A5029869775- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Gallbladder and Bile Duct Disorders
- Biliary and Gastrointestinal Fistulas
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Health and Medical Education
- Pancreatitis Pathology and Treatment
- Diverticular Disease and Complications
- Liver Disease and Transplantation
- Esophageal Cancer Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Public Health and Environmental Issues
- Stoma care and complications
- Gastroesophageal reflux and treatments
- Medical Device Sterilization and Disinfection
Instituto de investigación sanitaria y biomédica de Alicante
2017-2025
Hospital General Universitario de Alicante Doctor Balmis
2017-2025
Universitat de Miguel Hernández d'Elx
2022-2025
Hospital General Universitario de Elche
2018
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2017
ESGE recommends a low fiber diet on the day preceding colonoscopy.Strong recommendation, moderate quality evidence.ESGE use of enhanced instructions for bowel preparation.Strong suggests adding oral simethicone to preparation.Weak split-dose preparation elective high recommends, patients undergoing afternoon colonoscopy, same-day as an acceptable alternative split dosing.Strong start last dose within 5 hours and complete it at least 2 before beginning procedure.Strong volume or PEG-based...
The role of computer-aided detection in identifying advanced colorectal neoplasia is unknown.To evaluate the contribution to colonoscopic neoplasias as well adenomas, serrated polyps, and nonpolypoid right-sided lesions.Multicenter, parallel, randomized controlled trial. (ClinicalTrials.gov: NCT04673136).Spanish cancer screening program.3213 persons with a positive fecal immunochemical test.Enrollees were randomly assigned colonoscopy or without detection.Advanced was defined adenoma and/or...
Evidence on adherence, diagnostic performance and impact survival to intensive follow-up after surgery for colorectal cancer (CRC) is limited. To analyze the of surveillance colonoscopy, computed tomography (CT), tumor markers (TMs) in detecting CRC recurrence or metastasis during resection. Secondary objectives included degree adherence clinical practice guidelines recommendations factors associated with all-cause mortality. The single-center retrospective cohort study including patients...
Abstract Background Post‐colonoscopy colorectal cancer (PCCRC) is (CRC) diagnosed after a colonoscopy in which no found. Objective As PCCRC has become an important quality indicator, we determined its rates, characteristics, and index colonoscopy‐related predictive factors. Methods We carried out multicenter, observational, retrospective study between 2015 2018. Rates were calculated for developing up to 10 years colonoscopy. was categorized according the most plausible explanation using...
Backgrounds and Aims: Cold snare EMR (CS-EMR) in large flat non-pedunculated colonic lesions (LFNPCLs) is an alternative to the standard procedure with a better safety profile, but scientific evidence on its efficacy unavailable. Primary objective: To compare recurrence rate between two techniques at six months. Secondary objectives: comparison of profile several procedure-related outcomes. Patients methods: This was noninferiority, multicentric, open-label, randomized controlled trial...
Objective The aim of this study was to validate a molecular classification colorectal cancer (CRC) based on microsatellite instability (MSI), CpG island methylator phenotype (CIMP) status, BRAF, and KRAS investigate each subtype's response chemotherapy. Design This retrospective observational included population-based cohort 878 CRC patients. We classified tumours into five different subtypes BRAF mutation, CIMP MSI. Patients with advanced stage II (T4N0M0) III received 5-fluoruracil...
High-risk features of colonic polyps are based on size, number, and pathologic characteristics. Surveillance colonoscopy is often recommended according to these findings. This study aimed determine whether the molecular characteristics might provide information about risk metachronous advanced neoplasia.We retrospectively included 308 patients with polyps. A total 995 were collected tested for somatic BRAF KRAS mutations. Patients classified into 3 subgroups, polyp mutational profile at...
Background: Delayed post-polypectomy bleeding (DPPB) is the most common adverse event following colonic polypectomy, yet its management remains highly heterogeneous and lacks standardization. A considerable number of colonoscopies performed for DPPB may be unnecessary do not result in hemostatic intervention. Objectives: To develop evidence-based statements to guide clinical decision-making DPPB. Design: Multidisciplinary Delphi consensus statement. Methods: panel 29 experts...
Objectives: To compare metachronous colorectal cancer (CRC) and advanced adenoma (AA) risk in patients with proximal vs. distal adenomas. Methods: We searched Pubmed, EMBASE, Cochrane for cohort studies clinical trials. Proximal adenomas were those located to the descending colon. Pooled incidence rate ratios (IRR) CRC AA calculated using a random-effects model. Results: Compared only adenomas, any had higher of (1.70, 95%CI 1.17-2.45), (3.65,95%CI 1.57-8.46), (1.82,95%CI 1.41-2.34) ....
Background Guidelines recommend surveillance colonoscopies based exclusively on findings at baseline colonoscopy. This recommendation leads to the paradox that higher colonoscopy quality, more will be indicated according current guidelines. Objective The aim of this study was evaluate effect follow‐up different quality metrics endoscopist performing Methods retrospective cohort included individuals with advanced adenomas Adenoma detection rate (ADR) and per (APCR) were determined for 44...
Abstract Background Current guidelines regarding surveillance after screening colonoscopy assume adequate bowel preparation. However, follow-up intervals suboptimal cleansing are highly heterogeneous. We aimed to determine the diagnostic yield of early repeat in patients with preparation fecal immunochemical test (FIT)-based colonoscopy. Methods An observational study including who underwent positive FIT and then within 1 year. Suboptimal was defined as a Boston Bowel Preparation Scale...
Aims The OLGA system assesses both gastric atrophy (GA) and intestinal metaplasia (IM) together as a severity overall which must be estimated by pathologists. OLGIM is based on the IM recommended updated Sydney system. Thus, final score can any clinician. Currently, there no that addresses of GA they are reported following recommendation. This study aimed to assess utility new system, OLGIMA (Operative Link Gastric assessment), tool identify patients at higher risk for GC in daily practice.
Abstract Background The potential of molecular markers in the removed polys as reliable predictors metachronous lesions is still uncertain. Aim Our aim was to evaluate role somatic mutations KRAS polyps patients with high‐risk adenomas predict risk advanced or colorectal cancer (CRC) within 3 years. Methods A total 518 were prospectively enrolled. included had ≥10 mm, high‐grade dysplasia, villous component ≥3 more at baseline and scheduled undergo surveillance colonoscopy years ± 6 months....