- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Diabetes and associated disorders
- Abdominal Surgery and Complications
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Appendicitis Diagnosis and Management
- Pancreatic function and diabetes
- Neuroendocrine Tumor Research Advances
- Drug-Induced Hepatotoxicity and Protection
- Pediatric Pain Management Techniques
- Muscle and Compartmental Disorders
- Pain Management and Opioid Use
- Intestinal Malrotation and Obstruction Disorders
- COVID-19 Clinical Research Studies
- Kidney Stones and Urolithiasis Treatments
- Omental and Epiploic Conditions
- Bariatric Surgery and Outcomes
- Nephrotoxicity and Medicinal Plants
- Childhood Cancer Survivors' Quality of Life
- Chemotherapy-induced organ toxicity mitigation
Navarrabiomed
2025
Universidad Publica de Navarra
2025
Complejo Hospitalario de Navarra
2012-2024
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2024
Navarre Institute of Health Research
2016-2024
Universidad de Navarra
2009-2023
Instituto de Investigación Sanitaria del Principado de Asturias
2022
Centro de Investigación Biomédica en Red
2022
Universitat de Miguel Hernández d'Elx
2022
Hospital Universitario Ramón y Cajal
2022
<h3>Objectives</h3> Serous cystic neoplasm (SCN) is a of the pancreas whose natural history poorly known. The purpose study was to attempt describe SCN, including specific mortality. <h3>Design</h3> Retrospective multinational SCN diagnosed between 1990 and 2014. <h3>Results</h3> 2622 patients were included. Seventy-four per cent women, median age at diagnosis 58 years (16–99). Patients presented with non-specific abdominal pain (27%), pancreaticobiliary symptoms (9%), diabetes mellitus...
Early aggressive hydration is widely recommended for the management of acute pancreatitis, but evidence this practice limited.
The aim of this study was to compare and validate the different classifications severity in acute pancreatitis (AP) investigate which characteristics disease are associated with worse outcomes.AP is a heterogeneous disease, ranging from uneventful cases patients considerable morbidity high mortality rates. Severity based on legitimate determinants important correctly describe course disease.A prospective multicenter cohort involving AP 23 hospitals Spain. Atlanta Classification (AC), Revised...
Cholangiocarcinoma (CCA) and pancreatic adenocarcinoma (PDAC) may lead to the development of extrahepatic obstructive cholestasis. However, biliary stenoses can also be caused by benign conditions, identification their etiology still remains a clinical challenge. We performed metabolomic proteomic analyses bile from patients with (n = 36) malignant CCA or PDAC 57), undergoing endoscopic retrograde cholangiopancreatography aim characterizing composition in biliopancreatic disease identifying...
Objective This study aimed to develop and validate a patient-reported outcome measure (PROM) in acute pancreatitis (AP) as an endpoint centred on the patient. Design A PROM instrument (PAtieNt-rePoRted OutcoMe scale pancreatItis, international proSpEctive cohort study, PAN-PROMISE scale) was designed based opinion of patients, professionals expert panel. The validated multicentre prospective describing severity AP quality life at 15 days after discharge main variables for validation. COSMIN...
Objectives. To evaluate the diagnostic yield of endoscopic ultrasonography (EUS) in patients with idiopathic acute pancreatitis (IAP), find factors predictive a positive EUS finding these and investigate whether etiological findings are maintained during follow-up. Material methods. We performed IAP between July 2004 August 2007. recorded epidemiological data, number severity previous bouts gallbladder status. Results. A total 44 were included study. was normal seven (16%). In remaining 37...
Aim. To determine the serum prealbumin (PA), retinol binding protein (RBP), and levels in adult patients with type 1 diabetes (T1D) to analyze some factors related those levels. Methods. A total of 93 (47 women) were studied. Age, gender, BMI, duration diabetes, chronic complications, HbA1c, lipid profile, creatinine, albumin, PA, RBP, recorded. High low parameter groups compared by Mann–Whitney<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Treatment options are limited for acute pancreatitis (AP). Early aggressive fluid resuscitation (AFR) has been widely considered beneficial due to theoretical improvement in end-organ perfusion, including the pancreas and gut, with pancreatic necrosis bacterial traslocation as consequences of ischemia. There is scarce direct evidence its association improved outcomes. Furthermore, it described that AFR may be associated poor outcomes severe AP. WATERFALL an investigator-initiated...
Previous studies have shown changes in the pancreas of type 1 diabetic (T1-DM) patients, similar to those present patients with chronic pancreatitis. Our aim was analyze prevalence endoscopic ultrasound (EUS) criteria for pancreatitis T1-DM, determine association factors related diabetes and define its clinical significance.Eighty-six T1-DM were prospectively included. All them underwent EUS. Standard used. Patients divided into 3 groups according number EUS they met: group A, 0 2 criteria;...