A5054079145- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Healthcare Systems and Public Health
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Inflammatory Bowel Disease
- Biomarkers in Disease Mechanisms
- Liver Diseases and Immunity
- Gut microbiota and health
- Eosinophilic Esophagitis
- Autoimmune and Inflammatory Disorders
- Hepatitis C virus research
- Microscopic Colitis
- Neurological Disorders and Treatments
- Diabetes and associated disorders
- Human Health and Disease
- COVID-19 Clinical Research Studies
- Liver Disease and Transplantation
- Therapeutic Uses of Natural Elements
- Gallbladder and Bile Duct Disorders
- Digestive system and related health
- Alcohol Consumption and Health Effects
Omsk State Medical University
2016-2025
Ministry of Health of the Russian Federation
2019
Введение. При лечении гастроэзофагеальной рефлюксной болезни пациенту обычно рекомендуют внести изменения в образе жизни и назначают лекарственные средства из семейства ингибиторов протонной помпы, однако резистентная к медикаментозным препаратам гастроэзофагеальная рефлюксная болезнь становится все более распространенной проблемой. Помимо роста резистентности терапии ингибиторами помпы последние годы больше обсуждаются вопросы безопасности длительной препаратами данной группы. В этой связи...
Sarcopenia and non-alcoholic fatty liver disease (NAFLD) are common problems associated with aging. Despite the differences in diagnostic methods, a series of studies have appeared recent years that revealed close relationship between sarcopenia NAFLD. NAFLD number pathogenetic mechanisms, which discussed present article, including role insulin resistance at both muscle levels, hormonal imbalance, systemic inflammation, dysregulation myokines, vitamin D deficiency, malnutrition inactivity,...
A clinical case of an extremely rare morphologically verified combination primary biliary cholangitis and hemochromatosis in a patient is presented. brief description literature reference on these diseases are given from the standpoint modern approach to diagnostics, classification, manifestations treatment. The presented observation considers course disease onset present time, including stage self-induced cessation taking necessary medications seeking medical help, which led rapid...
Введение. Неалкогольная жировая болезнь печени на сегодняшний день является наиболее распространенным хроническим заболеванием во всем мире с глобальной распространенностью 32,4%. В настоящее время ведется активный поиск новых терапевтических возможностей ведения пациентов неалкогольной жировой болезнью печени. Вместе тем идет процесс переосмысления действия известных препаратов, в частности урсодезоксихолевой кислоты, позиций точек терапевтического применения и метаболических эффектов...
The human body, like any other, is an intermediate component of the nitrogen cycle in nature. Consuming from external environment form various compounds, body processes it into ammonia - one final products exchange nitrogen-containing substances [1], which removed urea. most active producers are organs with high amino acids and biogenic amines nerve tissue, liver, intestine, muscles. In a state equilibrium, adult consumes releases about 15 g per day, temporary or permanent disruption balance...
To estimate the diagnostic and informative value of clinical laboratory parameters in development progression liver fibrosis patients with nonalcoholic fatty disease (NAFLD) to enhance efficiency their treatment.An open-label case-control study included 77 NAFLD. Clinical examinations were done. search for additional noninvasive markers, investigators studied serum concentrations insulin, leptin, adiponectin, matrix metalloproteinase-9 (MMP-9) its inhibitors, such as tissue inhibitor...
Justification Given the large number of reports on peculiarities liver lesions during Sars-Cov-2 infection [1], a team experts who participated in 23rd Congress Scientific Society Gastroenterologists Russia and 15 National Therapists November 19, 2020 decided to make additions Russian Consensus “Hyperammonemia Adults” published early [2, 3].
Aim. By using mathematical modeling, to evaluate the impact of upper respiratory tract diseases, retro- and micrognathia, body mass index (BMI) on nocturnal pulse oximetry indicators (oxygen saturation level oxygen desaturation index) in outpatients examined for suspected obstructive sleep apnea syndrome (OSAS). Subjects methods. The study enrolled 260 subjects with a mean age 47.8±12.0 years. All examinees underwent outpatient screening during because OSAS. Multislice spiral computed...
Aim: to assess the effectiveness of mebeverine 200 mg BID in patients with post-cholecystectomy gastrointestinal spasm not requiring surgical treatment. Materials and methods. 218 were included 16 clinical centers 14 cities Russia. All had spasms, treatment received (Duspatalin®) BID. The observational assessment period lasted from moment their inclusion into study up 6 weeks post inlusion. therapy results evaluated using visual analog scales (GPA 11-point numeric rating scale) by patient...
Aim . To present the materials of an Expert Council, which was held on September 23, 2019 in Istanbul (Turkey) under auspices a World Gastroenterology Organisation congress and support Abbott company. General provisions During work role motility disorders stomach duodenum, intestines, gall bladder sphincter Oddi development functional diseases digestive system, such as dyspepsia (FD), irritable bowel syndrome (IBS), biliary dyskinesia (BD) discussed, effectiveness antispasmodics prokinetics...
The high prevalence of metabolic syndrome in population has led to the cholelithiasis is important problem modern health care along with coronary heart disease, arterial hypertension and diabetes. main role formation gallbladder pathology patients belongs insulin resistance, atherogenic dyslipidemia, non‑alcoholic fatty liver disease. Тhe prescription ursodeoxycholic acid pathogenetically justified. This article presents views on mechanisms gallstone disease conditions disorders management...
The article reflects the potential for correcting intestinal microbiota disorders in complex therapy of patients with COVID-19. It has been noted that inclusion dietary fiber diet contributes to protection against disruption integrity barrier and may limit bacterial translocation into systemic circulation. possibility using psyllium (Mucofalk) is reflected, action which realized both through its sorption, cytoprotective anti-inflammatory properties viral lesions gastrointestinal tract,...
A review of articles covering the modern views on hepatobiliary system damage features in patients with clinical manifestations metabolic syndrome. 196 original papers published over last 6 years were found using PubMed, MEDLINE, E-library databases, from which 50 picked out for review. Considering high prevalence syndrome, studied problem seems important. The influence obesity and associated insulin resistance at launching systemic inflammation leading to activation immunological cascade...
Введение. Функциональная изжога относится к широко распространенным заболеваниям желудочно-кишечного тракта. Для этой патологии характерна рефрактерная изжога, т. е. отсутствие ее купирования при оптимальном применении ингибиторов протонной помпы, что требует проведения дифференциальной диагностики с другими заболеваниями верхних отделов пищеварительного Функциональную изжогу связывают частыми обращениями за медицинской помощью, необходимостью повторных обследований и, как следствие,...
Ulcerative colitis (UC) is one of the most serious and poor-studied problems modern gastroenterology. This nosology a diffuse inflammation intestinal mucosa, limited to colon with predominant lesion rectum sigmoid colon. Due progressive nature disease, patients require lifelong drug therapy monitoring. Extra-intestinal manifestations are often found in UC represent complex problem that requires close attention specialists appointment pathogenetically-based treatment, including genetically...
Cholelithiasis is a fairly common disease of the digestive system, affecting from 10 % to 15 adult population. Despite many studies devoted this problem, mechanisms formation gallstone have not been fully elucidated. Recently, aspects influence intestinal microbiota on various pathologies gastrointestinal tract such as non-alcoholic fatty liver disease, inflammatory bowel diseases, irritable syndrome, pancreatic gastroesophageal reflux considered. The presented review article examines...
Введение. Благодаря научно-техническому прогрессу и достижениям общественного здравоохранения продолжительность жизни на планете продолжает увеличиваться, что приводит к смене доминирующих заболеваний от инфекционных хроническим неинфекционным, проявляющимся системным воспалением. С помощью современных методов биотехнологий инженерии удалось синтезировать генно-инженерные биологические препараты, способствующие увеличению продолжительности качества жизни, улучшению прогноза многих нозологий,...
Введение. Распространенность саркопении в мире составляет 10% как у мужчин, так и женщин. В последние годы все больше накапливается сведений о повышенной распространенности пациентов с неалкогольной жировой болезнью печени. Известно, что гиподинамия сопровождается уменьшением мышечной массы влияет на профиль выработки миокинов предотвращение дальнейшей потери накопления внутрипеченочного жира. Секреция миокина иризина индуцируется физической нагрузкой, что, по-видимому, объясняет негативное...
Введение. Висмут является в некотором роде редким элементом, по содержанию аналогичен серебру и ртути, однако его производство обходится дешевле, поскольку большие объемы висмута извлекаются качестве побочного продукта переработки меди олова. соединения считаются умеренно безопасными относительно нетоксичными. Относительно низкая токсичность соединений объясняется главным образом их нерастворимостью почти нейтральных водных растворах, например, биологических жидкостях. Кроме того, было...