- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Biliary and Gastrointestinal Fistulas
- IgG4-Related and Inflammatory Diseases
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Cancer Genomics and Diagnostics
- Ultrasound Imaging and Elastography
- Global Healthcare and Medical Tourism
- COVID-19 and healthcare impacts
- Appendicitis Diagnosis and Management
- Pneumothorax, Barotrauma, Emphysema
- Patient Satisfaction in Healthcare
- Gastrointestinal Bleeding Diagnosis and Treatment
- Vascular anomalies and interventions
- Medical Imaging and Pathology Studies
- Medical Device Sterilization and Disinfection
- Vascular Procedures and Complications
Freeman Hospital
2016-2025
Newcastle upon Tyne Hospitals NHS Foundation Trust
2016-2023
Newcastle University
1995-2023
Newcastle upon Tyne Hospital
2016-2023
Clinical Research Institute
2019
Royal Victoria Infirmary
2013-2016
Glasgow Royal Infirmary
2013
St Thomas' Hospital
2011
<h3>Objectives</h3> Serous cystic neoplasm (SCN) is a of the pancreas whose natural history poorly known. The purpose study was to attempt describe SCN, including specific mortality. <h3>Design</h3> Retrospective multinational SCN diagnosed between 1990 and 2014. <h3>Results</h3> 2622 patients were included. Seventy-four per cent women, median age at diagnosis 58 years (16–99). Patients presented with non-specific abdominal pain (27%), pancreaticobiliary symptoms (9%), diabetes mellitus...
Background and study aims: Open pancreatic necrosectomy is the standard treatment for infected necrosis but associated with significant morbidity, mortality, prolonged hospital stay. Percutaneous or endoscopic are alternative techniques. We evaluated use of patients that could be accessed through posterior wall stomach. Patients methods: retrospectively analyzed indication, patient status according to acute physiology chronic health evaluation (APACHE) 2 severity score, success as primary...
We aimed to evaluate the diagnostic utility of single-operator peroral cholangioscopy (SOC) for indeterminate biliary lesions and its usefulness in electrohydraulic lithotripsy (EHL) stones not amenable conventional endoscopic therapy.All patients undergoing SpyGlass SOC four UK tertiary centres between 2008 2010 were retrospectively enrolled. Patients followed up until death or last clinic visit May 2011. The operating characteristics detecting malignant stone clearance rate after...
Abstract The European Society of Gastrointestinal Endoscopy and United Gastroenterology present a short list key performance measures for endoscopic ultrasound (EUS) retrograde cholangiopancreatography (ERCP). We recommend that endoscopy services across Europe adopt the following seven one minor EUS ERCP, measurement evaluation in daily practice at center endoscopist level: 1 Adequate antibiotic prophylaxis before ERCP (key measure, least 90 %); 2 Antibiotic EUS-guided puncture cystic...
There is emerging evidence that the pancreas may be a target organ of SARS-CoV-2 infection. This aim this study was to investigate outcome patients with acute pancreatitis (AP) and coexistent
<h3>ABSTRACT</h3> Many non-emergency clinical services were suspended during COVID-19 pandemic peak. It is essential to develop a plan for restarting following the equally important protect patients and staff use resources personal protective equipment (PPE) efficiently. The British Society of Gastroenterology Endoscopy Committee Quality Improvement Programme has produced guidance on how restart can be safely delivered. Key recommendations include following: all should have need endoscopy...
Although evidence suggests frequent gastrointestinal (GI) involvement during coronavirus disease 2019 (COVID-19), endoscopic findings are scarcely reported.
Abstract Background A novel fork-tip fine-needle biopsy (FNB) needle has recently been introduced for endoscopic ultrasound (EUS)-guided sampling. The aim of this study was to compare the performance FNB histology and standard aspiration (FNA) cytology in diagnosis solid pancreatic masses. Methods randomized crossover performed patients referred EUS-guided Three passes were taken with each a order. Only samples reported as diagnostic malignancy considered positive. primary end point...
Abstract Background and study aims Pancreatic fluid collection (PFC) is a common complication of pancreatitis for which endoscopic ultrasound-guided drainage first-line treatment. A new single-device, lumen-apposing, covered self-expanding metal stent (LAMS) has been licensed PFC drainage. We therefore present our multicenter experience with the LAMS in prospective case series to assess success rates. Patients methods All adult patients from 11 tertiary centers who had placement July 2015...
Background and study aims Pancreatic neuroendocrine tumors (PanNETs) outcomes are dependent upon grading by Ki67. This compared endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) to aspiration (FNA) in assessing PanNETs. Patients methods All pancreatic histology for PanNET between January 2009 June 2017 was included if EUS sampling performed prior surgical resection. Ki67 grade from FNA FNB samples using correlation coefficient kappa values. Subgroup analysis purely solid lesions,...
Objective. To evaluate the diagnostic utility of single-operator peroral cholangioscopy (SOC) in patients with sclerosing cholangitis. Methods. All cholangitis who underwent SOC procedures due to suspicious biliary strictures, one Swedish and four UK tertiary centers 2008–2012, were retrospectively enrolled. For each procedure cholangitis, another attempted a single stricture same center calendar year was randomly selected as control. Patients followed up until death or last clinic visit...