A5103000953- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- IgG4-Related and Inflammatory Diseases
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hormonal and reproductive studies
- Pediatric Hepatobiliary Diseases and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Gastroesophageal reflux and treatments
- Biliary and Gastrointestinal Fistulas
- Intestinal Malrotation and Obstruction Disorders
- Ovarian function and disorders
- Tracheal and airway disorders
- Healthcare Operations and Scheduling Optimization
- Silkworms and Sericulture Research
Edinburgh Royal Infirmary
2010-2024
NHS Lothian
2021-2023
John Wiley & Sons (United States)
2020
Hudson Institute
2020
National Cerebral and Cardiovascular Center
2018
Royal Prince Alfred Hospital
2018
The George Institute for Global Health
2018
George Institute for Global Health
2018
Peking University
2018
Westmead Hospital
2018
Oesophageal adenocarcinoma is the sixth most common cause of cancer death worldwide and Barrett's oesophagus biggest risk factor. We aimed to evaluate efficacy high-dose esomeprazole proton-pump inhibitor (PPI) aspirin for improving outcomes in patients with oesophagus.
Objective We aimed to investigate the clinical utility of follow-up oesophagogastroduodenoscopy (OGD2) in patients with severe oesophagitis (Los Angeles grades C or D) through evaluating yield Barrett’s oesophagus (BO), cancer, dysplasia and strictures. Second, we determine if Clinical Frailty Scale (CFS) may be used identify undergo OGD2s. Design/method Patients NHS Lothian an index OGD (OGD1) diagnosis between 1 January 2014 31 December 2015 were identified. Univariate analysis identified...
Volvulus of the sigmoid colon is a condition that, in Western world, predominately affects elderly. In fit patients colectomy, after period decompression, treatment choice. However, this carries high mortality elderly high-risk patients. Percutaneous endoscopic colostomy (PEC) has been reported as for those who are considered risk surgery. We report successful use PEC an 87-year-old lady, recurrent volvulus, without complication. This procedure also used effectively colonic...
Cases of the quarterIgG4-related disease: a novel, important but easily missed condition ABSTRACT Immunoglobulin G4-related disease (IgG4-RD) is multisystem, fibroinflammatory unrecognised in medical science until last decade.It characterised by progressive scarring and dysfunction affected organs tissues including pancreas, hepatobiliary tree, kidneys, salivary glands, retroperitoneum lungs.The diagnosis made with presence numerous IgG4 positive plasma cells within histologically-distinct...
This is an introduction to the Gut tutorial “Chronic pancreatitis: diagnosis and management of complications” hosted on BMJ Learning—the best available learning website for medical professionals, from Group. Chronic pancreatitis a progressive inflammatory condition that leads irreversible loss pancreatic structure function. Eighty percent cases are due alcohol misuse. Chronic usually presents with abdominal pain, followed at variable interval …
Debate is ongoing regarding the need for universal endoscopic follow-up to ensure gastric ulcer healing. We aimed assess value of oesophago-gastro-duodenoscopies (OGDs) healing and stratify patients according risk malignancy by developing a score.All in National Health Service (NHS) Lothian with an index OGD diagnosis between 1 January 2014 31 December 2018 were identified. Data analysed logistic regression identify factors significantly associated cancer; score was derived externally...
Objective In May 2021 we implemented a locally developed gastric ulcer protocol. Patients with low Edinburgh Gastric Ulcer Scores (EGUS) and benign biopsy results at index oesophagogastroduodenoscopy (OGD1) were recommended to not undergo follow-up OGD (OGD2). We aimed validate the EGUS identify any cancer diagnoses since protocol adoption. Design diagnosed OGD1 in NHS Lothian from 24 June 2023 identified. Data regarding rates gathered compared Electronic patient records reviewed for...
<h3>Introduction</h3> Upper GI cancers (oesophageal and gastric cancers) continue to carry a poor prognosis efforts have been focused on achieving early diagnosis improve outcomes. Post-endoscopy upper cancer rates are currently estimated at 11.3%.<sup>1</sup> This has motivated the BSG release updated quality standards in 2017.<sup>2</sup> study aimed evaluate current endoscopy performance prior implementing these standards. <h3>Methods</h3> registry data was obtained for period covering...
<h3>Introduction</h3> In this study we aimed to investigate the clinical utility of follow-up oesophagogastroduodenoscopy (OGD2) in clinically frail patients (according Clinical Frailty Scale) with severe oesophagitis through evaluating, by Los Angeles (LA) grade, yield Barrett's oesophagus (BO), cancer, dysplasia and strictures. <h3>Methods</h3> Patients NHS Lothian an index OGD (OGD1) diagnosis LA grades C or D between 01/01/14–31/12/15 were identified. Univariate analysis identified...
<h3>Introduction</h3> IgG4 associated cholangitis (IAC) may have similar radiographic appearances to primary sclerosing (PSC) and cholangiocarcinoma (CCA). Making the diagnosis is important as IAC usually responds favourably steroids (in contrast PSC) erroneous treatment for presumed CCA be avoided. We assessed whether specialists familiar with these diseases could reliably distinguish between them based on endoscopic retrograde cholangiograms (ERC). <h3>Methods</h3> ERCs (n=104) of patients...