A5087339988- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Gastroesophageal reflux and treatments
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Image Retrieval and Classification Techniques
- Metastasis and carcinoma case studies
- Medical Device Sterilization and Disinfection
- Eosinophilic Esophagitis
- AI in cancer detection
- Pancreatitis Pathology and Treatment
- Dysphagia Assessment and Management
- Neuroendocrine Tumor Research Advances
- Head and Neck Cancer Studies
- Colorectal and Anal Carcinomas
- Gastrointestinal Bleeding Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Diverticular Disease and Complications
Instituto Português de Oncologia de Coimbra Francisco Gentil
2008-2025
Instituto Português de Oncologia Francisco Gentil
2016-2025
Universidade do Porto
2016-2025
IPO Porto
2025
Centre for Health Technology and Services Research
2011-2021
RELX Group (Netherlands)
2020
Technologies pour la Santé
2014
Sociedade Portuguesa de Cardiologia
2014
University of Coimbra
2006-2010
Hy-Line (United States)
2008
Main Recommendations Patients with chronic atrophic gastritis or intestinal metaplasia (IM) are at risk for gastric adenocarcinoma. This underscores the importance of diagnosis and stratification these patients. High definition endoscopy chromoendoscopy (CE) is better than high white-light alone this purpose. Virtual CE can guide biopsies staging metaplastic changes target neoplastic lesions. Biopsies should be taken from least two topographic sites (antrum corpus) labelled in separate...
Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common associated with an increased risk for gastric cancer. In absence guidelines, there is wide disparity in management patients these premalignant conditions. The European Society Gastrointestinal Endoscopy (ESGE), Helicobacter Study Group (EHSG), Pathology (ESP) Sociedade Portuguesa de Endoscopia Digestiva (SPED) have therefore combined efforts to develop evidence-based guidelines on precancerous...
Artificial intelligence (AI) tools increase detection of precancerous polyps during colonoscopy and might contribute to long-term colorectal cancer prevention. The aim the study was investigate incremental effect implementation AI in screening on incidence mortality, cost-effectiveness such tools.We conducted Markov model microsimulation using with without for individuals at average risk (no personal or family history cancer, adenomas, inflammatory bowel disease, hereditary syndrome). We ran...
Abstract This ESGE Position Statement defines the expected value of artificial intelligence (AI) for diagnosis and management gastrointestinal neoplasia within framework performance measures already defined by ESGE. is based on clinical relevance task preliminary evidence regarding in or settings. Main recommendations: (1) For acceptance AI assessment completeness upper GI endoscopy, adequate level mucosal inspection with should be comparable to that assessed experienced endoscopists. (2)...
<b>Background and study aim: </b>The reliability external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim current was to describe estimate accuracy a simplified classification system for NBI diagnosis gastric lesions. <b>Methods: </b>Consecutive patients undergoing endoscopy at two reference centers (n = 85, 33 % with dysplasia) were included studies. In total, 224 different areas biopsied recorded onto video. derivation study, previously...
Summary of statements In Europe at present, but also in 2040, 1 3 cancer-related deaths are expected to be caused by digestive cancers. Endoscopic technologies enable diagnosis, with relatively low invasiveness, precancerous conditions and early cancers, thereby improving patient survival. Overall, endoscopy capacity must adjusted facilitate both effective screening programs rigorous control the quality assurance surveillance systems required. For average-risk populations, ESGE recommends...
Endoscopic screening for gastric cancer is debatable in countries with an intermediate risk.The objective of this article to determine the cost-utility strategies a European country.We conducted analysis using Markov model comparing three versus no screening: stand-alone upper endoscopy, endoscopy combined colorectal colonoscopy after positive faecal occult blood test or pepsinogens serologic screening. Clinical data were collected from systematic reviews, costs published national and...
INTRODUCTION: The safety of Helicobacter pylori eradication treatments and to what extent adverse events (AEs) influence therapeutic compliance in clinical practice are hardly known. Our aim was assess the frequency, type, intensity, duration AEs, their impact on compliance, for most frequently used “European Registry management.” METHODS: Systematic prospective noninterventional registry European gastroenterologists (27 countries, 300 investigators) management H. infection routine practice....
There has been resurgence in the use of bismuth quadruple therapy (proton pump inhibitor, bismuth, tetracycline and metronidazole) for treating Helicobacter pylori infection thanks to a three-in-one single-capsule formulation.To evaluate effectiveness safety therapy.Data were collected multicentre, prospective registry clinical practice gastroenterologists on management H. infection, where patients registered at Asociación Española de Gastroenterologia REDCap database an electronic case...
Background Progression of extensive gastric premalignant conditions to cancer might warrant surveillance programms. Recent guidelines suggest a 3‐yearly endoscopic follow‐up for these patients. Our aim was determine the cost utility patients with such as atrophy or intestinal metaplasia. Materials and Methods A cost‐utility economic analysis performed from societal perspective in Portugal using Markov model compare two strategies: versus no surveillance. Clinical data were collected...
<b>Background and study aim</b> Upper endoscopy is the most common method for diagnosis of upper gastrointestinal tract diseases. The aim this was to determine whether premedication with simethicone or <i>N</i>-acetylcysteine improves mucosal visualization during endoscopy. <b>Patients methods</b> This a randomized, double-blind, placebo-controlled 297 patients scheduled who were premedicated 15 – 30 minutes before procedure with: 100 mL water (placebo, group A); plus mg (group B); 600 C)....
Main Recommendations At a population level, the European Society of Gastrointestinal Endoscopy (ESGE), Helicobacter and Microbiota Study Group (EHMSG), Pathology (ESP) suggest endoscopic screening for gastric cancer (and precancerous conditions) in high-risk regions (age-standardized rate [ASR] > 20 per 100 000 person-years) every 2 to 3 years or, if cost–effectiveness has been proven, intermediate risk (ASR 10–20 5 years, but not low-risk < 10). ESGE/EHMSG/ESP recommend that...