Girma Ayele

ORCID: 0000-0002-4476-370X
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Acute Myocardial Infarction Research
  • Cardiovascular Function and Risk Factors
  • Infective Endocarditis Diagnosis and Management
  • Blood groups and transfusion
  • Ion channel regulation and function
  • Kawasaki Disease and Coronary Complications
  • Pharmacological Effects and Toxicity Studies
  • Gastrointestinal disorders and treatments
  • Erythropoietin and Anemia Treatment
  • Coronary Interventions and Diagnostics
  • Coronary Artery Anomalies
  • Autoimmune Neurological Disorders and Treatments
  • Abdominal vascular conditions and treatments
  • Metabolism and Genetic Disorders
  • Cardiac Structural Anomalies and Repair
  • Bacillus and Francisella bacterial research
  • Aortic Disease and Treatment Approaches
  • Actinomycetales infections and treatment
  • Peripheral Artery Disease Management
  • Technology and Data Analysis
  • Dermatological diseases and infestations

Howard University
2022-2024

Howard University Hospital
2022-2024

University of Maryland, Baltimore
2022-2024

American University of Antigua
2022-2024

MedStar Heart & Vascular Institute
2024

University of Maryland Medical Center Midtown Campus
2022-2023

Daiichi Sankyo (United States)
2023

Wolkite University
2023

Medical Center Hospital
2023

Trinity Medical Center
2022

Based on randomized trials using first-generation devices, transcatheter aortic valve replacement (TAVR) is well established in the treatment of high-risk (HR) patients with severe stenosis (AS). To date, there a paucity adjudicated, prospective data evaluating outcomes newer generation devices and lower risk patients. We report early large, multicentre registry inoperable, HR, intermediate-risk (IR) undergoing next-generation SAPIEN 3 heart (THV). Patients severe, symptomatic AS (583 high...

10.1093/eurheartj/ehw112 article EN European Heart Journal 2016-03-31

After aortic valve replacement, left ventricular afterload is often characterized by the residual obstruction. Our objective was to determine whether higher systemic arterial afterload-as reflected in blood pressure, pulsatile and resistive load-is associated with adverse clinical outcomes after transcatheter replacement (TAVR).Total, pulsatile, load were measured 2141 patients severe stenosis treated TAVR PARTNER I trial (Placement of Aortic Transcatheter Valve) who had systolic pressure...

10.1161/circimaging.116.006308 article EN Circulation Cardiovascular Imaging 2017-07-01

Background Ubrogepant is a novel, oral calcitonin gene–related peptide (CGRP) receptor antagonist in development for the acute treatment of migraine. This trial evaluated safety and tolerability ubrogepant, focusing on hepatic safety, when administered intermittently with high-frequency dosing to healthy participants. Methods In this phase 1, multicenter, double-blind, parallel-group trial, adults (age 18–50 years) were randomized 1:1 placebo or ubrogepant. was dosed at 100 mg (2 × 50...

10.1177/0333102419869918 article EN cc-by-nc Cephalalgia 2019-09-19

<h3>Objective</h3> Pulmonary hypertension (PH) is associated with increased mortality after surgical or transcatheter aortic valve replacement (TAVR) for stenosis (AS), and when the pulmonary artery pressure particularly elevated, there may be questions about clinical benefit of TAVR. We aimed to identify haemodynamic factors TAVR among those moderate/severe PH. <h3>Methods</h3> Among patients symptomatic AS at high prohibitive risk receiving in Placement Aortic Transcatheter Valves...

10.1136/heartjnl-2015-308001 article EN Heart 2015-08-11

Background/ObjectiveOur objective is to highlight the importance of identifying symptoms SREAT, especially in setting intermittent cognitive dysfunction, and inform that SREAT can develop even patients with a history partial thyroidectomies.Case ReportWe present case 51-year-old female long-standing hypothyroidism presenting acute onset myoclonus, involuntary tremors, fatigue, malaise, palpitations for two weeks, lapses function. The patient’s workup completely within normal limits including...

10.1016/j.aace.2023.10.001 article EN cc-by-nc-nd AACE Clinical Case Reports 2023-10-07

Keto diet is defined as a high-fat, adequate-protein, and low-carbohydrate nutrition which forces the body to burn fats use an alternative metabolic fuel resource by stimulating endogenous ketone production. The standard range of ketones in ketosis up 3.00mmol/L, anything beyond this level can result serious medical conditions. This diet's most common easily reversible consequences are constipation, low-grade acidosis, hypoglycemia, kidney stones, increased lipid blood. We present case...

10.7759/cureus.36546 article EN Cureus 2023-03-22

Aspirin is promptly administered to patients presenting with acute coronary syndromes. It not known whether aspirin pretreatment in syndrome beneficial, particularly because some, but all, prior studies identified as an independent risk factor for adverse ischemic events. To study the effect of syndromes enrolled two large randomized clinical trials. Patients ACUITY and HORIZONS-AMI trials were analyzed according within 5–7 days before We evaluated incidence death, myocardial infarction,...

10.1177/2048872615624848 article EN European Heart Journal Acute Cardiovascular Care 2015-12-31

OPINION article Front. Public Health, 25 October 2022Sec. Health Education and Promotion Volume 10 - 2022 | https://doi.org/10.3389/fpubh.2022.1029823

10.3389/fpubh.2022.1029823 article EN cc-by Frontiers in Public Health 2022-10-25

Acute diverticulitis is a prevalent medical condition with increasing incidence rates. While the sigmoid colon most commonly affected part of large intestine, there have been occurrences right-sided although uncommon. We present case report highlighting atypical presentation in 27-year-old female patient. The patient experienced right upper and epigastric pain was ultimately diagnosed diverticulitis, supported by her CT imaging findings. This uncommon underscores importance considering...

10.7759/cureus.55674 article EN Cureus 2024-03-06

Trisomy 21 often leads to cardiac complications, usually associated with congenital heart disease, such as atrial septal defects, ventricular and patent ductus arteriosus. This case describes an unexpected instance of infective endocarditis (IE) in a middle-aged patient incidentally discovered foramen ovale (PFO). The common risk factors for IE include previous valve surgery, artificial valves, pacemakers, prior IE, defects like bicuspid aortic valve, IV drug use, the mentioned earlier.

10.7759/cureus.61106 article EN Cureus 2024-05-26

Hyperammonemia is a metabolic disorder characterized by supraphysiologic ammonia (NH3) concentrations in the blood. Although usually seen adults with liver disease, hyperammonemia notable complication 4.1% of lung transplants. It associated cerebral edema and neurological dysfunction carries up to 75% mortality critically ill patients. Opportunistic infections caused Mycoplasma Ureaplasma species have been implicated as cause this disturbance. Literature neonates has shown that renal...

10.7759/cureus.63607 article EN Cureus 2024-07-01

Latex-fruit syndrome is characterized by hypersensitivity reactions to certain plant-derived foods in individuals allergic natural rubber latex (NRL), affecting approximately 30-50% of NRL-allergic patients. This condition arises due the cross-reactivity IgE antibodies. Over time, this has been associated with an increased number plant sources, including avocado, banana, chestnut, kiwi, peach, tomato, potato, and bell pepper. We present a case art student who developed latex-fruit following...

10.7759/cureus.65002 article EN Cureus 2024-07-20

In 2021, US healthcare spending surpassed $4.3 trillion, about 18.3% of GDP, and is projected to grow over 5% annually until 2028 [1, 2]. The system, which often fails provide the best patient outcomes at lowest cost, fragmented inefcient. It organized around silos providers, payers, pharmacies, not centered on patients' needs, leading duplication, waste, poor care coordination. Built a fee-for-service payment model, system prioritizes service volume value quality [3]. Despite efforts link...

10.36106/gjra/9404627 article EN Global Journal For Research Analysis 2024-07-15

Patients with human immunodeciency virus (HIV) and acquired immune deciency syndrome (AIDS) have an increased risk of osteoporosis fractures when compared people the same age sex. As a result, vertebra, lumbar, hip is higher in living HIV to general population. This condition magnied setting renal failure superimposed metabolic bone disease. Here, we present case fracture patient long-standing, well-controlled disease kidney failure.

10.36106/gjra/0511402 article EN Global Journal For Research Analysis 2024-08-15

Rhabdomyolysis, a severe condition marked by the breakdown of muscle tissue, leads to release intracellular contents into bloodstream. This can be triggered range factors, including intense physical activity, traumatic injuries, certain medications, and infections. Diagnosis typically involves detecting elevated creatine phosphokinase (CPK) levels alongside characteristic clinical symptoms. Levetiracetam-induced rhabdomyolysis is an exceptionally rare phenomenon, with only few cases...

10.7759/cureus.74111 article EN Cureus 2024-11-20
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