A5061011723- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Climate Change and Health Impacts
- Gastroesophageal reflux and treatments
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Helicobacter pylori-related gastroenterology studies
- Diverticular Disease and Complications
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Healthcare cost, quality, practices
- Medical Device Sterilization and Disinfection
- Dysphagia Assessment and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- COVID-19 Clinical Research Studies
- Healthcare and Environmental Waste Management
Dartmouth–Hitchcock Medical Center
2016-2025
White River Junction VA Medical Center
2016-2025
Dartmouth College
2014-2024
University of Vermont Medical Center
2024
Dartmouth Psychiatric Research Center
2023
RELX Group (Netherlands)
2020-2022
University of Zurich
2020
Hartford Financial Services (United States)
2020
Dartmouth Institute for Health Policy and Clinical Practice
2014-2019
Sociedad Española de Patología Digestiva
2019
The incidence of esophageal adenocarcinoma is rising dramatically. This increase may reflect increased disease burden, reclassification related cancers, or overdiagnosis resulting from diagnostic intensity, particularly upper endoscopy for patients with gastroesophageal reflux Barrett esophagus.We used the National Cancer Institute's Surveillance, Epidemiology, and End Results database to extract information on incidence, stage distribution, disease-specific mortality as well cancers.From...
Abstract Background: A steep increase in the incidence of esophageal adenocarcinoma has been observed between 1973 and 2001, but recent trends have not reported. Our aim was to examine incidence. Methods: We used Surveillance Epidemiology End Results database National Cancer Institute identify all patients who were diagnosed with 2006. Incidence analyzed for overall by stage using joinpoint regression. Results: Overall increased from 3.6 per million 25.6 trend analysis, however, suggests...
Abstract We are currently living in the throes of COVID-19 pandemic that imposes a significant stress on health care providers and facilities. Europe is severely affected with an exponential increase incident infections deaths. The clinical manifestations can be subtle, encompassing broad spectrum from asymptomatic mild disease to severe respiratory illness. Health professionals endoscopy units at increased risk infection COVID-19. Infection prevention control has been shown dramatically...
Confocal laser endomicroscopy (CLE) is rapidly emerging as a valuable tool for gastrointestinal endoscopic imaging. Fluorescent contrast agents are used to optimize imaging with CLE, and intravenous fluorescein the most widely agent. Fluorescein FDA-cleared diagnostic angiography of retina. For these indications, safety profile has been well-documented; however, date, not cleared use CLE.To estimate rate serious total adverse events attributable when CLE.We performed cross sectional survey...
Abstract Climate change and the destruction of ecosystems by human activities are among greatest challenges 21st century require urgent action. Health care significantly contribute to emission greenhouse gases waste production, with gastrointestinal (GI) endoscopy being one largest contributors. This Position Statement aims raise awareness ecological footprint GI provides guidance reduce its environmental impact. The European Society Gastrointestinal Endoscopy (ESGE) Gastroenterology Nurses...
Procedure-intense specialties, such as surgery or endoscopy, are a major contributor to the impact of healthcare sector on environment. We aimed measure amount waste generated during endoscopic procedures and understand changing from reusable single use endoscopes in USA.We conducted 5-day audit (cross-sectional study) all endoscopies performed at two US academic medical centres with low high endoscopy volume (2000 13 000 annually, respectively). calculated average disposable (excluding...
Background & AimsArtificial intelligence (AI)–based optical diagnosis systems (CADx) have been developed to allow pathology prediction of colorectal polyps during colonoscopies. However, CADx not yet validated for autonomous performance. Therefore, we conducted a trial comparing AI AI-assisted human (AI-H) diagnosis.MethodsWe performed randomized noninferiority patients undergoing elective colonoscopies at 1 academic institution. Patients were into (1) AI-based diminutive without input or...
Colonoscopy is an established method of colorectal cancer screening, but has adenoma miss rate 10-20%. Detection rates are expected to improve with optimised visualisation methods. This prospective randomised study evaluated narrow-band imaging (NBI), a new technique that may enhance image contrast in colon detection.Eligible patients presenting for diagnostic colonoscopy were randomly assigned undergo wide-angle using either conventional high-resolution or NBI during instrument withdrawal....
The biggest challenge in endoscopic surveillance of Barrett's oesophagus is better detection neoplasia mucosa normal macroscopic appearance. We evaluated vivo miniprobe confocal laser microscopy (CLM) for the invisible neoplasia.Prospective two-centre trial two phases: phase I to establish criteria and II test these criteria.296 biopsy sites 38 consecutive patients with (mean age 62.1 years, 89.5% men, median length oesophagus, 3 cm) were examined standard high-resolution endoscopy by CLM,...
It is assumed that esophageal adenocarcinoma the end result of a stepwise disease process transitions through gastroesophageal reflux (GERD) and Barrett's esophagus. The aim this study was to examine at what stage known risk factors exert their influence toward progression cancer.We enrolled 113 consecutive outpatients without GERD, 188 with 162 esophagus, 100 or high-grade dysplasia (HGD). All patients underwent standard upper endoscopy completed standardized questionnaire about social...
<h3>Objective</h3> Although it is well understood that the risk of oesophageal adenocarcinoma increases with Barrett length, transition risks for cancer associated different lengths are unknown. We aimed to estimate annual rates patients long-segment (≥3 cm), short-segment (≥1 <3 cm) and ultra-short-segment (<1 Barrett9s oesophagus. <h3>Design</h3> used three data sources each length category: (1) distribution long, short ultra-short oesophagus among a large German cohort newly...
<h3>Background & Aims</h3> Thermal treatment of the defect margin after endoscopic mucosal resection (EMR) large nonpedunculated colorectal lesions reduces recurrence rate. Both snare tip soft coagulation (STSC) and argon plasma (APC) have been used for thermal treatment, but there are few data directly comparing STSC with APC this indication. <h3>Methods</h3> We performed a randomized 3-arm trial in 9 US centers no (control) defects EMR ≥15 mm. The primary end point was presence residual...
Including carbon footprint as an end point in randomized, controlled trials could help clinicians, regulators, and policymakers understand the environmental effects of medical interventions.
Abstract Background Gastrointestinal (GI) endoscopy is one of healthcare’s main contributors to climate change. We aimed assess healthcare professionals’ attitudes and the perceived barriers implementation sustainable GI endoscopy. Methods The LEAFGREEN web-based survey was a cross-sectional study conducted by European Society Endoscopy (ESGE) Green Working Group. questionnaire comprised 39 questions divided into five sections (respondent demographics; change sustainability beliefs; waste...
Background and study aims: Surveillance of Barrett's esophagus includes endoscopic inspection with biopsy suspicious lesions followed by four-quadrant the remaining mucosa. We assessed ability probe-based confocal laser endomicroscopy (pCLE) to replace in evaluation patients a prospective controlled setting.