A5090085204- Health Systems, Economic Evaluations, Quality of Life
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Healthcare cost, quality, practices
- Nutritional Studies and Diet
- Healthcare Policy and Management
- Obesity, Physical Activity, Diet
- Advanced Causal Inference Techniques
- Patient-Provider Communication in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Esophageal Cancer Research and Treatment
- Pharmaceutical Economics and Policy
- Primary Care and Health Outcomes
- Rheumatoid Arthritis Research and Therapies
- Lipoproteins and Cardiovascular Health
- Palliative Care and End-of-Life Issues
- Colorectal Cancer Screening and Detection
- RNA Interference and Gene Delivery
- Bone health and osteoporosis research
- Coronary Interventions and Diagnostics
- HIV, Drug Use, Sexual Risk
- Esophageal and GI Pathology
- Liver Disease and Transplantation
Tufts University
2016-2025
Tufts Medical Center
2016-2025
Institute of Clinical Research
2023-2024
Singapore Institute of Manufacturing Technology
2024
Agency for Science, Technology and Research
2013-2024
Northwell Health
2019-2022
Harvard University
2007-2022
Oregon Health & Science University
2018-2022
Boston University
2016-2022
Pacific Health Research and Education Institute
2018-2022
Abstract This study predicts the burden of incident osteoporosis-related fractures and costs in United States, by sex, age group, race/ethnicity, fracture type, from 2005 to 2025. Total were >2 million, costing nearly $17 billion 2005. Men account for >25% burden. Rapid growth disease is projected among nonwhite populations. Introduction: The aging U.S. population will likely lead greater prevalence osteoporosis. Policy makers require precise projections demographic subgroups...
Potential conflict of interest: Dr. Hwang received grants from Merck and Gilead. Chang advises Arbutus. Lok Gilead Bristol‐Myers Squibb. Jonas consults for Squibb Roche. Brown Bzowej Gilead, Allergan Cirius. Terrault Quibb. Wong is a member the United States Preventive Services Task Force (USPSTF). This article does not necessarily represent views policies USPSTF. The funding development this Practice Guidance was provided by American Association Study Liver Diseases. practice guidance...
In this article, the 2010 European League against Rheumatism (EULAR) recommendations for management of rheumatoid arthritis (RA) with synthetic and biological disease-modifying antirheumatic drugs (sDMARDs bDMARDs, respectively) have been updated. The 2013 update has developed by an international task force, which based its decisions mostly on evidence from three systematic literature reviews (one each sDMARDs, including glucocorticoids, bDMARDs safety aspects DMARD therapy); treatment...
This guideline has been approved by the American Association for Study of Liver Diseases and College Gastroenterology represents position both associations. These recommendations provide a data-supported approach to management patients with varices variceal hemorrhage. They are based on following: (1) formal review analysis recently published world literature topic (Medline search); (2) several consensus conferences among experts; (3) Physicians' Manual Assessing Health Practices Designing...
<h3>Importance</h3> Colorectal cancer is the third leading cause of death for both men and women, with an estimated 52 980 persons in US projected to die colorectal 2021. most frequently diagnosed among aged 65 74 years. It that 10.5% new cases occur younger than 50 Incidence (specifically adenocarcinoma) adults 40 49 years has increased by almost 15% from 2000-2002 2014-2016. In 2016, 26% eligible had never been screened 2018, 31% were not up date screening. <h3>Objective</h3> To update its...
<h3>Importance</h3> Lung cancer is the second most common and leading cause of death in US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, 135 720 died disease. The important risk factor for smoking. Increasing age also a cancer. has generally poor prognosis, overall 5-year survival rate 20.5%. However, early-stage better prognosis more amenable to treatment. <h3>Objective</h3> To update its 2013 recommendation, US Preventive Services Task Force (USPSTF) commissioned...
<h3>Importance</h3> The number of deaths from cervical cancer in the United States has decreased substantially since implementation widespread screening and declined 2.8 to 2.3 per 100 000 women 2000 2015. <h3>Objective</h3> To update US Preventive Services Task Force (USPSTF) 2012 recommendation on for cancer. <h3>Evidence Review</h3> USPSTF reviewed evidence cancer, with a focus clinical trials cohort studies that evaluated high-risk human papillomavirus (hrHPV) testing alone or hrHPV...
Interferon–based regimens for the treatment of chronic hepatitis C have become increasingly effective and are able to eradicate virus in more than one half cases. Early identification patients who will not respond is desirable because might be stopped, thereby avoiding expense inconvenience unnecessary therapy. We examined accuracy different degrees viral inhibition during early weeks (early virologic response [EVR]) with pegylated interferon alfa–2b ribavirin (PEG/R) identifying would The...
Trust and confidence are critical to the success of health care models. There two main methods for achieving this: transparency (people can see how model is built) validation (how well it reproduces reality). This report describes recommendations validation, developed by a task force appointed International Society Pharmacoeconomics Outcomes Research (ISPOR) Medical Decision Making (SMDM). Recommendations were iteratively authors. A nontechnical description should be made available...
Recognizing the importance of timely guidance regarding rapidly evolving field hepatitis C management, American Association for Study Liver Diseases (AASLD) and Infectious Society America (IDSA) developed a web-based process expeditious formulation dissemination evidence-based recommendations. Launched in 2014, virus (HCV) website undergoes periodic updates as necessitated by availability new therapeutic agents and/or research data. A major update was released electronically September 2017,...
OBJECTIVES: This study estimated future morbidity, mortality, and costs resulting from hepatitis C virus (HCV). METHODS: We used a computer cohort simulation of the natural history HCV in US population. RESULTS: From year 2010 through 2019, our model projected 165,900 deaths chronic liver disease, 27,200 hepatocellular carcinoma, $10.7 billion direct medical expenditures for HCV. During this period, may lead to 720,700 years decompensated cirrhosis carcinoma loss 1.83 million life those...
<h3>Importance</h3> By 2020, approximately 12.3 million individuals in the United States older than 50 years are expected to have osteoporosis. Osteoporotic fractures, particularly hip associated with limitations ambulation, chronic pain and disability, loss of independence, decreased quality life, 21% 30% patients who experience a fracture die within 1 year. The prevalence primary osteoporosis (ie, without underlying disease) increases age differs by race/ethnicity. With aging US...
<h3>Importance</h3> More than 35% of men and 40% women in the United States are obese. Obesity is associated with health problems such as increased risk for coronary heart disease, type 2 diabetes, various types cancer, gallstones, disability. also an death, particularly among adults younger 65 years. <h3>Objective</h3> To update US Preventive Services Task Force (USPSTF) 2012 recommendation on screening obesity adults. <h3>Evidence Review</h3> The USPSTF reviewed evidence interventions...