reducing improving process European patients with EoE. Methods Cross‐sectional analysis EoE CONNECT registry based practice. Time periods defined publication dates four major sets over 10 years were...
The growing prevalence of eosinophilic esophagitis (EoE) represents a considerable burden to patients and health care systems. Optimizing cost-effective management identifying mechanisms for disease onset progression are required. However, the paucity large patient cohorts heterogeneity practice hinder defining optimal EoE.EoE CONNECT is an ongoing, prospective registry study initiated in 2016 currently managed by EUREOS, European Consortium Eosinophilic Diseases Gastrointestinal Tract....
Abstract This study compared short-term effectiveness of proton pump inhibitors (PPI), swallowed topical corticosteroids (STC), and dietary therapies in reversing clinical histological features pediatric patients with eosinophilic esophagitits (EoE). Determinants for treatment choice PPI therapy were also assessed. A cross-sectional analysis under 18 years old recruited onto the multicenter EoE CONNECT registry was performed. Clinico-histological response defined as symptomatic improvement...
Abstract Background Real-world data on the speed of onset ustekinumab (UST) in patients with ulcerative colitis (UC) are limited. Current information regarding early response these comes from UNIFI trial. The primary outcome this study was to evaluate UST moderate-to-severe UC by assessing PRO2 at 14 days after first intravenous dose (6mg/kg). Methods A multicenter, prospective observational designed ≥18 years old (partial Mayo score ≥6) who initiated 6mg/kg between June 2023 and September...
Abstract Background Anti-tumor necrosis factor (anti-TNF) drugs usually represent the first line of biological therapy in inflammatory bowel disease (IBD) patients. The presence HLA-DQA1*05 allele has been linked to a higher risk immunogenicity and development anti-drug antibodies. This condition may increase likelihood primary treatment failure or loss response anti-TNF medications. However, clinical data on this topic are scarce often contradictory. Methods Prospective, single-center...
ABSTRACT Background The EXIT trial found no difference in sustained remission at 12 months between inflammatory bowel disease (IBD) patients who withdrew anti‐TNF therapy [withdrawal arm (WA)] and those maintained treatment [maintenance (MA)]. Aims To compare the long‐term risk of relapse these groups assess response to resumption. Methods This was a follow‐up extension trial. We analysed outcomes clinical from start EXIT. Results included 125 (63 MA 62 WA). Median for 26 WA. cumulative...
Background: The usefulness of thiopurines has been poorly explored in pouchitis and other pouch disorders. Objective: To evaluate the effectiveness safety azathioprine as maintenance therapy inflammatory Design: This was a retrospective multicentre study. Methods: We included patients diagnosed with disorders treated monotherapy. Effectiveness evaluated at 1 year long term based on normalization stool frequency, absence pain, faecal urgency or fistula discharge (clinical remission), any...
Several methods are available to diagnose Helicobacter pylori infection. Our objective was evaluate the tests used for both initial diagnosis and confirmation of eradication after treatment in Europe.The European Registry on management infection is an international, multicentre, prospective, non-interventional registry aiming pylori-infected patients Europe. Countries with at least 100 cases registered from June 2013 April 2021, a validated diagnostic method were analysed. Data quality...
Abstract Golimumab has demonstrated its long-term efficacy and safety in ulcerative colitis clinical trials, but no data of persistence been published from real world. To estimate golimumab, as well factors associated with longer persistence, patients life. Observational multicentre study including adult treated golimumab at least twelve months follow-up. We included 190 patients, 105 (55.26%) naive to anti-TNF, mean disease duration 9.32 ± 8.09 years. Probability was 63%, 46%, 39% 27% 1, 2,...
Background The ideal treatment approach for H. pylori infection has not yet been defined; therefore, the most effective management strategies adult patients need to be identified ensure clinical practice is aligned with best standard of care. Our aim was perform a review research studies from European Registry on (Hp-EuReg) by synthesizing clinically relevant information each published manuscript. Methods All between 2013 and 2022, evaluating any related within Hp-EuReg, long-term registry...
Introduction Patient blood management (PBM) adherence in clinical practice is unclear. This real-world study assessed the of patients with gastrointestinal (GI) bleeding after implementation PBM strategy. Methods was a nationwide multicenter and prospective involving consecutive adults GI between March 2019 2021. Patients were examined according to hemoglobin (Hb) level at admission (<7 g/dl, n = 93; 7–8 47; 8–9 61; >9 249). Study outcomes measures morbidity mortality during...
Eosinophilic esophagitis (EoE) predominantly affects males across all ages; however, little is known about sex differences for other aspects of EoE.
Annual albuminuria screening detects the early stages of nephropathy in individuals with diabetes. Because detection allows for interventions that lower risk developing chronic kidney disease, guidelines recommend annual testing all type 2 diabetes mellitus and those 1 at least 5 years. However, Eskind Diabetes Clinic Vanderbilt University Medical Center, occurred less frequently than desired.A quality improvement team first analysed clinic's processes, identifying lack a systematic approach...