- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Organ and Tissue Transplantation Research
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Heart Failure Treatment and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
Cleveland Clinic
2016-2025
Cleveland Foundation
2024
Morristown Medical Center
2021
Atlantic Health System
2021
Minneapolis Heart Institute Foundation
2021
Cleveland Clinic Florida
2021
Columbia University Irving Medical Center
2013-2020
San Diego Cardiac Center
2020
Cardiovascular Research Foundation
2020
Clinical Research Institute
2014-2019
Based on randomized trials using first-generation devices, transcatheter aortic valve replacement (TAVR) is well established in the treatment of high-risk (HR) patients with severe stenosis (AS). To date, there a paucity adjudicated, prospective data evaluating outcomes newer generation devices and lower risk patients. We report early large, multicentre registry inoperable, HR, intermediate-risk (IR) undergoing next-generation SAPIEN 3 heart (THV). Patients severe, symptomatic AS (583 high...
In the initial PARTNER trial (Placement of Aortic Transcatheter Valves) transcatheter aortic valve replacement for high-risk (HR) and inoperable patients, mortality at 1 year was 24% in HR 31% patients. A recent report 30-day outcomes with low-profile SAPIEN 3 system demonstrated very low rates adverse events, but little is known about longer-term this device.Between October 2013 September 2014, 583 (65%) or (35%) patients were treated via transfemoral (84%) transapical/transaortic (16%)...
Perforation of a coronary venous branch for pericardial insufflation carbon dioxide (CO2) enhances safety epicardial access. The multiple procedural steps and length the procedure remain major limitation this approach impacting its routine clinical adoption. This study describes novel streamlined technique CO2 via radiofrequency (RF)-assisted right atrial appendage (RAA) perforation. Between 2023 2024, 18 patients (age: 55 ± 11 years; left ventricular ejection fraction: 44 13%) underwent...
Cameron lesions represent linear gastric erosions and ulcers on the crests of mucosal folds in distal neck a hiatal hernia (HH).Such may be found upto 50% endoscopies performed for another indication.Though typically asymptomatic, these rarely present as acute, severe upper gastrointestinal bleed (GIB).The aim is to report case non-anemic 87-year-old female with history HH atrial fibrillation who presented hematemesis melena resulting hypovolemic shock.Repeat esophagogastroduodenoscopy was...
Background Protamine is widely used to reverse the anticoagulant effects of heparin. Although mild thrombocytopenia common in patients given protamine after cardiac procedures, acute severe has not been described. We encountered a patient who experienced profound and bleeding shortly administration performed studies characterize responsible mechanism. Study Design Methods Patient serum was studied for antibodies that recognize protamine, heparin‐protamine complexes, platelets ( PLT s)...
Aims On the basis of evidence from autopsy studies, it is accepted that compensatory enlargement (remodelling) coronary arteries during progression atherosclerosis diminishes once atheroma burden (cross-sectional area stenosis) reaches ∼40%. Our aim was to evaluate whether a limiting factor for arterial remodelling using in vivo serial intravascular ultrasound (IVUS). Methods and results From cohort Reversal Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial, we identified 210...
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Video 1Endoscopic ultrasound-guided fine-needle biopsy of an intraventricular mass in a patient with ventricular tachycardia.