A5075982168- Liver Disease and Transplantation
- HIV/AIDS Research and Interventions
- Liver Disease Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Organ Transplantation Techniques and Outcomes
- HIV-related health complications and treatments
- HIV, Drug Use, Sexual Risk
- Palliative Care and End-of-Life Issues
- Healthcare Operations and Scheduling Optimization
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Abdominal vascular conditions and treatments
- Sleep and related disorders
- Folate and B Vitamins Research
- Healthcare Policy and Management
- Emergency and Acute Care Studies
- Geriatric Care and Nursing Homes
- Sepsis Diagnosis and Treatment
- Respiratory viral infections research
- Bariatric Surgery and Outcomes
- Restless Legs Syndrome Research
Vanderbilt University Medical Center
2018-2025
University of Maryland, Baltimore
2025
NYU Langone Health
2020-2024
Indiana University School of Medicine
2024
Columbia University
2024
The Ohio State University Wexner Medical Center
2017-2023
Rush University Medical Center
2023
Central Coast Local Health District
2018-2021
Newcastle upon Tyne Hospitals NHS Foundation Trust
2020
Royal Victoria Infirmary
2020
Oesophageal adenocarcinoma is the sixth most common cause of cancer death worldwide and Barrett's oesophagus biggest risk factor. We aimed to evaluate efficacy high-dose esomeprazole proton-pump inhibitor (PPI) aspirin for improving outcomes in patients with oesophagus.
ABSTRACT A goal of HIV therapy is to sustain suppression the plasma viral load below detection limits clinical assays. However, widely followed treatment guidelines diverge in their interpretation and recommended management persistent viremia low magnitude, reflecting limited evidence base for this common finding. Here, we review incidence, risk factors, potential consequences low-level (LLV; defined as a level 50 500 copies/ml) very-low-level (VLLV; <50 copies/ml detected by assays that...
Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within HLA region) and 16q23, where closest protein-coding gene is FOXF1. Subsequently, Esophageal Adenocarcinoma Consortium (BEACON) identified loci for near CRTC1 BARX1, within 100 kb FOXP1. aimed identify further SNPs that increased validate previously reported associations.
We characterized associations between frailty and incident cardiovascular disease (CVD), diabetes mellitus (DM), bone disease, mortality within a cohort of aging persons with human immunodeficiency virus (PWH).Participants underwent evaluations using the Fried assessment (baseline annually). Frailty was defined as having ≥3 criteria. Clinical outcomes mortality, CVD events, DM, events were recorded throughout study period to most recent or clinic visit, date clinical outcome, whichever came...
Purpose To assess the feasibility of four-dimensional (4D) flow MRI as a noninvasive imaging marker for stratifying risk variceal bleeding in patients with liver cirrhosis. Materials and Methods This study recruited participants scheduled both gastroesophageal endoscopy. Risk was assessed at endoscopy by using three-point scale: no varices, low risk, high requiring treatment. Four-dimensional used to create angiograms evaluating visibility varices measure volumes main portal vein (PV),...
Bradycardia unresponded to atropin testing was successfully treated with therapeutic plasma exchange in a patient severe COVID-19 complicated by Guillain-Barré syndrome: A case report,
Objectives To describe the short term ability of Australian intensive care units (ICUs) to increase capacity in response heightened demand caused by COVID-19 pandemic. Design Survey ICU directors or delegated senior clinicians (disseminated 30 August 2021), supplemented and New Zealand Intensive Care Society (ANZICS) registry data. Setting All 194 public private ICUs. Main outcome measures Numbers currently available potentially beds case a surge; levels ICU-relevant equipment staff. Results...
Abstract Background The use of doxycycline post-exposure prophylaxis (DoxyPEP) lowers the incidence gonorrhea, chlamydia, and syphilis in men who have sex with transgender women living HIV or taking pre-exposure (PrEP) for HIV. We aimed to implement a standardized protocol increase number appropriate DoxyPEP prescriptions decrease bacterial sexually transmitted infections (STI) our clinic population. Methods Based on existing evidence, flowchart (Figure 1) were developed implemented November...
Objectives: Sleep in the hospital is often disrupted by modifiable factors. When addressing poor sleep hospital, non-pharmacologic strategies should be utilized initially; however, pharmacologic therapies are prescribed first. The objective of this initiative was to determine if pharmacist-led initiation a promotion order set improved quality inpatient sleep. Methods: This prospective, single-center, before-and-after improvement project. Patients admitted adult internal medicine service with...
BACKGROUND The nationally reported metric for Clostridium difficile infection (CDI) relies solely on laboratory testing, which can result in overreporting due to asymptomatic C. colonization. OBJECTIVE To review the clinical scenarios of cases healthcare facility-onset CDI (HO-CDI) and determine appropriateness testing basis presence symptomatic diarrhea order identify areas improvement. DESIGN Retrospective cohort study. SETTING Northwestern Memorial Hospital, a large, tertiary academic...
Subcutaneous phaeohyphomycosis typically affects immunocompetent individuals following traumatic inoculation. Severe or disseminated infection can occur in CARD9 deficiency after transplantation, but the mechanisms protecting against remain unclear. We evaluated a patient with progressive, refractory Corynespora cassiicola and found that he carried biallelic deleterious mutations CLEC7A encoding CARD9-coupled, β-glucan–binding receptor, Dectin-1. The patient's PBMCs failed to produce TNF-α...
Background We characterized associations between smoking, alcohol, and recreational drug use coronary plaque by HIV serostatus within the Multicenter AIDS Cohort Study (MACS). Methods MACS participants (N = 1005, 621 HIV+ 384 HIV-) underwent non-contrast CT scanning to measure artery calcium; 764 angiograms evaluate type extent. Self-reported of tobacco, smoked/inhaled cocaine, methamphetamine, ecstasy, marijuana, inhaled nitrites, erectile dysfunction drugs was obtained at semi-annual...
Utilization of palliative care services in patients dying end-stage liver disease (ESLD) is understudied. We performed a retrospective review among with ESLD unsuitable for transplantation (LT) at tertiary center. Deceased considered LT from 2007-2012 were identified. Patients excluded if they received transplant, had an incomplete workup, lost to follow up or whose condition improved so was not needed. Of the 1,175 reviewed, 116 met inclusion criteria. Forty (34.4%) inpatient (PC)...
Early readmission in patients with decompensated liver cirrhosis leads to an enormous burden on health care use. A retrospective cohort study using the 2013 and 2014 Nationwide Readmission Database (NRD) was conducted. Patients a diagnoses of at least one feature decompensation were included. The primary outcome develop validated risk model for early readmission. Secondary outcomes 30‐day all‐cause rate most common reasons multivariable logistic regression fit identify predictors...