Raf Bisschops

ORCID: 0000-0002-9994-8226
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About
Contact & Profiles
Research Areas
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Screening and Detection
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • Inflammatory Bowel Disease
  • Gastroesophageal reflux and treatments
  • Helicobacter pylori-related gastroenterology studies
  • Eosinophilic Esophagitis
  • Microscopic Colitis
  • Gastrointestinal motility and disorders
  • Radiomics and Machine Learning in Medical Imaging
  • Colorectal Cancer Surgical Treatments
  • Gastrointestinal Tumor Research and Treatment
  • Dysphagia Assessment and Management
  • Lung Cancer Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Tracheal and airway disorders
  • Mycobacterium research and diagnosis
  • Pancreatic and Hepatic Oncology Research
  • Metastasis and carcinoma case studies
  • Diverticular Disease and Complications
  • Genetic factors in colorectal cancer
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Medical Device Sterilization and Disinfection
  • Bariatric Surgery and Outcomes

KU Leuven
2016-2025

Universitair Ziekenhuis Leuven
2015-2025

RELX Group (Netherlands)
2018-2022

Albert Schweitzer Ziekenhuis
2014-2021

University Gastroenterology
2021

Antwerp University Hospital
2020

Metropolitan University
2019

Norgine (United Kingdom)
2018

Astellas Pharma (United States)
2015

Olympus (United States)
2015

The European Society of Gastrointestinal Endoscopy and United Gastroenterology present a short list key performance measures for lower gastrointestinal endoscopy. We recommend that endoscopy services across Europe adopt the following seven measurement evaluation in daily practice at center endoscopist level: <b>1</b> Rate adequate bowel preparation (minimum standard 90 %); <b>2</b> Cecal intubation rate <b>3</b> Adenoma detection 25 <b>4 </b>Appropriate polypectomy technique 80 <b>5</b>...

10.1055/s-0043-103411 article EN Endoscopy 2017-03-07

<h3>Importance</h3> Barrett esophagus containing low-grade dysplasia is associated with an increased risk of developing esophageal adenocarcinoma, a cancer rapidly increasing incidence in the western world. <h3>Objective</h3> To investigate whether endoscopic radiofrequency ablation could decrease rate neoplastic progression. <h3>Design, Setting, and Participants</h3> Multicenter randomized clinical trial that enrolled 136 patients confirmed diagnosis at 9 European sites between June 2007...

10.1001/jama.2014.2511 article EN JAMA 2014-03-25

Current practices for the management of Barrett's esophagus (BE) vary across Europe, as several national European guidelines exist. This Position Statement from Society Gastrointestinal Endoscopy (ESGE) is an attempt to homogenize recommendations and, hence, patient according best scientific evidence and other considerations (e.g. health policy). A Working Group developed consensus statements, using existing a starting point considering new in literature. The wishes contribute more...

10.1055/s-0042-122140 article EN Endoscopy 2017-01-25

ESGE recommends a low fiber diet on the day preceding colonoscopy.Strong recommendation, moderate quality evidence.ESGE use of enhanced instructions for bowel preparation.Strong suggests adding oral simethicone to preparation.Weak split-dose preparation elective high recommends, patients undergoing afternoon colonoscopy, same-day as an acceptable alternative split dosing.Strong start last dose within 5 hours and complete it at least 2 before beginning procedure.Strong volume or PEG-based...

10.1055/a-0959-0505 article EN Endoscopy 2019-07-11

ESGE recommends that the evaluation of superficial gastrointestinal (GI) lesions should be made by an experienced endoscopist, using high definition white-light and chromoendoscopy (virtual or dye-based).ESGE does not recommend routine performance endoscopic ultrasonography (EUS), computed tomography (CT), magnetic resonance imaging (MRI), positron emission (PET)-CT prior to resection.ESGE submucosal dissection (ESD) as treatment choice for most esophageal squamous cell gastric lesions.For...

10.1055/a-1811-7025 article EN Endoscopy 2022-05-06

This Guideline is an official statement of the European Society Gastrointestinal Endoscopy (ESGE). It addresses role advanced endoscopic imaging for detection and differentiation colorectal neoplasia. <b>Main recommendations</b> <b>1</b> ESGE suggests routine use high definition white-light endoscopy systems detecting neoplasia in average risk populations (weak recommendation, moderate quality evidence). <b>2</b> recommends pancolonic conventional or virtual (narrow band [NBI], i-SCAN)...

10.1055/s-0034-1365348 article EN Endoscopy 2014-03-17

Abstract We are currently living in the throes of COVID-19 pandemic that imposes a significant stress on health care providers and facilities. Europe is severely affected with an exponential increase incident infections deaths. The clinical manifestations can be subtle, encompassing broad spectrum from asymptomatic mild disease to severe respiratory illness. Health professionals endoscopy units at increased risk infection COVID-19. Infection prevention control has been shown dramatically...

10.1055/a-1155-6229 article EN other-oa Endoscopy 2020-04-17

Summary Background Uncontrolled studies suggest benefit of intrapyloric injection botulinum toxin (botox) for the treatment gastroparesis, but controlled data are lacking. Aim To perform a study botox in gastroparesis. Methods Twenty‐three gastroparesis patients (five men, age 45 ± 3, 19 idiopathic) underwent two upper endoscopies with 4‐week interval, saline or 4 × 25 U randomized double‐blind‐controlled crossover fashion. Before start and weeks after each treatment, they solid liquid...

10.1111/j.1365-2036.2007.03467.x article EN Alimentary Pharmacology & Therapeutics 2007-08-22

In many medical imaging and classical computer vision tasks, the Dice score Jaccard index are used to evaluate segmentation performance. Despite existence great empirical success of metric-sensitive losses, i.e. relaxations these metrics such as soft Dice, Lovasz-Softmax, researchers still use per-pixel (weighted) cross-entropy train CNNs for segmentation. Therefore, target metric is in cases not directly optimized. We investigate from a theoretical perspective, relation within group loss...

10.1109/tmi.2020.3002417 article EN IEEE Transactions on Medical Imaging 2020-06-15

OBJECTIVES: Endoscopic mucosal healing is a key endpoint for the treatment of ulcerative colitis (UC). The role microscopic activity in predicting disease relapse has not been fully assessed. We aimed to investigate predictive serologic and histologic markers on UC patients with endoscopically inactive disease. METHODS: Adult (Mayo 0) 12-month follow-up between 2008 2011 were retrospectively included. An expert pathologist evaluated all colonic biopsies (Geboes score) presence basal...

10.1038/ajg.2012.301 article EN The American Journal of Gastroenterology 2012-11-01

Main Recommendations 1 ESGE suggests that high definition endoscopy, and dye or virtual chromoendoscopy, as well add-on devices, can be used in average risk patients to increase the endoscopist’s adenoma detection rate. However, their routine use must balanced against costs practical considerations. Weak recommendation, quality evidence. 2 recommends of systems individuals with Lynch syndrome. Strong 3 use, targeted biopsies, dye-based pancolonic chromoendoscopy for neoplasia surveillance...

10.1055/a-1031-7657 article EN Endoscopy 2019-11-11

Focal endoscopic resection (ER) followed by radiofrequency ablation (RFA) safely and effectively eradicates Barrett's oesophagus (BO) containing high-grade dysplasia (HGD) and/or early cancer (EC) in smaller studies with limited follow-up. Herein, we report long-term outcomes of combined ER RFA for BO (HGD EC) from a single-arm multicentre interventional study.In 13 European centres, patients ≤ 12 cm HGD EC on 2 separate endoscopies were eligible inclusion. Visible lesions (<2 length; <50%...

10.1136/gutjnl-2015-309298 article EN Gut 2015-03-02

The duodenum has become a metabolic treatment target through bariatric surgery learnings and the specific observation that bypassing, excluding or altering duodenal nutrient exposure elicits favourable changes. Duodenal mucosal resurfacing (DMR) is novel endoscopic procedure been shown to improve glycaemic control in people with type 2 diabetes mellitus (T2D) irrespective of body mass index (BMI) DMR involves catheter-based circumferential lifting followed by hydrothermal ablation mucosa....

10.1136/gutjnl-2019-318349 article EN cc-by-nc Gut 2019-07-22

<b>Background and study aims:</b> Early neoplasia in Barrett's esophagus is difficult to detect often overlooked during surveillance. An automatic detection system could be beneficial, by assisting endoscopists with of early neoplastic lesions. The aim this was assess the feasibility a computer esophagus. <b>Patients methods:</b> Based on 100 images from 44 patients esophagus, algorithm, which employed specific texture, color filters, machine learning, developed for lesions evaluation one...

10.1055/s-0042-105284 article EN Endoscopy 2016-04-21

Abstract Climate change and the destruction of ecosystems by human activities are among greatest challenges 21st century require urgent action. Health care significantly contribute to emission greenhouse gases waste production, with gastrointestinal (GI) endoscopy being one largest contributors. This Position Statement aims raise awareness ecological footprint GI provides guidance reduce its environmental impact. The European Society Gastrointestinal Endoscopy (ESGE) Gastroenterology Nurses...

10.1055/a-1859-3726 article EN Endoscopy 2022-07-08

Background In the first (prevalent) supplemental MRI screening round of Dense Tissue and Early Breast Neoplasm Screening (DENSE) trial, a considerable number breast cancers were found at cost an increased false-positive rate (FPR). incident rounds, lower cancer detection (CDR) is expected due to smaller pool prevalent cancers, reduced FPR, availability prior examinations. Purpose To investigate performance indicators second (incidence round) DENSE trial. Materials Methods The trial...

10.1148/radiol.2021203633 article EN Radiology 2021-03-16
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