A5003008153- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal motility and disorders
- Colorectal Cancer Screening and Detection
- Diet and metabolism studies
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Liver Disease and Transplantation
- Hepatitis C virus research
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Pharmacology and Obesity Treatment
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Diverse Scientific Research Studies
- Apelin-related biomedical research
- Biochemical Analysis and Sensing Techniques
- Cardiovascular and exercise physiology
- Cytokine Signaling Pathways and Interactions
- Liver Diseases and Immunity
- Nutrition, Genetics, and Disease
- Neuropeptides and Animal Physiology
- Galectins and Cancer Biology
- Diet, Metabolism, and Disease
- Phonocardiography and Auscultation Techniques
Medical University of Silesia
2015-2025
Centrum Medyczne iMed24
2020-2024
University Clinical Centre
2023
University of Silesia in Katowice
2009-2021
Jan Długosz University
2017
Silesian Center for Heart Disease
2017
Górnośląskie Centrum Medyczne
2015
Institute of Occupational Medicine and Environmental Health
2015
Creative Research Enterprises (United States)
2015
University Gastroenterology
2009
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
Objective. Chemerin and vaspin are new adipokines which may modulate inflammatory response insulin sensitivity in non-alcoholic fatty liver disease (NAFLD). The aims of this study were to assess: (1) circulating levels chemerin their association with histology markers injury NAFLD patients; (2) the relationship between analyzed resistance. Material methods. A total 41 patients body mass index (BMI) 30.4 ± 3.3 kg/m2 [20 steatohepatitis (NASH) BMI 30.3 21 simple steatosis/uncertain NASH...
AIM:To investigate serum adipokine levels in inflammatory bowel disease (IBD) patients before treatment and after achieving clinical remission. METHODS:Serum concentrations of six adipokines (tissue growth factor-β1, adiponectin, leptin, chemerin, resistin, visfatin) were studied 40 subjects with active IBD [24 Crohn's (CD) 16 ulcerative colitis (UC)] three months therapy corticosteroids and/or azathioprine.Clinical diagnoses based on ileocolonoscopy, computed tomography or magnetic...
Summary. Adipocytokine profile seems to play a distinct role in the pathogenesis of chronic hepatitis C (CHC). Chemerin and vaspin are recently described adipocytokines with various suggested functions potential modulate inflammatory response insulin resistance (IR). We assessed chemerin, leptin serum concentration studied their association IR laboratory morphological features patients C. The study included 40 20 healthy volunteers, similar age body mass index (43.6 ± 11.6 vs 40.9 11.8 years...
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite its prevalence, FD associated with major uncertainties terms definition, underlying pathophysiology, diagnosis, treatment, and prognosis.A Delphi consensus was initiated 41 experts from 22 European countries who conducted a literature summary voting process on 87 statements. Quality evidence evaluated using grading recommendations, assessment, development, evaluation (GRADE) criteria. Consensus...
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range gastrointestinal non‐gastrointestinal conditions. Diagnosis can be challenging requires systematic well‐structured approach. If the initial investigation for structural, toxic metabolic disorders is negative, digestive motility gut‐brain interaction should assessed. United European Gastroenterology (UEG) Society Neurogastroenterology Motility (ESNM) identified need an updated, evidence‐based clinical guideline...
Omentin and vaspin are adipokines potentially considered in the development of liver pathology. Irisin is new myokin participating energy processes organisms. The aim this study was to evaluate plasma concentration these cytokines relationships them with selected parameters laboratory tests histopathological changes chronic diseases: non-alcoholic fatty diseases (NAFLD), primary biliary cholangitis (PBC) alcoholic cirrhosis (AC). omentin highest AC group lowest control (CG). CG AC. Mean...
Summary. Visfatin is a new adipokine involved in several processes. The data concerning visfatin chronic hepatitis C (CHC) small. To assess serum concentration and to study its association with biochemical morphological features CHC. Seventy nonobese patients CHC (Group 1) confirmed by the presence of virus (HCV)-RNA 20 healthy volunteers 2), similar age BMI normal fasting glucose lipid profile were included. was significantly increased Group 1 compared 2 (55.6 ± 23.1 vs 23.7 3.8 ng/mL; P <...
Natural origin substances with healing properties of potential use in the treatment different diseases, particularly wound management, remain scientific and research interest for many years.The substance natural potentially wide medicine pharmacy is snail mucus.The study aims to evaluate effect mucus extract on human fibroblasts biological cytotoxic activity this substance.In present study, NHDF fibroblast cells were exposed slime at two concentrations: 15 µL/mL 70 µL/mL.Moreover, assessment...
Introduction . Chemerin seems to be involved in pathogenesis of chronic hepatitis C (CHC). Hepatic expressions chemerin and its receptor, chemokine receptor-like 1 (CMKLR1), CHC have not been studied so far. Aim To evaluate CMKLR1 hepatic expression together with serum concentration patients assess their relationship metabolic histopathological abnormalities. Methods The study included 63 nonobese patients. Transcription was assessed by quantitative real-time PCR, while enzyme-linked...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kajor M, Kukla Waluga et al. Hepatic chemerin mRNA in morbidly obese patients with nonalcoholic fatty liver disease. Polish Journal of Pathology. 2017;68(2):117-127. doi:10.5114/pjp.2017.69687. APA Kajor, M., Kukla, Waluga, Liszka, Ł., Dyaczyński, & Kowalski, G. (2017). Pathology, 68(2), 117-127. https://doi.org/10.5114/pjp.2017.69687 Chicago Maciej, Michał Marek Łukasz Grzegorz and Dominika Żądło 2017....
Abstract Background The aim of the study was to assess sex‐ and gender‐related differences in epidemiology impact disorders gut–brain interaction (DGBI) Poland. Methods Data used for current analysis were derived from Polish population sample 2057 subjects (1030 F, 1027 M) collected via Internet survey that included Rome IV diagnostic questionnaire 80 supplementary questions. Key Results overall prevalence DGBI Poland 46.0% (51.7% women 40.3% men, p < 0.001). Comparing versus esophageal...
Vaspin was found to modulate insulin resistance (IR) and inhibit proinflammatory profibrogenic agents. The aim of the study evaluate vaspin serum concentration prior after antiviral treatment assess its relationship with morphological alterations, IR response therapy. encompassed 75 non-obese, non-diabetic chronic hepatitis C (CHC) patients, 30 whom underwent treatment. Serum levels decreased in CHC patients positively associated fibrosis stage (r = 0.44, p 0.001). significantly higher...
Chronic hepatitis C (CHC) is accompanied by numerous metabolic disorders, partially associated with altered adipokine system regulation. Omentin (intelectin-1) a novel known to play pivotal role in regulation CHC. In group of 63 CHC patients (29 men/34 women) infected genotype 1b, aged 6.6 ± 14.6 years, serum omentin levels and its gene expression liver tissue were examined their association histopathological features was assessed. Serum significantly higher compared controls (p < 0.001),...
Aim: To analyze the relationship between pretreatment clinical or histological features and levels of soluble platelet-endothelial cell adhesion molecule-1 (sPECAM-1) vascular (sVCAM-1), to determine their serum concentration in responders nonresponders, evaluate behavior under antiviral therapy, explain response therapy assess association these two molecules chronic hepatitis C (CHC). Methods: The study analyzed 65 CHC patients, including 50 patients (Group 1) with marked fibrosis treated...
Low caloric diet is a commonly accepted treatment in obesity. However, owing to moderate results, pharmacological support has been proposed. As some efficacious drugs activate overall sympathetic activity, they might modify functions of the cardiovascular system. Three groups subjects were studied: (1) nine obese women receiving only standard hypocaloric diet; (2) and ephedrine (2 × 25 mg) with caffeine 200 mg); (3) yohimbine 5 mg). The state was evaluated by thoracic electrical...