A5001524643- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Hepatitis Viruses Studies and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis C virus research
- Drug-Induced Hepatotoxicity and Protection
- Abdominal vascular conditions and treatments
- Eicosanoids and Hypertension Pharmacology
- Venous Thromboembolism Diagnosis and Management
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Nitric Oxide and Endothelin Effects
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Alcohol Consumption and Health Effects
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Biochemical effects in animals
- Liver physiology and pathology
- Liver Diseases and Immunity
- Blood Coagulation and Thrombosis Mechanisms
- Pulmonary Hypertension Research and Treatments
- Hepatitis B Virus Studies
- Gastroesophageal reflux and treatments
- Kruppel-like factors research
- Pregnancy and preeclampsia studies
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2025
Hospital Clínic de Barcelona
2016-2025
Universitat de Barcelona
2016-2025
Fundación Marques de Valdecilla
2025
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2016-2025
Instituto de Salud Carlos III
2011-2024
Centre for Biomedical Network Research on Rare Diseases
2019-2024
Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer
2024
Departament de Salut
2023-2024
Fundació Clínic per a la Recerca Biomèdica
2023-2024
Patients with cirrhosis in Child-Pugh class C or those B who have persistent bleeding at endoscopy are high risk for treatment failure and a poor prognosis, even if they undergone rescue transjugular intrahepatic portosystemic shunt (TIPS). This study evaluated the earlier use of TIPS such patients.We randomly assigned, within 24 hours after admission, total 63 patients acute variceal had been treated vasoactive drugs plus endoscopic therapy to polytetrafluoroethylene-covered stent 72...
Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.We randomly assigned 213 patients with cirrhosis hypertension (minimal hepatic venous gradient [HVPG] of 6 mm Hg) to receive timolol, a nonselective beta-blocker (108 patients), or placebo (105 patients). The primary end point was the development gastroesophageal Endoscopy HVPG measurements were repeated yearly.During median follow-up 54.9...
Current recommendations for early anticoagulation in acute portal vein thrombosis unrelated to cirrhosis or malignancy are based on limited evidence. The aim of this study was prospectively assess the risk factors, outcome, and prognosis patients managed according these recommendations. We enrolled 102 with vein, its left right branch. Laboratory investigations prothrombotic factors were centralized. Thrombus extension recanalization assessed by expert radiologists. A local factor identified...
Little information exists on the effects of transjugular intrahepatic portosystemic shunts (TIPS) in management cirrhotic patients with hepatorenal syndrome (HRS). The current study was aimed to prospectively evaluate TIPS renal function and vasoactive systems type I HRS. Glomerular filtration rate (GFR) (inulin clearance), plasma flow (RPF) (para-aminohippurate renin activity (PRA), aldosterone (ALDO), norepinephrine (NE), endothelin (ET) were determined baseline conditions at different...