A5022886338- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal Tumor Research and Treatment
- Cancer Genomics and Diagnostics
- Medical Device Sterilization and Disinfection
- Esophageal Cancer Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Amoebic Infections and Treatments
- Diverticular Disease and Complications
- Biliary and Gastrointestinal Fistulas
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Pain Management and Opioid Use
- Pediatric Pain Management Techniques
- Liver Disease and Transplantation
Orlando Health
2021-2025
Bristol-Myers Squibb (Germany)
2023
Pfizer (United States)
2023
Fujifilm (Japan)
2023
Boston Scientific (United States)
2023
Medtronic (Ireland)
2023
Creative Commons
2023
Olympus (Japan)
2023
Brigham and Women's Hospital
2023
American Society for Gastrointestinal Endoscopy
2023
Objective Although lumen-apposing metal stents (LAMS) are increasingly used for drainage of walled-off necrosis (WON), their advantage over plastic is unclear. We compared efficacy LAMS and WON drainage. Design Patients with were randomised to endoscopic ultrasound-guided using or stents. Primary outcome was comparing total number procedures achieve treatment success defined as symptom relief in conjunction resolution on CT at 6 months. Secondary outcomes success, procedure duration,...
Infected necrotizing pancreatitis is a highly morbid disease with poor outcomes. Intervention strategies have progressed from open necrosectomy to minimally invasive approaches. We compared outcomes of surgery vs endoscopic approaches for patients infected pancreatitis.We performed single-center, randomized trial 66 confirmed or suspected who required intervention May 12, 2014, through March 24, 2017. Patients were randomly assigned groups that received (laparoscopic video-assisted...
Lumen-apposing metal stents (LAMS) have been recently developed to improve treatment outcomes in the endoscopic management of pancreatic fluid collections (PFC), particularly walled-off necrosis (WON), facilitate better drainage necrotic contents and minimise risk perforation peritoneal leakage.In an ongoing randomised trial, we observed serious adverse events that included delayed bleeding, buried stent syndrome biliary stricture necessitated a change protocol for patients with PFC treated LAMS.
<b>Background and study aims:</b> The fanning technique for endoscopic ultrasound-guided fine-needle aspiration (EUS – FNA) involves sampling multiple areas within a lesion with each pass. aim of this was to compare the standard techniques EUS FNA solid pancreatic masses. <b>Patients methods: </b>Consecutive patients mass lesions were randomized undergo using either or technique. main outcome measure median number passes required establish diagnosis. secondary measures diagnostic accuracy,...
Studies on EUS-guided transmural biliary drainage (EUS-BD) have evaluated its efficacy as a rescue technique after failed ERCP. We performed single-center, single-blind, randomized trial to compare EUS-BD and ERCP primary treatment for distal obstruction in pancreatic cancer.Patients underwent (n = 33) or 34). The endpoint was the rate of adverse events. Secondary endpoints were technical success, success (defined decline serum bilirubin by 50% at 2-week follow-up), reinterventions,...
Recently, a 22-gauge (G) needle with Franseen tip design was developed for endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB). The present study evaluated the performance of in EUS-guided tissue acquisition.This is retrospective patients who underwent EUS-FNB using needle. Lesions were sampled either only or after failed diagnostic aspiration (FNA). After rapid onsite evaluation (ROSE), two dedicated passes carried out histological assessment cell block technique. Main outcomes...
Although lumen-apposing metal stents (LAMS) are increasingly being used for drainage of pancreatic fluid collections (PFC), their advantage over plastic is unclear.In this retrospective case-control study, 20 patients who underwent PFC using LAMS were matched with 40 treated according to type (walled-off necrosis [WON] vs pseudocyst) and procedural technique (conventional multi-gate). Main outcome measures treatment success, reintervention, clinical stent-related adverse events, duration,...
To study the effect of disconnected pancreatic duct syndrome (DPDS) on endoscopic management fluid collections (PFCs).Data impact DPDS in patients undergoing treatment PFCs are limited.Retrospective drainage from 2003 to 2015. If response was suboptimal following initial or ultrasound-guided transmural drainage, hybrid interventions (endoscopic multigate/dual modality technique, endoscopic/percutaneous sinus tract necrosectomy) were performed. Transmural stents left permanently situ 2008...
As cytological aspirates from endoscopic-ultrasound-guided fine needle aspiration (EUS-FNA) has limited diagnostic sensitivity and are suboptimal for molecular profiling morphological characterisation of certain neoplasms, a biopsy (FNB) with three-pronged (Franseen geometry) cutting edge been developed to procure histology. In randomised trial 46 patients pancreatic masses, procurement histological core tissue as evidenced by total tumour areas was significantly higher 22G FNB than FNA...
Background and Aim Fine‐needle aspiration (FNA) cytology has been the preferred technique for procuring tissue at endoscopic ultrasound (EUS) procedures past 25 years. To overcome some of limitations FNA cytology, fine‐needle biopsy (FNB) recently developed to yield histological tissue. Main objective was compare diagnostic FNB compared both onsite offsite specimen assessment. Methods A retrospective study conducted a single tertiary referral center evaluate outcomes over 4‐year period....
Although most postendoscopic retrograde cholangiopancreatography (ERCP) biliary tract infections are attributed to suboptimal ductal drainage, transmission of infection by contaminated reusable duodenoscopes has been reported. To overcome this limitation, a disposable duodenoscope recently developed. However, given the widespread use and large volume ERCPs being performed worldwide, financial viability novel concept is unclear. Utilising an activity-based costing model, we estimated that...
Treatment outcomes are suboptimal for patients undergoing endoscopic treatment of walled-off pancreatic necrosis (WOPN). The objective this study is to identify factors that impact in patient subset.This a retrospective with WOPN treated endoscopically over 10 years. Patients underwent placement stents and nasocystic catheters within the necrotic cavity. In select patients, multiple transluminal gateway technique (MTGT) was adopted create several openings stomach or duodenum facilitate...
Abstract Background The aim of the study was to compare outcomes patients with pancreatic or peripancreatic walled-off necrosis by endoscopy using conventional approach versus an algorithmic based on collection size, location and stepwise response intervention. Methods This observational before–after consecutive managed over two time intervals. In initial period (2004–2009) symptomatic underwent single transmural drainage placement stents a nasocystic catheter, followed direct endoscopic...