- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Genetic factors in colorectal cancer
- Gallbladder and Bile Duct Disorders
- Colorectal and Anal Carcinomas
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Gastrointestinal disorders and treatments
- Diverticular Disease and Complications
- Helicobacter pylori-related gastroenterology studies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroendocrine Tumor Research Advances
- Geological formations and processes
- Mycobacterium research and diagnosis
- Lung Cancer Research Studies
- Geology and Paleoclimatology Research
- Lymphoma Diagnosis and Treatment
National Cancer Center Hospital East
2016-2025
Kure Medical Center
2024
National Hospital Organization
2024
Tokyo National Hospital
2011-2023
Hochschule Düsseldorf University of Applied Sciences
2016-2023
University of Tübingen
2016-2023
Beth Israel Deaconess Medical Center
2023
American Society for Gastrointestinal Endoscopy
2023
Penn State Milton S. Hershey Medical Center
2023
Rutgers, The State University of New Jersey
2023
Most of the esophageal squamous cell carcinomas (ESCCs) and cancers head neck (H&N) region are diagnosed at later stages. To achieve better survival, early detection is necessary. We compared real-time diagnostic yield superficial cancer in these regions between conventional white light imaging (WLI) narrow band (NBI) high-risk patients.In a multicenter, prospective, randomized controlled trial, 320 patients with ESCC were randomly assigned to primary WLI followed by NBI (n = 162) or 158)...
Background: Computer-aided diagnosis (CAD) for colonoscopy may help endoscopists distinguish neoplastic polyps (adenomas) requiring resection from nonneoplastic not resection, potentially reducing cost. Objective: To evaluate the performance of real-time CAD with endocytoscopes (×520 ultramagnifying colonoscopes providing microvascular and cellular visualization colorectal after application narrow-band imaging [NBI] methylene blue staining modes, respectively). Design: Single-group,...
Background Magnifying Narrow Band Imaging (NBI) during colonoscopy is a reliable method for differential and depth diagnoses of colorectal lesions. This study examined the diagnostic yield magnifying NBI based on Japan Expert Team (JNET) classification in clinical setting using large‐scale practice database. Types 1, 2A, 2B 3 correspond to histopathological classifications hyperplastic polyp/sessile‐serrated polyp, low‐grade intramucosal neoplasia, high‐grade neoplasia/shallow submucosal...
Artificial intelligence (AI) tools aimed at improving polyp detection have been shown to increase the adenoma rate during colonoscopy. However, it is unknown how increased rates by AI affect burden of patient surveillance after removal.We conducted a pooled analysis 9 randomized controlled trials (5 in China, 2 Italy, 1 Japan, and United States) comparing colonoscopy with or without aids. The primary outcome was proportion patients recommended undergo intensive (ie, 3-year interval). We...
Comprehensive genomic profiling (CGP) has been approved in Japan since June 2019, enabling mutation-specific therapy. Although tissue sampling via endoscopic ultrasound-guided acquisition (EUS-TA) is standard pancreatic cancer, reports on obtaining appropriate samples for CGP, especially the OncoGuide NCC Oncopanel System (NOP) and FoundationOne CDx (FOne), are lacking. Therefore, we investigated success rate factors related to EUS-TA CGP analysis suitability unresectable ductal...
To verify the value of pathological criteria for additional treatment in locally resected pT1 colorectal carcinoma (CRC) which have been used Japanese Society Cancer Colon and Rectum (JSCCR) guidelines since 2009.
When a large flat colorectal tumor is excised by piecemeal endoscopic resection, it not possible to obtain suitable specimens for histopathological examination assess whether the resection has been complete. We prospectively analysed follow-up colonoscopy examinations of polypectomy sites residual lesions.A total 24 patients with tumors were treated using an submucosal saline injection technique. The site was examined lesions magnifying colonoscope, at 3, 6, 12 and months...
Head and neck cancer, especially pharyngeal frequently co-exist with esophageal but cancer has proven difficult to detect in such cases before its progression an advanced stage. Several recent reports have indicated that narrow-band imaging (NBI) endoscopy magnification is able improve the detection of superficial cancer. NBI a relatively new optical technology based on limiting depth light penetration into mucosa. The recognition these lesions dramatically improved microvascular structure...
Objectives Endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) for solid pancreatic lesions has high diagnostic yield. However, few prospective multicenter studies have been performed. We performed a cohort study to evaluate the efficacy and safety of EUS‐FNA diagnosis lesions. Methods This involved five hospitals in Japan. The primary outcome was sensitivity diagnosing malignant also evaluated parameters sufficiency EUS‐FNA. Results In total, 246 patients were enrolled. absolute...
Abstract Background This study aimed to demonstrate the feasibility of endoscopic hand-suturing (EHS) and attainability sustained closure after colorectal submucosal dissection (ESD). Methods EHS was defined as uninterrupted suturing mucosal defect ESD using an absorbable barbed suture a through-the-scope needle holder. Following individual training ex vivo porcine colonic model, two experienced endoscopists performed EHS. Repeat colonoscopy on third or fourth day examine site. The primary...
INTRODUCTION: There is considerable concern about whether endoscopic resection (ER) before additional surgery (AS) for T1 colorectal cancer (CRC) has oncologically potential adverse effects. Therefore, the aim of this study was to compare long-term outcomes, including overall survival (OS), patients treated with AS after ER vs primary (PS) CRC using a propensity score-matched analysis from large observational study. METHODS: This investigated 6,105 either or surgical between 2009 and 2016 at...
Objectives We aimed to determine the compliance, safety, and acceptance of colon capsule endoscopy (CCE) small bowel (SBCE) in an out‐of‐clinic setting remotely supported by medical staff. Methods enrolled 30 examinees (24 with CCE six SBCE) who had not undergone CE at gastroenterological centers. All were provided instructions on equipment preparations. Results was performed home ( n = 16) or workplace 8). Compliance data‐recorder alerts 100% for preparation 79% operation. Total colonoscopy...
Introduction: Eosinophilic gastrointestinal disease (EGID) is divided into eosinophilic esophagitis (EoE) and non-eosinophilic (non-EoE-EGID), based on the involved organs. The present survey was performed to provide an overview of current status epidemiology, diagnosis, treatment EGID in Asia. Methods: Responses questionnaire were obtained from 228 doctors at various institutions eight Asian countries. consisted 52 questions EoE non-EoE EGID. Results: Questionnaire most common participation...