- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer Genomics and Diagnostics
- Minimally Invasive Surgical Techniques
- IgG4-Related and Inflammatory Diseases
- Renal cell carcinoma treatment
- Lung Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic factors in colorectal cancer
- Biliary and Gastrointestinal Fistulas
- Cardiac Arrhythmias and Treatments
- Liver Disease and Transplantation
- Medical Imaging and Pathology Studies
- Pancreatic function and diabetes
- Genetic and Kidney Cyst Diseases
Harvard University
2015-2024
Massachusetts General Hospital
2014-2024
Mount Auburn Hospital
2018-2024
Boston University
2003-2022
Hochschule Düsseldorf University of Applied Sciences
2016-2022
Sheikh Shakhbout Medical City
2022
Yamamoto Hospital
2022
Directorate-General for Interpretation
2021
Johns Hopkins University
2019
University Health Network
2018
This guideline has been approved by the American Association for Study of Liver Diseases and College Gastroenterology represents position both associations. These recommendations provide a data-supported approach to management patients with varices variceal hemorrhage. They are based on following: (1) formal review analysis recently published world literature topic (Medline search); (2) several consensus conferences among experts; (3) Physicians' Manual Assessing Health Practices Designing...
John H. Stone, Arezou Khosroshahi, Vikram Deshpande, K. C. Chan, J. Godfrey Heathcote, Rob Aalberse, Atsushi Azumi, Donald B. Bloch, William R. Brugge, Mollie N. Carruthers, Wah Cheuk, Lynn Cornell, Carlos Fernandez-Del Castillo, Judith A. Ferry, David Forcione, Gunter Kloppel, Daniel L. Hamilos, Terumi Kamisawa, Satomi Kasashima, Shigeyuki Kawa, Mitsuhiro Kawano, Yasufumi Masaki, Kenji Notohara, Kazuichi Okazaki, Ji Kon Ryu, Takako Saeki, Dushyant Sahani, Yasuharu Sato, Thomas Smyrk, James...
<h3>Hypothesis</h3> Widespread use of computed tomography and ultrasound has led to the identification increasing numbers patients with asymptomatic cystic lesions pancreas. <h3>Design</h3> Retrospective case series pancreatic lesions. <h3>Setting</h3> University-affiliated tertiary care referral center. <h3>Patients</h3> Two hundred twelve seen in our surgical practice during 5 years (April 1997-March 2002). <h3>Main Outcome Measures</h3> Presence or absence symptoms, cyst size location,...
Autoimmune pancreatitis (AIP) is a treatable form of chronic that has been increasingly recognised over the last decade. We set out to better understand current burden AIP at several academic institutions diagnosed using International Consensus Diagnostic Criteria, and describe long-term outcomes, including organs involved, treatments, relapse frequency sequelae.23 from 10 different countries participated in this multinational analysis. A total 1064 patients meeting Criteria for type 1...
<h3>Objectives</h3> Serous cystic neoplasm (SCN) is a of the pancreas whose natural history poorly known. The purpose study was to attempt describe SCN, including specific mortality. <h3>Design</h3> Retrospective multinational SCN diagnosed between 1990 and 2014. <h3>Results</h3> 2622 patients were included. Seventy-four per cent women, median age at diagnosis 58 years (16–99). Patients presented with non-specific abdominal pain (27%), pancreaticobiliary symptoms (9%), diabetes mellitus...
Autoimmune pancreatitis (AIP) is a mass forming inflammatory pancreatobiliary-centric disease. Recent reports of multiorgan lesions with increased numbers IgG4 positive plasma cells suggest that AIP may have systemic component. In this study, we explore the nature AIP, investigate relevance subtyping perform systematic study tissue immunoperoxidase, and ultrastructurally evaluate presence immune complexes. Our group consisted 36 patients 21 whom underwent Whipple procedure. On basis pattern...
Endoscopic ultrasound (EUS) may offer a diagnostic tool through the combination of imaging and guided fine-needle aspiration pancreatic cysts. The purpose this investigation was to determine most accurate test for differentiating mucinous from nonmucinous cysts.The results EUS imaging, cytology, cyst fluid biochemical markers were prospectively collected compared in large single-center study (776 patients) using histology or malignant cytology as final standard 198 patients.The mean...
<h3>Objective</h3> Invasive cancers arising from intraductal papillary mucinous neoplasm (IPMN) are recognised as a morphologically and biologically heterogeneous group of neoplasms. Less is known about the epithelial subtypes precursor IPMN which these lesions arise. The authors investigate clinicopathological characteristics impact on survival both invasive component its background IPMN. <h3>Design patients</h3> study cohort comprised 61 patients with (study group) 570 pancreatic ductal...
The aim of this study was to critically analyze the safety revised guidelines, with focus on cyst size and worrisome features in management BD-IPMN.The Sendai guidelines for branch duct (BD) intraductal papillary mucinous neoplasm (IPMN) espouse observation asymptomatic cysts smaller than 3 cm without nodules (Sendai negative). Revised international consensus published 2012 suggest a still more conservative approach, even lesions or larger. By contrast, 2 recent studies have challenged both...
The Papanicolaou Society of Cytopathology has developed a set guidelines for pancreatobiliary cytology including indications endoscopic ultrasound (EUS)‐guided fine needle aspiration (FNA) biopsy, techniques EUS‐FNA, terminology and nomenclature disease, ancillary testing, postbiopsy treatment management. All documents are based on the expertise authors, review literature, discussions draft document at several national international meetings over an 18‐month period synthesis online comments...
Pancreatic cysts are common and often pose a management dilemma, because some precancerous, whereas others have little risk of developing into invasive cancers. We used supervised machine learning techniques to develop comprehensive test, CompCyst, guide the patients with pancreatic cysts. The test is based on selected clinical features, imaging characteristics, cyst fluid genetic biochemical markers. Using data from 436 cysts, we trained CompCyst classify as those who required surgery,...
Colonoscopy for colorectal cancer screening is endoscopist dependent, and colonoscopy quality improvement programs aim to improve efficacy. This study evaluated the clinical benefit safety of using a computer-aided detection (CADe) device in procedures.This randomized prospectively use CADe at 5 academic community centers by US board-certified gastroenterologists (n = 22). Participants aged ≥40 scheduled or surveillance (≥3 years) were included; exclusion criteria included incomplete...