Hendrik Manner

ORCID: 0000-0003-0745-2336
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About
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Research Areas
  • Esophageal Cancer Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Esophageal and GI Pathology
  • Gastrointestinal Tumor Research and Treatment
  • Metastasis and carcinoma case studies
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Helicobacter pylori-related gastroenterology studies
  • Gastroesophageal reflux and treatments
  • Eosinophilic Esophagitis
  • Pancreatic and Hepatic Oncology Research
  • Genetic factors in colorectal cancer
  • Lung Cancer Treatments and Mutations
  • Public Administration and Political Analysis
  • Lung Cancer Diagnosis and Treatment
  • Dysphagia Assessment and Management
  • RNA modifications and cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Anesthesia and Sedative Agents
  • Lymphoma Diagnosis and Treatment
  • Tracheal and airway disorders
  • Multiple and Secondary Primary Cancers
  • Cancer-related gene regulation
  • Hemostasis and retained surgical items
  • Nausea and vomiting management

University Hospital Frankfurt
2020-2023

Goethe University Frankfurt
2020-2023

Klinikum Frankfurt Höchst
2018-2021

RELX Group (Netherlands)
2020

Helios Dr. Horst Schmidt Kliniken Wiesbaden
2009-2018

Helios Kliniken
2016

St. Marien Hospital
2014-2016

Kaiser Permanente
2015

Coventry University
2015

Johannes Gutenberg University Mainz
2006-2013

<h3>Objective:</h3> Endoscopic therapy is increasingly being used in the treatment of high-grade intraepithelial neoplasia (HGIN) and mucosal adenocarcinoma (BC) patients with Barrett’s oesophagus. This report provides 5 year follow-up data from a large prospective study investigating efficacy safety endoscopic these analysing risk factors for recurrence. <h3>Design:</h3> Prospective case series. <h3>Setting:</h3> Academic tertiary care centre. <h3>Patients:</h3> Between October 1996...

10.1136/gut.2007.142539 article EN Gut 2008-05-06

10.1053/j.gastro.2012.04.032 article EN Gastroenterology 2012-04-24

Esophagectomy has previously been the gold standard for patients with mucosal adenocarcinoma in Barrett's esophagus (Barrett's carcinoma, BC). Because of minimal invasiveness and excellent results obtained endoscopic resection (ER), latter become an accepted alternative. However, few data have so far published comparing 2 treatment methods.A total 114 BC who were treated surgically or endoscopically high-volume centers included this study. Between 1996 2009, 38 received transthoracic...

10.1097/sla.0b013e31821d4bf6 article EN Annals of Surgery 2011-04-29

BACKGROUND Endoscopic therapy (ET) has become a less risky alternative to open surgery in mucosal Barrett's cancer (BC) because of the very low risk lymph node (LN) metastasis. Recently published surgical series demonstrated that even case minimal submucosal invasion BC, for LN metastasis is low. In consequence, also these patients might be eligible curative ET. The aim this study was prospectively evaluate efficacy and safety endoscopic resection (ER) patients. METHODS From September 1996...

10.1111/j.1572-0241.2008.02083.x article EN The American Journal of Gastroenterology 2008-09-10

OBJECTIVES: Double-balloon enteroscopy (DBE) is now an established method for diagnostic and therapeutic small-bowel endoscopy. Single-balloon (SBE) has been introduced to simplify the technique. A prospective randomized study was carried out compare two methods. METHODS: The included 100 patients (50 in each group; 63 men, 37 women; mean age 55 years), with no previous or colon surgery. indications were (suspected) mid-gastrointestinal bleeding, Crohn's disease, masses, chronic diarrhea...

10.1038/ajg.2009.712 article EN The American Journal of Gastroenterology 2010-01-05

<h3>Objective</h3> Although it is well understood that the risk of oesophageal adenocarcinoma increases with Barrett length, transition risks for cancer associated different lengths are unknown. We aimed to estimate annual rates patients long-segment (≥3 cm), short-segment (≥1 &lt;3 cm) and ultra-short-segment (&lt;1 Barrett9s oesophagus. <h3>Design</h3> used&nbsp;three data sources each length category: (1) distribution long, short ultra-short oesophagus among a large German cohort newly...

10.1136/gutjnl-2015-309220 article EN Gut 2015-06-25

Vascular malformations are the most common sources of bleeding in small bowel. They can be treated with argon plasma coagulation (APC) during double-balloon enteroscopy (DBE). This study aimed to evaluate long-term follow-up effectiveness APC for small-bowel by means a single-center retrospective study.Between June 2003 and December 2005, treatment lesions was carried out DBE 63 patients known or suspected mid-gastrointestinal bleeding. Fifty were included analysis. Main outcome measurements...

10.1055/s-0030-1256388 article EN Endoscopy 2011-05-03

<b>Background and study aim:</b> It is commonly assumed that ablation of any remaining Barrett’s epithelium after endoscopic resection early neoplasia improves outcome by reducing the rate metachronous lesions, but this has not yet been evaluated in a randomized trial. The aim was to compare argon plasma coagulation (APC) with surveillance only for management residual following resection. <b>Patients methods:</b> Patients whom focal (high grade intraepithelial [HGIN] or mucosal cancer) had...

10.1055/s-0033-1358813 article EN Endoscopy 2013-12-18

Sedation has been established for GI endoscopic procedures in most countries, but it is also associated with an added risk of complications. Reported complication rates are variable due to different study methodologies and often limited sample size.Acute sedation-associated complications were prospectively recorded electronic endoscopy documentation 39 centres between December 2011 August 2014 (median inclusion period 24 months). The sedation regimen was decided by each centre.A total 368...

10.1136/gutjnl-2015-311037 article EN Gut 2018-01-03

See also: Commentaire de "Traitement endoscopique du diverticule Zenker: le choix des armes", pp. 141, 131, 137, 146Endoscopy 2007; 39(02): 193-193DOI: 10.1055/s-0032-1306914

10.1055/s-2007-966164 article FR Endoscopy 2007-02-27

See also: Commentaire de travail A. May et al., pp. 477Endoscopy 2011; 43(06): 743-743DOI: 10.1055/s-0031-1291778

10.1055/s-0030-1256340 article EN Endoscopy 2011-03-24

Complete reversal of Barrett's epithelium (BE) achieved by treatment with argon plasma coagulation (APC) is variable. The aim this prospective study was to evaluate the effectiveness high-power APC in a multicenter trial.In seven centers, 60 patients (mean age 57, range 27-77) nonneoplastic BE (length 1-8 cm) were recruited for (90 W) combination esomeprazole 80 mg/day. Video endoscopy, chromoendoscopy, and four-quadrant biopsies (4QB) carried out during baseline endoscopy regular intervals....

10.1111/j.1572-0241.2006.00709.x article EN The American Journal of Gastroenterology 2006-07-01

See also: Commentaire de travail A. May et al., pp. 606Endoscopy 2007; 39(07): 757-758DOI: 10.1055/s-0032-1306952

10.1055/s-2007-966640 article EN Endoscopy 2007-07-05

Thermal ablation for Barrett's oesophagus has widely been established in gastrointestinal endoscopy during the last decade. The mainly used methods of radiofrequency (RFA) and argon-plasma coagulation (APC) carry a relevant risk stricture formation up to 5-15%. Newer techniques that are able overcome this disadvantage would therefore be desirable. aim present study was compare depth tissue injury new method Hybrid-APC versus standard APC within randomized porcine model.Using total eight...

10.1177/2050640614544315 article EN other-oa United European Gastroenterology Journal 2014-07-30
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