A5077042611- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Gastroesophageal reflux and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cancer-related gene regulation
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Eosinophilic Esophagitis
- Metastasis and carcinoma case studies
- Epigenetics and DNA Methylation
- Lung Cancer Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Neuroendocrine Tumor Research Advances
- Minimally Invasive Surgical Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Genetic factors in colorectal cancer
- Optical Coherence Tomography Applications
- Tracheal and airway disorders
University Hospitals Cleveland Medical Center
2015-2025
University Hospitals of Cleveland
2015-2024
University School
2015-2024
Case Western Reserve University
2015-2024
University Hospitals Seidman Cancer Center
2018-2024
RELX Group (Netherlands)
2019-2024
Case Comprehensive Cancer Center
2009-2023
American Society for Gastrointestinal Endoscopy
2004-2023
Yale University
2009-2023
Brigham and Women's Hospital
2023
Barrett's esophagus, a condition of intestinal metaplasia the is associated with an increased risk esophageal adenocarcinoma. We assessed whether endoscopic radiofrequency ablation could eradicate dysplastic esophagus and decrease rate neoplastic progression.
<h3>Background</h3> Screening individuals at increased risk for pancreatic cancer (PC) detects early, potentially curable, neoplasia. <h3>Objective</h3> To develop consortium statements on screening, surveillance and management of high-risk with an inherited predisposition to PC. <h3>Methods</h3> A 49-expert multidisciplinary international met discuss screening vote statements. Consensus was considered reached if ≥75% agreed or disagreed. <h3>Results</h3> There excellent agreement that, be...
Preliminary research suggests that rectally administered nonsteroidal antiinflammatory drugs may reduce the incidence of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP).In this multicenter, randomized, placebo-controlled, double-blind clinical trial, we assigned patients at elevated risk for post-ERCP to receive a single dose rectal indomethacin or placebo immediately ERCP. Patients were determined be high on basis validated patient- and procedure-related factors....
To report pancreas surveillance outcomes of high-risk individuals within the multicenter Cancer Pancreas Screening-5 (CAPS5) study and to update patients enrolled in prior CAPS studies.
Importance Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with increasing incidence. The majority of PDACs are incurable at presentation, but population-based screening not recommended. Surveillance high-risk individuals for PDAC may lead to early detection, the survival benefit unproven. Objective To compare patients surveillance-detected US national data. Design, Setting, and Participants This comparative cohort study was conducted in multiple academic medical centers...
Background: Choledocholithiasis is a major source of morbidity among patients undergoing cholecystectomy for symptomatic gallstones. There no consensus on the best approach to diagnosing bile duct stones. We compared safety, accuracy, diagnostic yield, and cost EUS- ERCP-based approaches. Methods: Sixty-four consecutive pre- post-cholecystectomy referred endoscopic retrograde cholangiopancreatography (ERCP) suspected choledocholithiasis were prospectively evaluated in blinded fashion. All...
Background: Although familial clusters of Barrett's oesophagus and oesophageal adenocarcinoma have been reported, a predisposition to these diseases has not systematically investigated. Aims: To determine whether (or oesophagogastric junctional) aggregate in families. Patients methods: A structured questionnaire eliciting details on reflux symptoms, exposure history, family history was given Caucasian case (n=58) subjects with oesophagus, adenocarcinoma, or junctional control (n=106)...
Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most technically demanding and highestrisk procedures performed by gastrointestinal endoscopists. Hence, it requires significant focused training experience to maximize success safety (1, 2). ERCP has evolved from a purely diagnostic predominately therapeutic procedure (3). ancillary interventions are effective in nonsurgical management variety pancreaticobiliary disorders, commonly removal bile duct stones relief malignant...