A5076353735- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Organ Transplantation Techniques and Outcomes
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis C virus research
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Liver Diseases and Immunity
- Hepatitis Viruses Studies and Epidemiology
- Dysphagia Assessment and Management
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Hepatitis B Virus Studies
- Cytomegalovirus and herpesvirus research
- Inflammatory Bowel Disease
- Ultrasound in Clinical Applications
- Drug Transport and Resistance Mechanisms
- MRI in cancer diagnosis
- Microscopic Colitis
- Genetic factors in colorectal cancer
Krankenhaus der Barmherzigen Brüder Trier
2021-2025
University Hospital Münster
2015-2024
Krankenhaus Barmherzige Brüder
2023
University of Münster
2008-2021
Klinik für Schlafmedizin
2018-2020
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2008-2014
HELIOS Albert-Schweitzer-Klinik Northeim
2012
As a non-invasive and readily available diagnostic tool, ultrasound is one of the most important imaging techniques in medicine. Ultrasound usually trained during residency preferable according to German Society Medicine (DEGUM) standards. Our curriculum calls for undergraduate training medical students their 4th year education. An explorative pilot study evaluated acceptance this teaching method, compared it other practical activities education at Muenster University.240 participated...
AIM:To compare endoscopic retrograde cholangio-pancreatography (ERCP), intraductal ultrasound (IDUS), endosonography (EUS), transpapillary forceps biopsies (ETP) and computed tomography (CT) with respect to diagnosing malignant bile duct strictures. METHODS:A patient cohort strictures of unknown etiology was examined by ERCP IDUS, ETP, EUS, CT.The sensitivity, specificity, accuracy rates the diagnostic procedures were calculated based on definite diagnoses proved histopathology or long-term...
<b>Background and study aims:</b> The Endocuff is a new colonoscopy accessory that has been designed to improve both the adenoma detection rate endoscope tip control. <b>Patients methods:</b> A total of 50 Endocuff-assisted colonoscopies were analyzed retrospectively with regard safety, procedural success, complications. <b>Results:</b> cecal intubation was 98 %, mean time 6.0 minutes (95 % confidence interval 5.3 – 6.6 minutes). ileal 76 %. In 30 patients, caused small, superficial,...
Abstract The life expectancy of unresectable hilar cholangiocellular carcinomas (CCCs) is very limited and endoscopic radiofrequency ablation (ERFA) the biliary tract may prolong survival. Our single-center-study retrospectively analysed all CCC cases, in whom ERFAs were performed between 2012 2017 compared these to historical control cases who received standard treatment sole stent application. ERFA was 32 patients with malignant strictures that mainly caused by Bismuth III IV CCCs (66%)....
To evaluate medical versus interventional treatment (transjugular thrombus fragmentation, local thrombolysis with or without stent implantation) in patients acute non-cirrhotic, non-malignant portal vein thrombosis (PVT).This prospective, observational study enrolled 65 (<28 days since begin of symptoms, no cavernoma) PVT nine centres. Thirty received and 35 treatment. was graded into grade 1: short incomplete occlusion the vessel lumen 2: extended complete occlusion. Treatment response...
To determine the clinical outcome and predictors of survival after transjugular intrahepatic portosystemic stent shunt (TIPS) implantation in cirrhotic patients.Eighty-one patients with liver cirrhosis consequential portal hypertension had TIPS (bare metal) for either refractory ascites (RA) (n = 27) or variceal bleeding (VB) 54). Endpoints study were: technical success, occlusion stenosis, rebleeding, RA mortality. Clinical records were collected analysed. Baseline characteristics [e.g.,...
See also: Commentaire de travail T. Meister et al., pp. 331Endoscopy 2011; 43(04): 463-463DOI: 10.1055/s-0031-1291797
To evaluate predictive parameters for the development of Hepatic Encephalopathy (HE) after Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement and success shunt modification in management shunt-induced HE.A retrospective analysis all patients with TIPS (n = 344) has been performed since 2011 our university liver center. n 45 HE were compared to 48 without (case-control-matching). Of TIPS-induced HE, 20 received a reduction stent 18) or occlusion 2) differentiated into responders...
Transjugular intrahepatic portosystemic shunt (TIPS) implantation is an established procedure to treat portal hypertension with hepatic encephalopathy (HE) as a common complication. There lack of evidence concerning HE prophylaxis after TIPS.N = 233 patients receiving TIPS between 2011 and 2018 at German tertiary care center were included. Of them, 21% (n 49) had history HE. The follow-up period was 12 months. risk factors post-TIPS analyzed via multivariate analysis. efficacy prophylactic...
Imaging-based assessment of sarcopenia is a well-validated prognostic tool for patients with chronic liver disease. However, little known about its value in primary sclerosing cholangitis (PSC). This cross-sectional study aimed to investigate the predictive imaging-based skeletal muscle index (SMI) transplant-free survival (TFS) PSC.
Pneumocystis jirovecii pneumonia also known as pneumocystis (PCP) is an opportunistic respiratory infection in human immunodeficiency virus (HIV) patients that may develop non-HIV immunocompromised persons. The aim of our study was to evaluate mortality predictors PCP a tertiary referral centre.Fifty-one with symptomatic were enrolled the study. had either HIV (n = 21) or other immunosuppressive conditions 30). Baseline characteristics (e.g. age, sex and underlying disease) retrieved....
Aminopeptidase N (CD13) is present on tumor vasculature cells and some cells. Truncated tissue factor (tTF) with a C-terminal NGR-peptide (tTF-NGR) binds to CD13 causes vascular thrombosis infarction. We treated 17 patients advanced cancer beyond standard therapies in phase I study tTF-NGR (1-h infusion, central venous access, 5 consecutive days, rest periods of 2 weeks). The allowed intraindividual dose escalations between cycles established Maximum Tolerated Dose (MTD) Dose-Limiting...
The performance of endoscopic retrograde cholangiopancreaticography (ERCP) in patients with post-surgically altered anatomy is technically ambitious. Our study aimed at comparing a cohort having successfully undergone single-balloon enteroscopy (SBE)-assisted ERCP to those whom SBE-ERCP failed.This trial prospective single center study. Participants included 30 (median age 69.5 years, range 20-86 years) previous pancreaticobiliary surgery. First, conventional approach was attempted all...
AIMTo evaluate cholangioscopy in addition to endoscopic retrograde cholangiopancreatography (ERCP) for management of biliary complications after liver transplantation (LT). METHODSTwenty-six LT recipients with duct-to-duct reconstruction who underwent ERCP suspected between April and December
Transjugular intrahepatic portosystemic shunt (TIPS) implantation is an established procedure to treat portal hypertension. Impact of administration aspirin on transplant-free survival after TIPS remains unknown. A multicenter retrospective analysis including patients with between 2011 and 2018 at three tertiary German Liver Centers was performed. N = 583 were included. Survival performed in a matched cohort propensity score matching. Patients grouped according whether (PSM-aspirin-cohort)...