A5082233642- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Gastroesophageal reflux and treatments
- Long-Term Effects of COVID-19
- Lung Cancer Research Studies
- Gastrointestinal motility and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Liver Disease and Transplantation
- Metabolism, Diabetes, and Cancer
- Intestinal Malrotation and Obstruction Disorders
University of Miami
2020-2025
Jackson Memorial Hospital
2020-2021
Virginia Mason Medical Center
2018-2019
NewYork–Presbyterian Hospital
2011-2018
Columbia University Irving Medical Center
2017-2018
New York Hospital Queens
2011-2018
Columbia University
2007-2017
Icahn School of Medicine at Mount Sinai
2011-2017
Mount Sinai Hospital
2015
Mount Sinai Medical Center
2013
Objective Endoscopic pyloromyotomy (G-POEM) is a minimally invasive treatment option with promising uncontrolled outcome results in patients gastroparesis. Design In this prospective randomised trial, we compared G-POEM sham procedure severe The primary was the proportion of success (defined as decrease Gastroparesis Cardinal Symptom Index (GCSI) by at least 50%) 6 months. Patients to group persistent symptoms were offered cross-over G-POEM. Results enrolment stopped after interim analysis...
Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease. Diabetes mellitus (DM) is both risk factor for and sequela of PDAC. Metformin commonly prescribed biguanide oral hypoglycemic used the treatment type II DM. We investigated whether metformin use before PDAC diagnosis affected survival patients with DM, controlling confounders such as diabetic severity.We Surveillance, Epidemiology, End Results registry (SEER)-Medicare linked database to identify diagnosed between 2007...
Stenotrophomonas maltophilia is a multiple-antibiotic-resistant opportunistic pathogen that being isolated with increasing frequency from patients health-care-associated infections and especially cystic fibrosis (CF). While clinicians feel compelled to treat involving this organism, its potential for virulence not well established. We evaluated the immunostimulatory properties overall of clinical isolates S. using well-characterized Pseudomonas aeruginosa PAO1 as control. The CF were...
The coronavirus disease 2019 (COVID-19) pandemic has abruptly reduced gastrointestinal endoscopy activity worldwide. This had a consequent impact on training in the United Kingdom (UK). However, trainee procedure exposure not been quantified. We conducted UK-wide survey with aim of quantifying COVID-19 hands-on procedures performed by trainees and their emotional well-being. A 37-item (Supplementary File) was developed as part an international collaborative (EndoTrain).1Pawlak K.M. et...
<title>Abstract</title> <bold>BACKGROUND</bold> The development of acute pancreatitis is the most common serious complication endoscopic retrograde cholangiopancreatography (ERCP). <bold>AIMS</bold> We aimed to determine association between frailty status and outcomes in patients with post-ERCP (PEP). <bold>METHODS</bold> performed a cohort study using merged data from 2016 2017 National Inpatient Sample (NIS) database. International Classification Diseases (ICD), Tenth Revision, Clinical...
Options for the endoscopic management of symptomatic pancreatic fluid collections (PFCs) include transmural drainage (TM) alone, transpapillary (TP) or a combination both method (CD). There have been conflicting reports about best method. This study performed meta-analysis to determine whether CD presents an added clinical benefit over TM.The included studies compared TM with and reported success methods. A random-effects model was used pooled odds ratios (ORs) 95% confidence intervals (CIs)...
Background Assessment of mucosal visualization during esophagogastroduodenoscopy (EGD) can be improved with a standardized scoring system. To address this need, we created the Toronto Upper Gastrointestinal Cleaning Score (TUGCS). Methods We developed TUGCS using Delphi methodology, whereby an international group endoscopy experts iteratively rated their agreement proposed items and anchors on 5-point Likert scale. After each round, analyzed responses refined 80 % threshold for consensus....
We compared outcomes between use of 15 vs. 20 mm lumen-apposing metal stents (LAMSs) in endoscopic ultrasound-guided gastroenterostomy (EUS-GE) for gastric outlet obstruction.Databases were queried studies that used LAMS EUS-GE to relieve obstruction, and a proportional meta-analysis was performed.Thirteen included. The had pooled technical success rates 93.2% (95% confidence interval [CI], 90.5%-95.2%) 92.1% CI, 68.4%-98.4%), clinical 88.6% 85.4%-91.1%) 89.6% 79.0%-95.1%), adverse event...
Objectives Studies demonstrate safety and survival benefits of surgical resection in older individuals with pancreatic adenocarcinoma. We investigated treatment disparities by age. Methods The Surveillance, Epidemiology, End Results database for adenocarcinoma between 1983 2007 stratified age: younger than 50 years, 70 or years. Kaplan-Meier curves Cox proportional hazards models were used differences, logistic regression the decision to refuse surgery. A total 45,509 patients had...
In response to the coronavirus disease 2019 (COVID-19) pandemic, endoscopic procedures in hospital-based or freestanding facilities were cancelled delayed.1CDC COVID-19 Response TeamCharacteristics of health care personnel with COVID-19—United States, February 12–April 9, 2020.MMWR Morb Mortal Wkly Rep. 2020; 69: 477-481Crossref PubMed Scopus (570) Google Scholar Accordingly, endoscopy units have had act rapidly protect both staff and patients, weighing safety performing urgent against risk...
Abstract Background The prevalence and significance of digestive manifestations in COVID-19 remain uncertain. Methods Consecutive patients hospitalized with were identified across a geographically diverse alliance medical centers North America. Data pertaining to baseline characteristics, symptomatology, laboratory assessment, imaging, endoscopic findings from the time symptom onset until discharge or death manually abstracted electronic health records characterize prevalence, spectrum,...
Few studies have assessed the interaction between pain treatment and mortality in pancreatic cancer. The aim of this study was to investigate association receipt opioid prescriptions survival adults with cancer.The SEER-Medicare linked database used identify patients diagnosed late-stage cancer 2007 2015. Kaplan-Meier models were assess year after diagnosis survival. Cox proportional hazard determine survival, adjusting for propensity score other relevant confounders including...
Abstract BACKGROUND: Several environmental risk factors are known to predispose individuals pancreatic cancer, and up 15% of cancers have an inherited component. Understanding metachronous cancer associations can modify pancreas risk. The objective this study was investigate the association nonpancreatic with subsequent adenocarcinoma. METHODS: authors used data from US Surveillance, Epidemiology, End Results (SEER) registries identify 1,618,834 who had a primary malignancy adenocarcinoma (n...
Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has impacted endoscopy services and education worldwide. This study aimed to characterize the impact of COVID-19 on gastroenterology trainees in Canada. Methods An analysis Canadian respondents from international EndoTrain survey, open April 11 May 2 2020 distributed by program directors, trainees, national societies’ representatives, was completed. survey included questions monthly volume, personal protective equipment...
Abstract Previous studies have suggested that β-adrenergic signaling may regulate the growth of various cancers. The aim our study is to investigate association between incidental use beta-blockers for conditions on overall survival patients with pancreatic ductal adenocarcinoma (PDAC). Patients histologically-confirmed PDAC 2007 and 2011 were extracted from Surveillance, Epidemiology, End Results registry (SEER)-Medicare linked database. Kaplan Meier multivariable Cox Proportional-Hazard...