Matthias Löhr
A5067118869- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- IgG4-Related and Inflammatory Diseases
- Cancer Immunotherapy and Biomarkers
- Pancreatic function and diabetes
- Cancer Cells and Metastasis
- CAR-T cell therapy research
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Diabetes and associated disorders
- Renal cell carcinoma treatment
- Esophageal and GI Pathology
- Psychiatric care and mental health services
- Renal and related cancers
- 3D Printing in Biomedical Research
- Gastric Cancer Management and Outcomes
- Epigenetics and DNA Methylation
- Metabolomics and Mass Spectrometry Studies
- Helicobacter pylori-related gastroenterology studies
Karolinska Institutet
2016-2025
Karolinska University Hospital
2016-2025
Universitätsmedizin Greifswald
2013-2025
Koblenz University of Applied Sciences
2024
Universität Koblenz
2024
Masaryk Memorial Cancer Institute
2024
Masaryk University
2024
University Hospital Brno
2024
University Hospital Olomouc
2024
National Clinical Research
2024
The optimal intensity of renal-replacement therapy in critically ill patients with acute kidney injury is controversial.We randomly assigned and failure at least one nonrenal organ or sepsis to receive intensive less therapy. primary end point was death from any cause by day 60. In both study groups, hemodynamically stable underwent intermittent hemodialysis, unstable continuous venovenous hemodiafiltration sustained low-efficiency dialysis. Patients receiving the treatment strategy...
Objectives: To achieve the goal of developing international consensus diagnostic criteria (ICDC) for autoimmune pancreatitis (AIP). Methods: An panel experts met during 14th Congress International Association Pancreatology held in Fukuoka, Japan, from July 11 through 13, 2010. The proposed represent a opinion working group. Results: Autoimmune was classified into types 1 and 2. ICDC used 5 cardinal features AIP, namely, imaging pancreatic parenchyma duct, serology, other organ involvement,...
The use of xenogenic or genetically engineered cell types in bioartificial liver support systems requires separation methods between the patients' blood and bioreactors that guarantee sufficient transfer pathophysiologically relevant substances but prevent complications. present paper describes a new membrane system is nearly impermeable to proteins enables exchange water soluble protein bound toxins by special recycled containing dialysate. Because full range hepatic failure has still not...
In hepatorenal syndrome (HRS), renal insufficiency is often progressive, and the prognosis extremely poor under standard medical therapy. The molecular adsorbent recirculating system (MARS) a modified dialysis method using an albumin-containing dialysate that recirculated perfused online through charcoal anion-exchanger columns. MARS enables selective removal of albumin-bound substances. A prospective controlled trial was performed to determine effect treatment on 30-day survival in patients...
Autoimmune pancreatitis (AIP) is a treatable form of chronic that has been increasingly recognised over the last decade. We set out to better understand current burden AIP at several academic institutions diagnosed using International Consensus Diagnostic Criteria, and describe long-term outcomes, including organs involved, treatments, relapse frequency sequelae.23 from 10 different countries participated in this multinational analysis. A total 1064 patients meeting Criteria for type 1...
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cause of cancer related death. It lethal in nearly all patients, due to an almost complete chemoresistance. Most if not drugs that pass preclinical tests successfully, fail miserably patient. This raises question whether traditional 2D cell culture correct tool for drug screening. The objective this study develop a simple, high-throughput 3D model human PDAC lines, and explore mechanisms underlying...
Objective: The objective of this study was to clarify the clinical and pathophysiological characteristics autoimmune pancreatitis (AIP) its subtypes (lymphoplasmacytic sclerosing [LPSP] idiopathic duct-centric [IDCP]) seen around world. Methods: An international multicenter survey AIP conducted in 15 institutes from 8 countries. We compared pathologic profiles (n = 731) LPSP 204) IDCP 64) patients. Results: Patients with were approximately 16 years older than Obstructive jaundice a more...
Confocal laser endomicroscopy (CLE) is rapidly emerging as a valuable tool for gastrointestinal endoscopic imaging. Fluorescent contrast agents are used to optimize imaging with CLE, and intravenous fluorescein the most widely agent. Fluorescein FDA-cleared diagnostic angiography of retina. For these indications, safety profile has been well-documented; however, date, not cleared use CLE.To estimate rate serious total adverse events attributable when CLE.We performed cross sectional survey...
Bei diesem Dokument handelt es sich um die aktualisierte Fassung der 2006 erstmals erstellten S3-Leitlinie zum exokrinen Pankreaskarzinom.
The overall objective of these guidelines is to provide evidence‐based recommendations for the diagnosis and management immunoglobulin G4 (IgG4)‐related digestive disease in adults children. IgG4‐related can be diagnosed only with a comprehensive work‐up that includes histology, organ morphology at imaging, serology, search other involvement, response glucocorticoid treatment. Indications treatment are symptomatic patients obstructive jaundice, abdominal pain, posterior pancreatic...
Objective Desmoplasia and hypovascularity are thought to impede drug delivery in pancreatic ductal adenocarcinoma (PDAC). However, stromal depletion approaches have failed show clinical responses patients. Here, we aimed revisit the role of tumour microenvironment as a physical barrier for gemcitabine delivery. Design Gemcitabine metabolites were analysed LSL-Kras G12D/+ ; LSL-Trp53 R172H/+ Pdx-1-Cre (KPC) murine tumours matched liver metastases, primary cell lines, cancer-associated...