A5084695694- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Pathogenesis and Treatment of Hiccups
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- Infant Health and Development
- Eosinophilic Esophagitis
- Digestive system and related health
- Microscopic Colitis
- Congenital gastrointestinal and neural anomalies
- Whipple's Disease and Interleukins
- Respiratory Support and Mechanisms
- Dysphagia Assessment and Management
- Regulation of Appetite and Obesity
- Myofascial pain diagnosis and treatment
- Complementary and Alternative Medicine Studies
- Child Nutrition and Feeding Issues
- Pneumothorax, Barotrauma, Emphysema
- Clostridium difficile and Clostridium perfringens research
- Acupuncture Treatment Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Medical and Biological Ozone Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
KU Leuven
2019-2025
Universitair Ziekenhuis Leuven
2021
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
Abstract Background Gastroparesis is a condition characterized by epigastric symptoms and delayed gastric emptying (GE) rate in the absence of any mechanical obstruction. The challenging clinical practice lack guidance concerning diagnosis management gastroparesis. Methods A Delphi consensus was undertaken 40 experts from 19 European countries who conducted literature summary voting process on 89 statements. Quality evidence evaluated using grading recommendations assessment, development,...
Abstract Background/Objectives The global epidemiology of gastroparesis is unknown. European UEG and Society for Neurogastroenterology motility consensus defines Gastroparesis as a condition characterized by delayed gastric emptying in the absence mechanical obstruction, with symptom pattern nausea and/or vomiting overlapping postprandial distress syndrome (PDS). Real‐world evidence this gastroparesis‐like crucial step understanding gastroparesis. Methods In Rome Foundation Global...
Gastroparesis is a condition characterized by epigastric symptoms and delayed gastric emptying (GE) rate in the absence of any mechanical obstruction. The challenging clinical practice lack guidance concerning diagnosis management gastroparesis.A Delphi consensus was undertaken 40 experts from 19 European countries who conducted literature summary voting process on 89 statements. Quality evidence evaluated using grading recommendations assessment, development, evaluation criteria. Consensus...
Abstract Background Prokinetics are a class of pharmacological drugs designed to improve gastrointestinal (GI) motility, either regionally or across the whole gut. Each drug has its merits and drawbacks, based on current evidence as high‐quality studies limited, we have no clear recommendation one other. However, there remains large unmet need for both selective and/or globally acting prokinetic that work primarily intraluminally safe without systemic side effects. Purpose Here, describe...
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
Summary Background The European consensus defined gastroparesis as a condition characterised by delayed gastric emptying (GE) in the absence of mechanical obstruction, with symptom pattern predominant nausea and/or vomiting and overlapping postprandial distress syndrome (PDS). distinction between patients those functional dyspepsia (FD), another gastrointestinal PDS or epigastric pain symptoms, is ongoing. Aim To investigate extent that patterns may differentiate from FD. Methods This...
Introduction: In functional dyspepsia, increased gut permeability, low-grade inflammation and altered sensorimotor function have been reported. Both stress corticotropin-release hormone(CRH) shown to increase small bowel permeability in a mast-cell dependent fashion. Moreover, eosinophil-derived CRH has implicated activation. The aim of this study was evaluate whether administration alters duodenal immune activation healthy volunteers(HVs). Methods: An intravenous bolus 100μg or placebo...
In healthy volunteers, peripheral corticotropin-releasing hormone (CRH) infusion accelerates gastric-emptying rate and increases postprandial gastric response, accompanied by a rise in symptoms, but does not alter sensitivity or meal-induced accommodation. These findings underscore significant link between stress dyspeptic with CRH playing pivotal role mediating these effects.
Abstract Background Dyspepsia is a prevalent condition in the general population. Besides organic causes, differential diagnosis of dyspepsia includes functional (FD) and gastroparesis (GP) which share similar pathophysiological mechanisms clinical presentation. So far, no study investigated prevalence FD GP primary care Belgium. Methods Data were obtained from Intego, Flemish‐Belgian practice‐based morbidity registration network. From 586,164 patients between 2000 2021, we selected with...