- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Colorectal Cancer Screening and Detection
- Gastrointestinal Bleeding Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Diverticular Disease and Complications
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Cardiac Arrhythmias and Treatments
- Gastrointestinal motility and disorders
- Tracheal and airway disorders
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Mycobacterium research and diagnosis
- Microscopic Colitis
- Venous Thromboembolism Diagnosis and Management
- Liver Disease and Transplantation
Teikyo University
2018-2025
University of Tokyo Hospital
2006-2022
The University of Tokyo
2011-2022
The Japanese Society of Gastroenterological Surgery
2018-2021
Showa University
2020
Jikei University School of Medicine
2020
Iwate Medical University
2020
MSD K.K. (Japan)
2017-2018
Olympus (Japan)
2016
University Gastroenterology
2016
Background and aims: Endoscopic submucosal dissection (ESD) provides a high en bloc resection rate with less invasiveness than surgical for large or scarring gastrointestinal neoplasms. However, detailed outcomes in colorectal ESD are still lacking. The aim of our study was to elucidate short- long-term ESD.
See also: Commentaire de travail O. Goto et al., pp. 118Endoscopy 2009; 41(02): 250-251DOI: 10.1055/s-0032-1306729
Background and study aims: Endoscopic submucosal dissection (ESD) is a novel technique used for the treatment of gastrointestinal neoplasia. One its major limitations, however, complication perforation. Patients methods: We included in our all cases perforation that occurred during ESD procedures epithelial neoplasia between February 2000 2005. Clinical outcomes after were investigated. Results: Perforation was experienced at 27 lesions patients (four esophagus, fourteen stomach, seven...
Endoscopic submucosal dissection (ESD) has become a widely accepted method for treating gastrointestinal neoplasms. The objective of our study was to assess the learning curve ESD gastric epithelial neoplasms.Clinicopathological data were retrospectively collected from 383 procedures neoplasms that performed over 5-year period. Thirteen endoscopists involved as operators during this In 1, performance two principal assessed every 25 patients. 2, all 13 according their experience.In caseloads...
<b>Background and study aims:</b> Suitable techniques for the prevention of stricture formation after esophageal endoscopic submucosal dissection (ESD) are still lacking. We investigated efficacy polyglycolic acid (PGA) sheets with fibrin glue to prevent post-ESD stricture. <b>Patients methods:</b> conducted a pilot on total eight consecutive patients who underwent ESD that left mucosal defect more than three-quarters circumference. PGA were attached immediately completion ESD. The primary...
Fatty liver disease (FLD) including non-alcoholic fatty (NAFLD), a rapidly emerging and widely recognized today, is regarded as hepatic manifestation of metabolic syndrome. Helicobacter pylori, one the most common pathogens worldwide, has been reported to be associated with syndrome, but whether there direct association FLD yet unclear. The aim this study was clarify NAFLD causative background factors pylori infection.This cross-sectional Japanese adults who received medical checkups at...
Background Despite the marked increase of diverticulosis, its risk factors have not been adequately elucidated. We therefore aim to identify significantly associated with diverticulosis. also investigate present state diverticulosis in Japan. Methods reviewed medical records from 1990 2010 that included data consecutive 62,503 asymptomatic colonoscopy examinees general population Most recent 3,327 were analyzed 16 background factors. Results Among subjects (47,325 men and 15,178 women; 52.1...
Endoscopic mucosal resection (EMR) is the gold standard for treatment of noninvasive large colorectal lesions, despite challenges associated with nonlifting lesions and a high rate local recurrence. submucosal dissection (ESD) offers possibility overcoming these EMR limitations. However, higher risk complications longer procedure time prevented its dissemination. As ESD now provides more stable results because standardized techniques compared those used earlier, this study aimed to quantify...
The technique of endoscopic submucosal dissection (ESD) has recently been developed for en-bloc resection gastric tumors. For oncological reasons and in order to improve the patients' quality life, it may be desirable use same rectal neoplasia.Thirty-five consecutive patients with neoplasia who had a preoperative diagnosis large intraepithelial neoplasias fibrosis or located on folds were enrolled. ESD was carried out previously described stomach, some modifications. efficacy, complications,...
Background and Study Aims: The esophagogastric junction (EGJ) has been considered a difficult location for endoscopic treatment of tumors, due to its narrow lumen sharp angle. Endoscopic submucosal dissection (ESD) is method resection, capable removing large tumors in an en bloc fashion. aim this study was evaluate the efficacy safety ESD EGJ tumors. Patients Methods: For 30 lesions treated by ESD, size resected specimens, resection rate, complications, local recurrence were assessed....
Gastroesophageal reflux disease (GERD) is a very common disorder worldwide, comprised of esophagitis (RE) and non-erosive (NERD). As more than half GERD patients are classified into the NERD group, precise evaluation bothersome epigastric symptoms essential. Nevertheless, compared with many reports targeting endoscopic esophagitis, large-scale studies focusing on have been scarce. To elucidate lifestyle factors affecting symptoms, 19,864 healthy adults in Japan were analyzed. Sub-analyses...
Endoscopic submucosal dissection (ESD) has gradually gained acceptance as one of the standard treatments for early esophageal cancer, well gastric cancer in Japan, but standardization knowledge is still incomplete. The final goal to perform ESD not resect lesion an en bloc fashion, save patient from cancer-related death. Thus, indications should be considered based on entire patient, just target itself, and pre-, peri- postoperative management also very important, technical aspects ESD. In...
To clarify the effectiveness of second-look endoscopy (SLE) at preventing bleeding after gastric endoscopic submucosal dissection (ESD).A multicentre prospective randomised controlled non-inferiority trial was conducted five referral institutions across Japan. Patients with a solitary neoplasm were enrolled. Exclusion criteria previous oesophagogastric surgery or radiation therapy; perforation and administration antithrombotics, steroids non-steroidal anti-inflammatory drugs. assigned to SLE...
Background Despite the high prevalence of gastroesophageal reflux disease (GERD), its risk factors are still a subject controversy. This is probably due to inadequate distinction between esophagitis (RE) and non-erosive (NERD), also evaluation adjacent stomach. Our aim therefore define background RE NERD independently, based on Helicobacter pylori infection gastric atrophy. Methods We analyzed 10,837 healthy Japanese subjects (6,332 men 4,505 women, aged 20–87 years) who underwent upper...