- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal motility and disorders
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Dysphagia Assessment and Management
- Eosinophilic Disorders and Syndromes
- Cytomegalovirus and herpesvirus research
- Potassium and Related Disorders
- Pericarditis and Cardiac Tamponade
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gut microbiota and health
- Myofascial pain diagnosis and treatment
- Microbial Metabolites in Food Biotechnology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Sclerosis and Related Diseases
- Acupuncture Treatment Research Studies
- Infant Health and Development
- Pleural and Pulmonary Diseases
- Gastrointestinal disorders and treatments
- Pathogenesis and Treatment of Hiccups
- Microscopic Colitis
- Pelvic floor disorders treatments
- Infective Endocarditis Diagnosis and Management
Sechenov University
2016-2025
Moscow State University
2024
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
Aim . Current recommendations of the Russian Gastroenterological Association are developed to acquaint medical practitioners with modern diagnostics, treatment and trends in rational drug therapy for gastroesophageal reflux disease (GERD). General provisions Incidence rate GERD Federation varies from 11.3 23.6%. is diagnosed history laboratory examination evidence. Esophagogastroduodenoscopy (EGDS) allows detection esophagitis various severity cylindrical epithelial metaplasia esophagus. The...
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
Aim : to present the results of an Expert Consensus on standardization indications for surgical treatment gastroesophageal reflux disease (GERD). Materials and methods . The issues GERD were discussed by 39 experts – leading gastroenterologists surgeons from 7 cities Russia, representing 17 institutions. list questions discussion was formed initiative group sent experts. reviewed recent literature, including existing clinical guidelines consensuses, assessed evidence base suggested...
Aim of publication. To present the latest data on adequate diagnostic methods, treatment approaches and features rational pharmacotherapy gastroesophageal reflux disease (GERD) based principles evidencebased medicine to general practitioners. Summary. The prevalence GERD occupies first place other gastroenterological diseases. heartburn that is a leading symptom at 20-40% population developed countries. in Russia ranges 1846%. Diagnosis early stages primary appealability clinical...
Aim. Current recommendations of the Russian Gastroenterological Association on clinical use high-resolution manometry in diagnosis esophageal disorders are intended to assist decision making, terminology standardisation and interpretation data. Key points. In 2018, a joint meeting Neurogastroenterology Motility Group approved unified classification motor function for diagnosis. Gastrointestinal patient complaints typically concern such as dysphagia, regurgitation, heart-burn, chest pain or...
Aim of review. To analyze the basic esophageal pressure metrics according to Chicago classification v3.0, received at high-resolution manometry and present results clinical application. Summary. Nowadays is most exact hi-tech diagnostic method for motor function disorders. The changes identified during investigation are systematized in v3.0. This relatively new was introduced application Russian Federation first time 2011. Vasilenko clinic internal diseases propedeutics, gastroenterology...
Aim . To present the materials of an Expert Council, which was held on September 23, 2019 in Istanbul (Turkey) under auspices a World Gastroenterology Organisation congress and support Abbott company. General provisions During work role motility disorders stomach duodenum, intestines, gall bladder sphincter Oddi development functional diseases digestive system, such as dyspepsia (FD), irritable bowel syndrome (IBS), biliary dyskinesia (BD) discussed, effectiveness antispasmodics prokinetics...
The article discusses the controversial terminology of biliary refl ux gastritis and factors predisposing to its occurrence. Pathogenesis this disease includes 2 main components: disorders motility stomach duodenum, leading duodeno-gastric ux, direct damaging eff ect hydrophobic bile acids lysolecithin on protective barrier mucosa. Clinical picture is nonspecifi c most often corresponds dyspepsia syndrome. Esophagogastroduodenoscopy with biopsy subsequent histological examination, 24-hour...
Aim. A review of the agreement issued by European Society Neurogastroenterology and Motility consensus meeting on functional dyspepsia in 2020. Key points. Expert votes at generally confirmed main statements Rome Criteria Revision IV definition dyspepsia, its aetiology pathogenesis, diagnosis treatment, as well those Kyoto Consensus covering possible association dyspeptic complaints with H. pylori infection. An absent certain statements, especially drug efficacy evaluation, demonstrates...
Aim. The present articleidentifies possible correlations between new parameters for impedance–pH monitoring, such as mean nocturnal baseline impedance (MNBI); post-reflux swallow-induced peristaltic wave index (PSPW); and the main parameter, acid exposure time (AET), well esophageal motor function. authors set out to assess values of MNBI PSPW additional criteria improving diagnostic efficacy impedance-pH completeness clinical phenotyping gastroesophageal reflux disease (GERD), determining...
The prevalence of gastroesophageal reflux disease is steadily rising. number patients with non-erosive increasing worldwide, including the form refractory to standard therapy. This article presents current data on pathogenesis, diagnosis, and therapeutic approaches for disease. Key words: proton pump inhibitors, disease, symptoms
Aim: to present data on the role of bile acids in progression Barrett's esophagus (BE) and development esophageal dysplasia adenocarcinoma provide a rationale for use ursodeoxycholic acid addition basic therapy patients with gastroesophageal reflux disease (GERD). Key points. The prevalence GERD world is 13.98 %. In absence necessary treatment or non-compliance recommended regimens duration drug use, complications develop such as stricture, bleeding, BE, which, turn, risk factor (EAC)....
Aim: to provide the basic points of Expert Panel Russian Gastroenterological Association with discussion measures improve diagnostics, treatment and management chronic gastritis patients. Key points. In Federation in 2021 more than 30 million patients diagnosed “Gastritis duodenitis” were recorded (K29 accordance International Classification Diseases-10). H. pylori incidence rate population has reduced presently is about 40 %. pattern -associated still dominated though percent after...
Aim. These recommendations are developed for practitioners in order to familiarize them with modern diagnostic methods, management features and pharmacotherapy of patients gastroesophageal reflux disease (GERD). General provisions . GERD is the most common reason visit clinics. There esophageal extraesophageal manifestations GERD. Patients' complaints heartburn regurgitation remain sensitive specific clinical The diagnosis established on basis anamnestic data, instrumental examination...
Aim: to demonstrate an artificial intelligence model that optimises the differential diagnosis of achalasia. Material and methods . The study included 75 patients: 52 % men (mean age 44.5 ± 17.8 years) 48 women 45.6 16.6 years,) with a preliminary Patients were divided into four groups: type I, II, III achalasia group patients whose results did not correspond according HRM performed based on Chicago Classification version 4.0. On basis set data from 750 swallows therefore 6750 manometric...
Aim: to familiarize gastroenterologists, therapists, functional diagnostics and general practitioners (family doctors), radiologists, endoscopists with modern methods of diagnosis treatment achalasia the cardia. Key points. Achalasia is an idiopathic neuromuscular disease manifested by a disorder patency cardia due lack coordination between swallowing, reflex opening lower esophageal sphincter, motor tonic activity smooth muscles esophagus. The etiology remains unclear. However, it believed...
This paper is aimed at investigating the microbiota of esophagus and stomach in patients with gastroesophageal reflux disease (GERD) healthy volunteers. Materials methods . The study included 15 suffering from GERD 6 All subjects underwent sampling esophageal gastric contents. obtained samples was performed by sequencing 16S gene ribosomal RNA (rRNA). Results. most common types bacteria volunteers are found to be Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacterium. By...
Aim of review. To present clinical guidelines the Russian gastroenterological association on management cardiac achalasia and cardiospasm to practical doctors. Summary. Cardiac is primary esophageal motor function disorder manifested by impaired lower sphincter relaxation defects thoracic esophagus peristalsis. Etiology disease remains unknown. Three main hypotheses etiology are discussed: genetic, contagious autoimmune. Clinical symptoms disease: difficulty passage solid liquid food through...
This manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for performance, terminology used, and interpretation of anorectal function testing including manometry (focused on high-resolution manometry), rectal sensory test, balloon expulsion test. Based these measurements, a classification system disorders is proposed. Aim to provide information about methods diagnosis new functional wide range specialists general practitioners, therapists,...
Aim. In this work, we aim to analyze the efficacy of treatment for heartburn and pathological gastroesophageal refluxes (GERs) using alginate-antacid medication. We assess dynamics inflammatory process in patients with reflux disease (GERD) treated medication used at conventional dosage, both as a monotherapy part GERD combination therapy. To end, set out confirm formation layer unbuffered acidic gastric juice over chyme after eating, well determine acidneutralizing effect upon its...