A5018948457- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Lung Cancer Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Eosinophilic Esophagitis
- Metastasis and carcinoma case studies
- Dysphagia Assessment and Management
- Neuroendocrine Tumor Research Advances
- Medical Device Sterilization and Disinfection
- Colorectal Cancer Surgical Treatments
- Antifungal resistance and susceptibility
- Healthcare cost, quality, practices
- Inflammatory Bowel Disease
- Bariatric Surgery and Outcomes
Evangelisches Krankenhaus Düsseldorf
2016-2025
RELX Group (Netherlands)
2018-2023
Hochschule Düsseldorf University of Applied Sciences
2023
University Hospital Münster
2008-2019
University of Münster
2005-2017
Universitätsmedizin Greifswald
2014
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2007-2013
Main Recommendations Prophylaxis 1 ESGE recommends routine rectal administration of 100 mg diclofenac or indomethacin immediately before endoscopic retrograde cholangiopancreatography (ERCP) in all patients without contraindications to nonsteroidal anti-inflammatory drug administration. Strong recommendation, moderate quality evidence. 2 prophylactic pancreatic stenting selected at high risk for post-ERCP pancreatitis (inadvertent guidewire insertion/opacification the duct, double-guidewire...
<h3>Importance</h3> Case series suggest favorable results of peroral endoscopic myotomy (POEM) for treatment patients with achalasia. Data comparing POEM pneumatic dilation, the standard achalasia, are lacking. <h3>Objective</h3> To compare effects vs dilation as initial treatment-naive <h3>Design, Setting, and Participants</h3> This randomized multicenter clinical trial was conducted at 6 hospitals in Netherlands, Germany, Italy, Hong Kong, United States. Adult newly diagnosed achalasia an...
Objective Endoscopic full-thickness resection (EFTR) is a novel treatment of colorectal lesions not amenable to conventional endoscopic resection. The aim this prospective multicentre study was assess the efficacy and safety device. Design 181 patients were recruited in 9 centres with indication difficult adenomas (non-lifting and/or at locations), early cancers subepithelial tumours (SET). Primary endpoint complete en bloc R0 Results EFTR technically successful 89.5%, rate 76.9%. In 127...
Main Recommendations 1 ESGE recommends against diagnostic/therapeutic papillectomy when adenoma is not proven. Strong recommendation, low quality evidence. 2 endoscopic ultrasound and abdominal magnetic resonance cholangiopancreatography (MRCP) for staging of ampullary tumors. 3 in patients with without intraductal extension, because good results regarding outcome (technical clinical success, morbidity, recurrence).Strong moderate 4 en bloc resection adenomas up to 20–30 mm diameter achieve...
Main recommendations ESGE recommends considering the following indications for enteral tube insertion: (i) clinical conditions that make oral intake impossible (neurological conditions, obstructive causes); (ii) acute and/or chronic diseases result in a catabolic state where becomes insufficient; and (iii) small-bowel obstruction requiring decompression gastrostomy. Strong recommendation, low quality evidence. use of temporary feeding tubes placed through natural orifice (either nostril)...
Main recommendations ESGE recommends the “pull” technique as standard method for percutaneous endoscopic gastrostomy (PEG) placement. Strong recommendation, low quality evidence. direct introducer (“push”) PEG placement in cases where is contraindicated, example severe esophageal stenosis or patients with head and neck cancer (HNC) cancer. intravenous administration of a prophylactic single dose beta-lactam antibiotic (or appropriate alternative antibiotic, case allergy) to decrease risk...
Main recommendations 1 ESGE recommends that all duodenal adenomas should be considered for endoscopic resection as progression to invasive carcinoma is highly likely.Strong recommendation, low quality evidence. 2 performance of a colonoscopy, if has not yet been done, in cases adenoma. Strong 3 the use cap-assisted method when location minor and/or major papilla and their relationship adenoma clearly established during forward-viewing endoscopy. moderate 4 routine side-viewing endoscope...
Objective Currently available methods for small bowel endoscopy are often time consuming; motorised PowerSpiral Enteroscopy (PSE) is a further development of spiral enteroscopy to facilitate the approach bowel. The aim this bicentric prospective trial was study feasibility and yield peroral PSE. Design Consecutive patients with suspected disease indication antegrade were included in two tertiary referral centres. Primary objective diagnostic Secondary objectives technical success (defined as...
Abstract Background Motorized spiral enteroscopy (MSE) has been shown to be safe and effective for deep in studies performed at expert centers with limited numbers of patients without previous abdominal surgery. This study aimed investigate the safety, efficacy, learning curve associated MSE a real-life scenario, inclusion after surgery altered anatomy. Methods Patients indications were enrolled prospective observational multicenter study. The primary objective was serious adverse event...
Abstract Introduction Endoscopic detection of early neoplasia in Barrett's esophagus is difficult. Computer Aided Detection (CADe) systems may assist detection. The aim this study was to report the first steps development a CADe system for and evaluate its performance when compared with endoscopists. Methods This developed by consortium, consisting Amsterdam University Medical Center, Eindhoven Technology, 15 international hospitals. After pretraining, trained validated using 1.713...
BackgroundComputer-aided detection (CADe) systems could assist endoscopists in detecting early neoplasia Barrett's oesophagus, which be difficult to detect endoscopic images. The aim of this study was develop, test, and benchmark a CADe system for oesophagus.MethodsThe first pretrained with ImageNet followed by domain-specific pretraining GastroNet. We trained the on dataset 14 046 images (2506 patients) confirmed oesophagus non-dysplastic from 15 centres. Neoplasia delineated experts all...
<b>Background and study aims:</b> The Endocuff is a new colonoscopy accessory that has been designed to improve both the adenoma detection rate endoscope tip control. <b>Patients methods:</b> A total of 50 Endocuff-assisted colonoscopies were analyzed retrospectively with regard safety, procedural success, complications. <b>Results:</b> cecal intubation was 98 %, mean time 6.0 minutes (95 % confidence interval 5.3 – 6.6 minutes). ileal 76 %. In 30 patients, caused small, superficial,...
Endoscopic vacuum therapy (EVT) has emerged as a promising treatment option for upper gastrointestinal wall defects, offering benefits such evacuation of secretions and removal wound debris by suction, reduction healing cavities to improve clinical outcomes. In contrast, covered stents have high rate migration lack functional drainage, while endoluminal EVT devices obstruct the GI tract. The VACStent is novel device that combines stent placement. Its design features fully Nitinol-stent...
Background and aims In this pilot study we evaluated performance of a recently developed computer-aided detection (CADe) system for Barrett's neoplasia during live endoscopic procedures. Methods 15 patients with without visible lesion were included in study. A CAD assisted workflow was employed that included: slow pullback video recording the entire segment CADe assistance, followed by level-based recordings every 2cm segment. Outcomes per patient level diagnostic accuracy workflow, where...
Characterization of visible abnormalities in patients with Barrett's esophagus (BE) can be challenging, especially for inexperienced endoscopists. This results suboptimal diagnostic accuracy and poor interobserver agreement. Computer-aided diagnosis (CADx) systems may assist We aimed to develop, validate, benchmark a CADx system BE neoplasia.