- Gastroesophageal reflux and treatments
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Eosinophilic Esophagitis
- Dysphagia Assessment and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- Testicular diseases and treatments
- Tracheal and airway disorders
- Diverticular Disease and Complications
- Cutaneous Melanoma Detection and Management
- Esophageal Cancer Research and Treatment
- Potassium and Related Disorders
- Gastrointestinal motility and disorders
- CAR-T cell therapy research
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
Albany Medical Center Hospital
2021-2025
St. George's University
2024
NYU Langone Health
2024
Washington University in St. Louis
2015-2021
Barnes-Jewish Hospital
2017-2020
Washington University Medical Center
2018
Harvard University Press
2008
Massachusetts General Hospital
2007
Harvard University
2007
Sleep disturbances are common, and perhaps even more prevalent in irritable bowel syndrome (IBS).To determine the effect of measured sleep on IBS symptoms following day, IBS-specific quality life (IBS-QOL) non-GI pain symptoms.IBS patients' patterns were compared to healthy individuals via wrist-mounted actigraphy over 7 days. Daily logs (severity, distress; 10-point Likert) stool pattern (Bristol scale) supporting (e.g. bloating, urgency; 5-point kept. Validated measures, including GI...
Section:ChooseTop of pageAbstract <<MATERIALS AND METHODSRESULTSDISCUSSIONReferencesCITING ARTICLES
Abstract Background Straight leg raise (SLR) while supine increases intra‐abdominal pressure. We hypothesized that elevations in pressure would transmit into the thoracic cavity if esophagogastric junction (EGJ) was disrupted. Methods Consecutive patients undergoing esophageal HRM were included they had adequate SLR (hip flexion with knees extended for ≥ 5 seconds supine). EGJ morphology subtyped based on lower sphincter (LES) and crural diaphragm (CD) location (type 1: LES CD overlap; type...
Abstract Background Straight leg raise (SLR) is a provocative maneuver that assesses esophagogastric junction (EGJ) barrier function during high‐resolution manometry (HRM). We evaluated the value of SLR in symptomatic reflux patients undergoing ambulatory monitoring. Methods Adult being for symptoms with esophageal physiologic testing off antisecretory therapy over 12 month period were studied. Demographics, clinical presentation, HRM studies, and monitoring studies analyzed. Intra‐abdominal...
Zouridis, Spyridon MD; Liu, Jacqueline Wadhwa, Niki Virk, Gurjiwan Hasak, Stephen MD, MPH Author Information
Acute esophageal necrosis is a gastrointestinal syndrome characterized by diffuse, circumferential, black-appearing mucosa of the distal esophagus and involves various lengths. It multifactorial condition involving hypoperfusion from low flow state, large reflux gastric contents, poor mucosal barrier. Complications involve stenosis or stricture perforation. Treatment often supportive with correction underlying conditions, aggressive fluid resuscitation, antacid therapy, restriction oral...
Genetic polymorphisms in G-protein beta-3 subunit (GNβ3) and beta-2 adrenergic receptor (ADRB2) are associated with pain gut hypersensitivity, which can overlap gastroesophageal reflux disease (GERD).