A5049221351- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Pancreatitis Pathology and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Gastrointestinal disorders and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Biliary and Gastrointestinal Fistulas
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Tracheal and airway disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Colorectal Cancer Surgical Treatments
Elisabeth-Krankenhaus Essen
2015-2024
Essen University Hospital
2008-2023
University of Duisburg-Essen
2008-2022
Evangelisches Krankenhaus Düsseldorf
2009-2021
University Hospital Augsburg
2016
Heinrich Heine University Düsseldorf
1989-2013
State of The Art
2012
Optica
2012
Catalina Scientific (United States)
2012
University of Tübingen
2009
This Guideline is an official statement of the European Society Gastrointestinal Endoscopy (ESGE), endorsed by for Radiotherapy and Oncology (ESTRO), Digestive (ESDO), Clinical Nutrition Metabolism (ESPEN). The Grading Recommendations Assessment, Development, Evaluation (GRADE) system was adopted to define strength recommendations quality evidence. Main malignant disease 1 ESGE recommends placement partially or fully covered self-expandable metal stents (SEMSs) palliative treatment dysphagia...
Objective Endoscopic full-thickness resection (EFTR) is a novel treatment of colorectal lesions not amenable to conventional endoscopic resection. The aim this prospective multicentre study was assess the efficacy and safety device. Design 181 patients were recruited in 9 centres with indication difficult adenomas (non-lifting and/or at locations), early cancers subepithelial tumours (SET). Primary endpoint complete en bloc R0 Results EFTR technically successful 89.5%, rate 76.9%. In 127...
Focal endoscopic resection (ER) followed by radiofrequency ablation (RFA) safely and effectively eradicates Barrett's oesophagus (BO) containing high-grade dysplasia (HGD) and/or early cancer (EC) in smaller studies with limited follow-up. Herein, we report long-term outcomes of combined ER RFA for BO (HGD EC) from a single-arm multicentre interventional study.In 13 European centres, patients ≤ 12 cm HGD EC on 2 separate endoscopies were eligible inclusion. Visible lesions (<2 length; <50%...
<h3>Background</h3> For endoscopic resection of early GI neoplasia, submucosal dissection (ESD) achieves higher rates complete (R0) than mucosal (EMR). However, ESD is technically more difficult and evidence from randomised trial missing. <h3>Objective</h3> We compared the efficacy safety EMR in patients with neoplastic Barrett9s oesophagus (BO). <h3>Design</h3> BO a focal lesion high-grade intraepithelial neoplasia (HGIN) or adenocarcinoma (EAC) ≤3 cm were to either EMR. Primary outcome was...
Endoscopic mucosal resection (EMR) of early gastrointestinal cancers has been shown to be effective in treating malignancies, but en bloc (where the entire tumor is removed one piece) often not achieved using conventional cap EMR. Other techniques, developed Japan, include application different types knife such as insulated-tip instrument. We report our preliminary experience use this knife, conjunction with other attempting and adenomas removal submucosal tumors (SMTs) upper tract.A total...
OBJECTIVES: Endoscopic removal of large, nonpedunculated colorectal lesions is challenging. Long-term outcome data based on standardized protocols, including detailed inspection the resection site, are scarce. The aims present study were to evaluate safety and efficacy endoscopic (ER) (LNLs; >20 mm) assess long-term recurrence rate afterward. METHODS: A total 243 consecutive patients (141 men, 102 women) with 252 adenomas (>20 was followed up using a protocol after complete ER. After...
See also: Commentaire de travail M. Philipper et al., pp. 300Endoscopy 2010; 42(04): 349-349DOI: 10.1055/s-0031-1291847
Endoscopic submucosal dissection (ESD) enables the curative resection of early malignant lesions and is associated with reduced recurrence risk. Due to lack comprehensive ESD data in West, German registry was set up evaluate relevant outcomes ESD.The a prospective uncontrolled multicenter study. During 35-month period, 20 centers included 1000 ESDs neoplastic lesions. The results were evaluated terms en bloc, R0, rates, rate after 3-month 12-month follow-up. Additionally, participating...
Acute non-variceal upper gastrointestinal bleeding (NVUGIB) is managed by standard endoscopic combination therapy, but a few cases remain difficult and carry high risk of persistent or recurrent bleeding. The aim our study was to compare first-line over-the-scope-clips (OTSC) therapy with treatment in these selected patients.We conducted prospective, randomised, controlled, multicentre (NCT03331224). Patients evidence acute NVUGIB rebleeding (defined as complete Rockall Score ≥7) were...
<b>Background and study aims: </b>Endoscopic submucosal dissection (ESD) of early gastrointestinal tumors has been shown to achieve complete resection rates superior endoscopic mucosal (EMR), but at the cost higher risk. The aim this was prospectively assess feasibility oncological results ESD in patients with neoplastic Barrett’s esophagus conjunction subsequent radiofrequency ablation (RFA). <b>Methods: </b>Patients who had visible lesions containing high grade intraepithelial neoplasia...
Background and Study Aims: The correct localization of insulinomas using endoscopic ultrasonography (EUS) has been reported to be as high 80 % in multicenter patient cohorts.
See also: Commentaire de "Traitement endoscopique du diverticule Zenker: le choix des armes", pp. 141, 131, 137, 146Endoscopy 2007; 39(02): 193-193DOI: 10.1055/s-0032-1306914
Background and Study Aims: Unsedated esophagogastroduodenoscopy (EGD) has advantages over sedated EGD - e. g., prevention of side effects related to sedation, less patient monitoring, expense. This study compared the feasibility tolerance transnasal small-caliber (TSC-EGD) peroral (PSC-EGD) with conventional (C-EGD). Patients Methods: A total 150 patients referred for diagnostic were randomly allocated undergo either TSC-EGD, PSC-EGD, or C-EGD under local anesthesia if they agreed receive...
Background and study aims: Endoscopic submucosal dissection (ESD) is a promising therapeutic technique for en bloc resection of large gastrointestinal tumors. However, this has disadvantages such as long intervention time, complexity the procedure, higher rate complications. The primary aims were to show feasibility ESD in pig colon evaluate new comprising use newly developed hybrid knife procedures combining RF (radiofrequency) application distance-dependent water-jet application.
Abstract Background Personalized therapy planning remains a significant challenge in advanced colorectal cancer care, despite extensive research on prognostic and predictive markers. A strong correlation of sarcopenia or overall body composition survival has been described. Here, we explore whether automated assessment liver metastases from standard care CT images can add to clinical parameters personalized risk prognostication. Methods We retrospectively analysed imaging data 85 patients...